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Biomedical subjects

A Paxton

Publications and source records attributed to A Paxton.

At least 37 records · Page 2Linked to original sources

Maternal body fat and water during pregnancy: do they raise infant birth weight?

OBJECTIVE: Our purpose was to determine the relation to infant birth weight of maternal fat and lean tissue during early and late pregnancy. DESIGN: Total and net maternal pregnancy weight, fat, and water were determined from measurements of total body water, body density, and bone mineral mass in 200 women, with the use of a multicompartment model for body fat estimation in early and late pregnancy. Regression modeling was used to determine the relation of maternal body composition to birth weight, with control for maternal age, height, parity, and race and for infant gestational age and sex. RESULTS: Maternal weight and body water at term were significantly associated with infant birth weight, but maternal body fat at term was not. These relations remained when maternal net values were used for weight, fat, and water to eliminate the contribution of the conceptus to these components. CONCLUSION: In well-nourished women delivering at term, maternal body fat near term does not contribute significantly to infant birth weight, but maternal body water does.

Adipose Tissue↗

Maternal reporting of prepregnancy weight and birth outcome: consistency and completeness compared with the clinical record.

OBJECTIVES: We examined whether data obtained by maternal report could be used for research in clinical settings in place of abstraction of the clinical record. METHOD: Reported prepregnancy weight, delivery type, and infant's birth date, birth weight, and length were compared to the same information from the clinical record. RESULTS: Reported data, obtained from 198 women, were more complete than data in the 168 clinical records obtained. Prepregnancy weight from the clinical record was highly correlated with weight measured by us in early pregnancy, and with the value reported by the mother (differing significantly only in underweight women, who overreported by 2.4 lbs). There was complete concordance on birth date and method of delivery, and no significant differences in mean birth weight or length, between the reported and recorded information. CONCLUSION: The mother's report is a satisfactory substitute for clinical record data, being consistent with the record, and more complete, yet easier to obtain for clinical studies.

Birth Weight↗

Anthropometric equations for studying body fat in pregnant women.

Anthropometric data from 200 pregnant women were used to estimate body fat at gestation weeks 14 and 37 and changes in body fat from week 14 to week 37 with four formulas from the literature. The resulting estimates were evaluated against the estimation of fat by a four-compartment model that determined fat from weight, total body water, bone mineral mass, and body density. The estimates of fat by existing anthropometric models were statistically different from those by the four-compartment model in both early and late pregnancy. Most importantly, the change in body fat estimated by the anthropometric models (all > 4 kg) was considerably higher than that estimated by the four-compartment model (3.3 kg). Two new anthropometric equations were developed, both of which used the four-compartment model as the reference method. The equation for predicting change in fat mass from week 14 to 37 of pregnancy was as follows: 0.77 (change in weight, kg)+ 0.07 (change in thigh skinfold thickness, mm)-6.13 (r2 = 0.73). The equation for determining fat (kg) at term was as follows: 0.40 (weight at week 37, kg)+ 0.16 (biceps skinfold thickness at week 37, mm) + 0.15 (thigh skinfold thickness at week 37, mm)-0.09 (wrist circumference at week 37. mm)+ 0.10 (prepregnancy weight.kg)-6.56 (r2 = 0.89). Both equations were derived on a randomly selected half of the total sample and validated on the remaining half. Both equations were found to be valid for use in studying pregnant women with different prepregnancy body mass indexes, different gestational weight gains, different ethnicities, and different socioeconomic status.

Adipose Tissue↗