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Biomedical subjects

A Parisi

Publications and source records attributed to A Parisi.

At least 91 records · Page 5Linked to original sources

[24-hour pH measurement and Holter ECG monitoring in studying patients with angina-like chest pain. Our experience].

Preliminary experience with the combined use of 24 pH-metering and Holter ECG monitoring in the differential diagnosis of angina-like-pain (ALP) is reported. Twenty patients aged 24-65 (15 females and 5 males) all with angina-like-pain were studied. The aim of the study was to differentiate between oesophageal and cardiac causes of the various types of chest pain and to investigate the possibility of their coexistence. 50% of the ALP patients with a negative non-invasive cardiological report presented a pathological gastroesophageal reflux. In 5% of the cases simultaneous coronary insufficiency and pathological gastro-oesophageal reflux was noted. The importance of performing both Holter recordings and pH-metering before subjecting patients to coronarography is therefore emphasised.

Adult↗

Dynamic and ultrastructural studies of in vitro interaction between Toxoplasma gondii and cultured cell lines. I. Adhesion and cellular penetration.

Toxoplasma gondii is a protozoan parasite that requires an intracellular environment for growth and replication. This study describes the early phase of the interaction between the parasite and its host cell. With the aid of phase contrast microcinematography, it has been possible to observe adhesion to cell membrane, and the closely following intracellular penetration. This report also reviews the ultrastructural and biochemical grounds that could account for the infecting process.

Animals↗

[A case of primary intestinal lymphoma].

The authors examine primary small bowel tumours, dealing at some length with problems of a diagnostic and clinical nature. The difficulties often encountered in reaching an early diagnosis and the feasibility of radical surgery frequently prove to be factors conditioning prognosis. The importance is then stressed of thorough evaluation of those vague symptoms which may be the only manifestation of this disease.

Aged↗

[Endoscopic excision of a pin implanted in the 3d portion of the duodenum].

The Authors, while presenting a case of endoscopic extraction of a foreign body fixed in the duodenum, underline the value of operative endoscopy, which, going beyond the limits of a exclusively diagnostic technique, is intended as a first choice therapeutic procedure to be always carried out, leaving to surgery the treatment of the most complicated cases and those where the endoscopic attempt fails.

Adult↗

[A case of vascular leiomyosarcoma of the superficial soft tissues].

The authors report a case of vascular leiomyosarcoma of the superficial soft tissues, and point out its epidemiologic (rareness of the report), biologic (high degree of malignancy, trend to local relapse and remote conversion into metastases), histopathologic aspects. They consider significant as to prognostic value the appraisal of the "mitotic index" and the opportunity of a radical intervention, followed by radiotherapy. They, moreover, think it useful, in consideration of the frequency of the relapses, to perform a periodic checking of the patient.

Aged↗

Somatostatin in the treatment of severe gastrointestinal bleeding from peptic origin. A multicentric controlled trial.

Results of a multicentric controlled trial on the efficacy of somatostatin in the treatment of severe gastrointestinal bleeding from peptic origin is reported. The trial was carried out on 90 patients presenting with severe bleeding from hemorrhagic gastric disease in 20 cases, from gastric ulcer in 31 and from duodenal ulcer in 39. Diagnosis was ascertained by endoscopy. Fifty-three patients were treated with somatostatin; in 95% of cases the bleeding was controlled in an average time of 7h 37'. Thirty-seven patients were treated with H2 receptors antagonists and the bleeding was controlled in 76.3% of cases in an average time of 21h. Cases treated with somatostatin required a lower amount of blood transfusion (1 Unit/patient, against 2.7 Units). The better efficacy of somatostatin, at least on a temporary basis, in the control of severe upper gastrointestinal bleeding is underlined while keeping in mind that prevention of recurrence is still an open question.

Acute Disease↗

[Protocols for the diagnostic verification of lymph node toxoplasmosis].

The protocol we have fixed for the diagnosis of lymphonodal toxoplasmosis includes a precise succession of tests: 1) specific repeated serological tests (I.H.A.T., I.F.A.T., IgM--I.F.A.T. on total serum and on pure IgM fraction); 2) lymphonodal biopsy for histological examination and biological test (isolation procedure in mouse). We have evaluated the effectiveness of our protocol in 20 cases that we observed during 1980.

Adolescent↗

[Current clinical aspects of leptospirosis].

