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Biomedical subjects

A Pannella

Publications and source records attributed to A Pannella.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Gastric carcinoma in the aged].

After examining the literature on the subject, all patients aged over 60 and admitted to the Surgical Pathology Department of Pavia University from 1-1-1974 to 31-12-1985, suffering from gastric carcinoma have been considered. From the results obtained it is concluded that stomach cancer is a disease that preferentially affects the IIIrd age, usually occurring with atypical symptomatology that leads the patient to underestimate the seriousness of the disease, and impeding early diagnosis that would be effective for therapeutic purposes. It is therefore essential for the necessary examination to be carried out at the first warning symptoms. Further, the general state of these patients has to be controlled and appropriate treatment sought to treat the various accompanying conditions and so prepare the patient for operation.

Aged↗
PubMed1989

[Non-neoplastic pathology of the pancreas in the elderly].

After examining the literature on the subject, all patients of the IIIrd age suffering from non-neoplastic pathology of the pancreas are considered. The results show that this pathology contains more acute pancreatitis and fewer chronic pancreatitis (at times a consequence of the acute) cases. Pancreatic cyst was also noted. The age most affected by this pathology is the 6th decade and the average age encountered in the series was 60, as is also stated by Camatte and Sarles. It is concluded that the above-mentioned conditions that affect the 6th decade and specially the 60th year of life may be held to involve the IIIrd age.

Acute Disease↗
PubMed1989

[Pathology of the bile ducts in the elderly].

After examining the literature on the subject, all admissions to the Pavia University Department of Surgical Pathology from 1-1-1974 to 31-12-1985 belonging to the IIIrd age and suffering from non-neoplastic and neoplastic bile way pathology have been reviewed. The two groups were studied on the basis of their histories and laboratory examinations, the outcome of the operation and its complications. It was found that in patients affected by non-neoplastic pathology (lithiasis of the bile ways, alithiasic cholecystitis, etc.) the operation of choice was well tolerated, unlike emergency surgery which in most cases was dangerous. In the IInd group, on the other hand, general condition is very important because on this depends whether or not resective or derivative intervention is carried out. It should be noted here that in all IIIrd age patients associated diseases have to be studied closely for these can contribute to death. It is concluded that in the Ist group of patients, operation can take place in optimal general and local conditions so that the operation can be of choice and not emergency. In the IInd group, as soon as the general condition of the patient so permits, the operation must be as extensive as possible, as age is not an impediment to surgery.

Age Factors↗
PubMed1989

[Peptic ulcer in the elderly].

The Authors, after having reviewed all the literature on this topic, have studied all patients over 60 which were admitted with a diagnosis of peptic ulcer disease at the Institute of Surgical Pathology of the University of Pavia from January 1, 1974 until December 31, 1985. They noted, from their results, that this disease shows a predilection for adults, but is also frequently found in the elderly. In fact, in the latter, during this period of life, the complications which are most frequently observed (especially gastric) are hemorrhage and perforation; according to the Authors the former is due to arteriosclerosis which hinders vascular contraction, while the latter to a reduction of blood flow due to endarteritis, which causes necrosis of the ulcer's base, creating therefore a "locus minoris resistentiae". The Authors conclude that in the elderly, when drug therapy is inefficient, a surgical approach is necessary. In fact, with a well followed pre-operative care program the outcome of surgery is usually satisfactory and complications (mentioned above), which would render surgery and the post-operative period difficult, are prevented.

Age Factors↗
PubMed1975

[A case of intestinal duplication. Clinical study].

Reference to the relevant literature is followed by the presentation of a personal case of ileal duplication, in which pain led to an a mission diagnosis of appendicitis, whereas surgery revealed a second ileum, rising about 6-7 cm from the caecum and running for 35 cm into the sigmoid colon. The aetiopathogenesis of this abnormality is discussed. Pain, as in the present case, is evaluated with respects to its interpretation in preoperative diagnosis.

Appendicitis↗
PubMedDate not supplied

[Effect of male and female hormones on the appearance and development of experimental 20-methylcholanthrene-induced tumors in young albino rats].

A review of the relevant literature is followed by an investigation of the effect of male and female hormones on the onset and growth of 20-methylcholanthrene induced tumours in approximately 15-day-old rats. The results indicated that oestrogens facilitate the onset of tumours in females, and hinder it in males, whereas testosterone provokes tumours in both males and females, contrary to what happens in the adult rat. It is felt that the latter finding can be ascribed to the fact that, since the transformation of oestradiol from testosterone usually takes place at 12 months (Di Prisco et al)., the antagonist effect between hormones of different sex which appears to oppose tumour growth had not yet occurred. This, then could be one of the reasons for carcinogenesis in female rats treated with testosterone, aided by hormonal stimulus of cell glycolysis.

Age Factors↗
PubMedDate not supplied

[Portacaval anastomosis with a bypass of lyophilized dura mater. Experimental research in young dogs].

A review of the relevant literature is followed by an account of the use of freeze-dried dura mater prostheses in the construction of porta-cava anastomoses in young dogs. Results of an experiment showed that involution of the dura mater in the new passage between the porta and the cava was followed by the establishment of connective tissue only, and later by the appearance of smooth muscle. The conclusion is drawn that this material gives satisfactory results and is ripe for further development, using various modalities.

Animals↗
PubMedDate not supplied

[The quality of life of the elderly after a surgical intervention. II. Gastric carcinoma].

Having reviewed the literature on this topic, the authors examined the "quality of life" of elderly patients undergoing surgery for gastric carcinoma over the past 5 years. From the results obtained it was seen that the most frequent operation was total gastrectomy (51.1%), followed by gastric resection (48.9%); it was therefore possible to assert that living patients were all well, with a score of 100 on Karnofsky's scale (22.40%), despite the high percentage of deaths during the period examined. The authors therefore concluded that, given that the "quality of life" of those undergoing surgery was satisfactory, it is worthwhile operating whenever possible to give geriatric patients the possibility of leading a normal life.

Age Distribution↗