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Biomedical subjects

A Perrenoud

Publications and source records attributed to A Perrenoud.

10 recordsLinked to original sources
PubMed1996

Discography with manometry and discographic CT: their value in patient selection for percutaneous lumbar nucleotomy.

In minimally invasive spinal surgery and percutaneous disc surgery the exact preoperative structural analysis of the disc herniation becomes a prerequisite in patient selection. Discography including discal manometry and discographic CT (in addition to CT and MRI) are used to review the anatomy of disc herniations prior to surgery. The analysis of the findings of discography in 360 lumbar discs examined from 1988 to 1994 are presented. In 68 discs operated with hemilaminectomy, later intraoperative findings were available for comparison with preoperative discographic findings. The diagnostic accuracy of determining the exact anatomical location of the herniation with discography alone was 75%. The diagnostic accuracy increased to 99.55% with the use of CT discography. The authors conclude that CT discography is an accurate and useful diagnostic aid.

Diskectomy, Percutaneous↗
PubMed1996

Locked posterior dislocation of the shoulder.

The posterior dislocation of the shoulder is a rare but clinically and radiologically well-defined entity. Missing its diagnosis can lead to locked dislocations, incorrect treatment, and shoulder dysfunction. The cases in this series will illustrate the typical errors of diagnosis and treatment, and the possible and recommended management strategies.

Adult↗
PubMed1993

[Emerging diseases and demography dynamics].

The point of view presented in this work is not that of the epidemiologist interested in the etiology of diseases and their specific effect on mortality rates; but rather the view of the demographer who attempts to establish the influence that diseases have on evolution and population dynamics. It is not until the 19th century that the 'unification microbienne' of the world is reached and one has clinical and statistical data on the major diseases. Consequently, it is not possible to have an exact demographic picture of infectious diseases in their emerging phase. To understand globally this effect one may create a conceptual framework capable of integrating all the aspects of mortality rates: genetic, socio-biological and human. The scheme proposed here allows for a description and at the same time an evaluation of a given historical situation, how a population achieves protection from lethal diseases and what are the factors determining receptivity or resistance to a disease. This approach serves to study the interdependent relations that link all elements involved in a given morbid process.

Communicable Disease Control↗
PubMed1993

[Possibilities of shoulder arthroscopy in comparison with magnetic resonance tomography and arthro-computerized tomography].

In the last 15 years the methods of examination of the shoulder have intensively expounded. According to a well documented retrospective study we describe the value of the shoulder arthroscopy and its correlation to MRI and arthro-CT findings. MRI represents nowadays the best way of exploring rotator cuff lesions and of investigating an impingement syndrome. Associated with a contrast medium its ability to clear up an anterior or posterior shoulder instability is now superior to the arthro-CT's. The arthroscopy allows the dynamic exploration of the joint and can be used not only as a diagnostic but also as a therapeutic procedure.

Adolescent↗
PubMed1992

[Chronic posterior shoulder dislocation].

The posterior dislocation of the shoulder is frequently unrecognized for many days, months or even years after the initial accident. After the presentation of its clinical and radiological features, as the different ways of its treatment, some cases will illustrate this entity, too frequently missed or wrongly treated.

Adult↗
PubMed1991

[Physical therapy aspects of treatment following total hip prosthesis].

Our physiotherapy program after total hip arthroplasty is presented, and certain modifications in relation to cemented or cementless implantations are discussed. Three different stages must be considered: preoperative instructions of the patient, mobilization of the patient and his joints, water gymnastics to enable the patient to obtain total independence. During the first three months only partial weight should be put on the operated leg. In comparison to the cemented system, the biomechanical properties of the cementless prosthesis permit only a careful and delayed mobilization and charge of the operated leg, as long as a secondary stability of the implant has not been reached. In more complicated cases it is of importance that the whole planning of postoperative physiotherapy should be discussed individually and in detail with the surgeon concerned.

Bone Cements↗
PubMed1991

[Cause of death in the 17th and 18th centuries in Geneva: nosology and disease spectrum. Perspectives and objectives of a study].

For the twenty years of 1740-1759, the authors analyze, for the city of Geneva, the causes of death as officially indicated on the bills of mortality. This study is part of a larger analysis of mortality: over a longer period, the whole gamut of disease--pathocoenosis--will be studied, and some light should be shed by this on the causes of the decline of mortality in the 18th century. The data are analyzed with regard to age, sex and season and interpreted according to ancient as well as modern medical criteria.

Cause of Death↗
PubMed1990

Efficacy of intranasal human calcitonin in patients with Paget's disease refractory to salmon calcitonin.

PURPOSE: A cause for the resistance to intranasal salmon calcitonin (sCT) therapy in patients with Paget's disease is the occurrence of neutralizing antibodies to sCT. As a result, a new formulation of intranasal human calcitonin (hCT) was developed, and the efficacy investigated in patients treated earlier with sCT. PATIENTS AND METHODS: Twelve patients with Paget's disease were treated twice daily for 6 months with 1 mg synthetic hCT administered intranasally. Five patients demonstrated low-titer antibodies to sCT, and four of the patients did not respond previously to 1-year therapy with intranasal sCT. The hypocalcemic effect of 3 mg hCT was compared to that of 0.1 mg sCT before and after the intranasal hCT therapy. Serum alkaline phosphatase and the ratio between the urinary excretion of hydroxyproline and creatinine were measured before and during intranasal hCT treatment. RESULTS: The hypocalcemic response to 3 mg intranasal hCT (-6.60 +/- 0.67%, mean +/- standard error) was similar before and at the end of intranasal hCT therapy (-5.92 +/- 0.80%, p greater than 0.1). Intranasal sCT (0.1 mg) lowered serum calcium less effectively (-2.86 +/- 0.76%) than 3 mg intranasal hCT (p less than 0.05). The presence of low-titer antibodies to sCT did not affect the hypocalcemic response to sCT or hCT. As a result of the 6-month intranasal hCT regimen, serum alkaline phosphatase and urinary hydroxyproline/creatinine ratio were reduced to 62 +/- 5% (p less than 0.001) and 80 +/- 7% (p less than 0.05) respectively, of pretreatment levels. In four patients previously resistant to intranasal sCT therapy because of neutralizing antibodies to sCT, serum alkaline phosphatase was similarly lowered by intranasal hCT to 66 +/- 6% of pretreatment levels (p less than 0.05). CONCLUSION: A new formulation of intranasal hCT effectively lowered serum calcium levels, alkaline phosphatase concentrations, and urinary hydroxyproline excretion in patients with Paget's disease, some of whom were previously resistant to intranasal sCT because of neutralizing antibodies.

Administration, Intranasal↗