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Biomedical subjects

A Pannike

Publications and source records attributed to A Pannike.

At least 73 records · Page 4Linked to original sources
PubMed1980

[Microangiographic and histologic findings in the tibiae of rats after implantation of bone cement (author's transl)].

The reaction of bone tissue to the filling of the medullary cavity with acrylic bone cement was studied in the rat by histological and microangiographic methods. Three months after plugging, the fibrous borderline tissue between cement and bone had changed into newly formed bone with a secondary medullary cavity, depending on the content of monomer next to the tissue. The blood support of the bone came from periosteal vessels. After 6 months a definitive secondary medullary cavity had been established, the cement was enveloped by newly formed primary bone, and the inner and middle portions of the cortical bone had been invaded by vessels originating from the secondary medullary cavity.

Angiography↗
PubMed1978

[Concentration of lysozyme during mineralization in callous tissue of healing fractures (author's transl)].

Investigations have suggested that lysozyme (E.C. 3.2.1.17) is involved in bone mineralization. High concentrations of lysozyme is found in the growth plate near cartilage bone junction, where it is located at the collagen fibrils and in the ground substance. Quantitative studies of lysozyme levels were made in ossifying tissue of healing fractures, to confirm the existence of this relationship on bone repair. Callous tissue, serum samples and normal bone was collected from 42 rats at 15 intervalls during a 50 day healing period. Agar gel diffusion test was used for quantitation of lysozyme. Electrophoresis of tissue extract and standard henn egg white lysozyme served as control. Lysozyme levels in callous tissue increased significantly (4--5-fold) from 4.--21. day p. trauma and subsequently decreased. The concentration in serum samples did not change significantly. Changes in Ca concentration and histological studies during tests confirm a direct relationship between bone mineralization and lysozyme level changes.

Animals↗