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Biomedical subjects

A Paoletti

Publications and source records attributed to A Paoletti.

At least 37 records · Page 2Linked to original sources
PubMed1984

Biological monitoring of workers in the rubber industry. II. UV-induced unscheduled DNA synthesis in the lymphocytes of vulcanizers.

DNA-repair ability was estimated in a group of vulcanizers by measuring in vitro UV-induced unscheduled. DNA synthesis (UDS) in peripheral lymphocytes, and compared with that of an adequate control group. A considerable interindividual variability was shown by the UDS responses of the subjects studied both in the control and exposed population. Significantly (P = 0.0158) decreased UDS values were observed among the vulcanizers as compared to the referents. Neither age nor cigarette-smoking was observed to affect the UDS response, thus suggesting an association between the industrial exposure and decrease in the DNA-repair rate.

Cells, Cultured↗
PubMed1984

Mutagenicity studies in a tyre plant: in-vitro activity of urine concentrates and rubber chemicals.

A possible occupational contribution to urinary mutagenicity was studied in a tyre plant, by assaying concentrates of urine from 72 workmen and 23 controls for their activity in the Ames test and microtitre fluctuation test. The results show that smoking habits but not occupation are related to the appearance of a detectable urinary mutagenicity in strain TA98. A possible synergistic effect of occupation was, however, observed among tyre builders who were smokers. Mutagenicity screening of 25 rubber chemicals, of major technological relevance and used in high volume in the workplace investigated, showed that three of them are weakly active in TA98 and TA100 (tetramethylthiuram disulfide) or TA98 alone (poly-p-dinitrosobenzene and mixed diaryl-p-phenylendiamines).

Chemical Industry↗
PubMed1982

[An unusual case of "acute abdomen". Dimethylformamide poisoning].

Dimethylformamide, an industrial solvent largely used, causes intoxication both by inhalation and cutaneous adsorption. The Authors report the case of a young worker suffering from abdominal pain and hepatopathy who was heavily exposed to the solvent. A first diagnosis made by the surgery department was that of acute cholecystitis without gallstones. In the three successive years the worker was controlled and did not show relevant consequences of intoxication.

Abdomen, Acute↗