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Biomedical subjects

A Patrizi

Publications and source records attributed to A Patrizi.

At least 127 records · Page 7Linked to original sources
PubMed1983

Virological course of herpes zoster in otherwise normal hosts.

The virological course of herpes zoster infection in 42 otherwise normal hosts was studied by virus isolation and antibody titration. Varicella-zoster virus (VZV) was isolated from vesicle fluid from all three patients examined on the first day of the vesicular eruption and from five out of six examined on the second day. The isolation rate fell to one out of six patients on the seventh day of illness and VZV was not isolated from patients at a later stage of the illness. IgG antibodies were detected by IFAMA and ELISA, in sera from all the patients by the end of the first week of illness; IgG antibody titres were highest during the second and the third weeks. IgM antibodies to VZV were detected in sera from six of the 42 patients with herpes zoster after fractionation by ion-exchange chromatography.

Adult↗
PubMed1983

Unusual acquired hyperkeratosis: a case report.

The authors describe an acquired hyperkeratosis occurring in a 74-year-old male. To the authors' knowledge this disease shows a pathological picture never before described in the literature, consisting of the presence of a large number of acrosyringum-like structures not connected with the dermal sweat ducts in hyperkeratotic skin.

Acanthosis Nigricans↗
PubMed1983

Acute gangrene of the scrotum and penis in a patient with acute promyelocytic leukemia. A case of acute necrotizing gangrene.

The authors describe a case of Fournier's gangrene in a young man affected with acute promyelocytic leukemia. They emphasize the rarity of this disease especially in a patient affected with leukemia. Pseudomonas aeruginosa with the same strict antibiotic sensitivity has been found in cutaneous lesions and in several blood cultures. The Fournier's gangrene etiology is discussed.

Acute Disease↗
PubMedDate not supplied

Nevus comedonicus syndrome: a new pediatric case.

Nevus comedonicus (NC) is an uncommon developmental defect of the pilosebaceous apparatus. The individual lesions are large comedones often arranged in groups or in a linear pattern. Nevus comedonicus syndrome (NCS) is a well-defined disorder within the large group of epidermal nevus syndromes. In patients suffering from NCS, the nevus is associated with noncutaneous abnormalities including skeletal defects, cerebral anomalies, and cataracts. We report a 9-year-old boy with open comedones in a linear pattern localized to the right cheek, clinodactyly and polydactyly of the first right finger, bilateral syndactyly of the second and third toes, and some depigmented hairs since birth.

Biopsy↗
PubMedDate not supplied

Psoriasiform acral dermatitis: a peculiar clinical presentation of psoriasis in children.

Recently an unusual chronic dermatosis, considered a new clinical entity and closely resembling psoriasis, has been described in the literature under the term psoriasiform acral dermatitis (PAD). It is characterized by cutaneous involvement of the digits without nail dystrophy. We describe three young patients, ages 6 to 8 years, in whom this condition was associated with psoriasis. Two children were affected by psoriasis vulgaris, while the third had a palmoplantar psoriasis. All laboratory investigations performed were within normal limits. Skin biopsy specimens taken from the fingers of two patients revealed the pathologic features of subacute spongiotic dermatitis. Histologic examination of a biopsy specimen taken from an erythematous squamous patch confirmed the clinical diagnosis of psoriasis in two patients. The dermatitis showed a fluctuating course in all three patients, with only a moderate to strong improvement with therapy with calcipotriol ointment (50 microg/g). During follow-up, two patients experienced marked spontaneous, persistent improvement, while the disease slightly worsened in the third. The children had features similar to those described in PAD, but were also suffering from psoriasis. Whether PAD is a distinctive entity or just a clinical manifestation of psoriasis in children is still an open question. We strongly believe this latter hypothesis, although further studies are needed to confirm it.

Acrodermatitis↗
PubMedDate not supplied

A pediatric case of dermatofibrosarcoma protuberans: an immunohistochemical study.

Dermatofibrosarcoma protuberans (DFSP) is a fibrohistiocytic tumor of intermediate malignancy that usually occurs in early or mid-adult life as a nodular cutaneous mass. DFSP has rarely been reported during childhood or at birth. We report a case of childhood DFSP that illustrates the usefulness of immunohistochemical analysis in the differential diagnosis between DFSP and other fibrohistiocytic proliferations occurring in the skin. A prompt and correct diagnosis is very important in order to ensure appropriate treatment and to prevent local recurrences.

Child↗
PubMedDate not supplied

The natural history of sensitizations to food and aeroallergens in atopic dermatitis: a 4-year follow-Up.

The natural history of atopic dermatitis (AD) is variable. Generally the dermatitis disappears during the first years of life, but it is often followed by the appearance of allergic respiratory diseases (ARDs). Our aim was to establish the risk factors for developing an ARD in children with AD. We followed up for 4 years 78 children (51 boys, 27 girls) with mild (26%), moderate (48%), and severe (26%) AD (clinical score proposed by Rajka and Langeland). In all the patients IgE serum levels were checked and skin prick tests (SPTs) were performed at the first examination. The SPTs were repeated in 68 children at the end of the study. The children with severe AD had significantly higher IgE serum levels than those with mild or moderate AD. SPTs at the first observation were positive in 47% of cases, mostly in patients with severe AD, with a prevalence of food allergens, particularly in younger patients. At the second observation, SPTs were positive in 65% of cases, including 100% of children with severe AD. Inhalants were the most common allergens. An ARD appeared in 38% of all patients: in 75% of those with severe AD and in 54% of those with a positive first SPT. Allergic screening should be carried out at an early age, especially in severe AD, since SPT positivity to food allergens, associated with severe clinical AD symptoms and a high IgE serum level, identifies those children ages 0-3 years at high risk of development of ARD.

Air Pollutants↗
PubMedDate not supplied

Childhood allergic contact dermatitis from henna tattoo.

Henna is a shrub cultivated in India, Sri Lanka, and North Africa; it is used, mixed with other substances, as a hair and body dye. Several cases are reported in the literature of sensitization to para-phenylenediamine (PPD) contained in the henna tincture, but few of these are pediatric cases. We report two instances of allergic contact dermatitis due to temporary tattoos in children. In one case a patch test was positive for PPD. We suggest that the fashion of temporary henna tattoos in children is to be discouraged due to the serious consequences that a sensitization to PPD could have in their future.

Child↗
PubMedDate not supplied

Porokeratosis in the elderly: a new subtype of disseminated superficial actinic porokeratosis.

In a review of all cases of porokeratosis histologically diagnosed in our Department during the period 1991-98 we found that 12 patients (22%) were in their seventh to ninth decade. In all 12 (2 males and 10 females) the age of onset of the disease varied between 58 and 89 years (mean age 68.6 years). The clinical picture was similar in all the patients, with the number of lesions varying from a few to 20-50 annular plaques 10-15 mm in diameter, localized mainly on the lower limbs. We suggest that our patients had a very mild form of disseminated superficial actinic porokeratosis confined to the extremities with an unusually late onset. This peculiar variety of late-onset disseminated superficial actinic porokeratosis may represent a type of immunosuppression-induced porokeratosis where the pathologic clone for porokeratosis is present but remains latent until the amount of sun exposure, together with the physiological age-related lowering of immunocompetence, bring about its proliferation.

Age of Onset↗