Leptospirosis is still endemic in the Po valley. It has an extremely protean clinical picture. In a series of 79 cases diagnosed at Pavia in the period 1970-79 hepatonephritic forms were the most common (29.1%), followed by febrile or pseudo-influenza forms (25.3%), hepatitis (20.2%), nephritis (17.8%), and meningitis (7.6%). Febrile hepatonephritis was always accompanied by the most severe pictures. Timely antibiotic management with penicillin or ampicillin, and above all the early use of peritoneal dialysis (carried in 10 subjects) enable a final cure to be obtained even in these cases. The only death in that series did not appear to be ascribable to the disease itself.

Adolescent↗

[Importation of malaria to Lombardy. II - Analysis of hospitalized cases].

Among 210 cases of imported malaria, officially notified in Lombardy from 1976 to 1980, we have selected 142 hospitalized patients and, about these, we got detailed informations on the stay in malaria endemic areas, on chemoprophylaxis and on their principal clinical data. We have found statistically significant correlations between P. falciparum infection and all the most frequent values in every class of epidemiological parameters considered, particularly with provenience from tropical African countries, touristic motivation, stay less than 30 days in winter season, onset of the illness within 20 days after the return in Italy, diagnostic lag shorter than 10 days after the onset and fever remission 2 or more days after starting specific treatment. There is also a tight correlation between these clinical parameters and the absence of individual chemoprophylaxis. The definition of these factors of risk is particularly useful to plan out some programs of prevention that should managed by regional Centers.

Chloroquine↗

[Importation of malaria to Lombardy. I - Analysis of reported cases].

The comparative analysis of the cases of imported malaria in Lombardy and in Italy during 1976-1980, shows that the prevalent factors of risk are, in both, the male sex, the young age, the stay in endemic areas of tropical Africa where P. falciparum is greatly prevalent. The only very significant difference is represented by the prevalence of touristic motivation of the stay among the cases of Lombardy. The efficacy of prophylaxis against these factors of risk allowed to note, in the two last years considered (1979-1980), a sharp reduction of the annual number of cases in opposition to the trend of European cases of malaria.

Female↗

[Post-transfusion malaria after imported malaria].

A case of falciparum malaria transmitted by a whole blood transfusion from a donor affected by imported malaria is reported. As an increased number of cases of transfusion malaria is reported in Europe during the past ten years, the authors emphasize the importance of screening blood donors by the I.F.A. test to identify carriers. They also discuss some related diagnostic and therapeutic problems.

Adult↗

A new complement fixation test for toxoplasmosis. Comparison with other serological methods.

A new complement fixation test for toxoplasmosis has been compared with the classical test indirect immunofluorescence test (IFAT) and indirect haemoagglutination test (IHAT). Neither false positive or negative results were obtained with LBCF-H100-TTE. Notably these values correlate well with IFA titers. Furthermore LBCF-H100-TTE shows the highest titers in acute cases and its time course is practically superimposable to IFAT. The differences obtained performing these different tests on the preferential detection of different antigen antibodies systems by these 3 tests are discussed.

Complement Fixation Tests↗

Diagnostic protocols for lymphoglandular toxoplasmosis.

The diagnostic protocol for lymph node toxoplasmosis presented in this study is based on the following sequence: 1. specific serologic tests (IHAT, IFAT, IgM-IFAT) on total serum and on purified IgM serum fraction, performed twice, within a time interval of 21-28 days; 2. Lymph node biopsy for histologic studies and for isolation of the parasite in mice (biologic test). A critical analysis is reported for 20 cases submitted to this protocol in the course of the year 1980.

Adolescent↗

Increased radiation resistance of vegetative Bacillus pumilus.

A 4.5-fold increase in vegetative cell radiation resistance of Bacillus pumilus E601, the internationally recognized biological standard for irradiation sterilization, was obtained by the repeated passage of resistant survivors through successive sublethal doses of (60)Co irradiation. This increase in resistance was accompanied by a corresponding increase in spore resistance through the seventh irradiation passage. By the fifteenth passage, the ability for spore formation was lost. Other effects noted by the successive irradiation dosages included loss of motility and pellicle formation, and changes in the Gram reaction, cell morphology, and colonial morphology. Increased resistance was also accompanied by an increased nutritional requirement for specific amino acids. Radiation resistance was not transferred from vegetative cells to spores.

Amino Acids↗