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Biomedical subjects

A P Weiss

Publications and source records attributed to A P Weiss.

At least 19 recordsLinked to original sources
PubMed2000

Late-onset obsessive-compulsive disorder: a case series.

Obsessive-compulsive disorder (OCD) is a common and potentially disabling illness with onset usually in the second or third decade of life. Onset after age 50 is relatively rare and may be more likely to have an organic etiology. Out of an OCD patient population of over 1,000, the authors found 5 cases in which symptoms of OCD first developed late in life. Four of the 5 patients had intracerebral lesions in the frontal lobes and caudate nuclei, findings consistent with current theories about the pathogenesis of "idiopathic" OCD.

Age of Onset↗
PubMed2000

Thoracic outlet syndrome.

Thoracic outlet syndrome (TOS) is an often misdiagnosed cause of neck, shoulder, and arm disability. Neurovascular compression may be seen in the interscalene triangle, costoclavicular space, or posterior to the pectoralis minor, although any cause of abnormalities of shoulder girdle alignment may cause a localized area of brachial plexus compression. Nerve compression in this way may lead to upper extremity weakness, pain, paresthesias, and numbness. A careful and detailed medical history and physical examination are essential to proper identification of thoracic outlet syndrome, which remains primarily a clinical diagnosis. Diagnostic testing may differentiate other causes of pain or neurologic symptoms of the upper extremity from TOS. Clinical management is often challenging.

Angiography↗
PubMed1999

Neuroimaging of hallucinations: a review of the literature.

While hallucinations have been described for over two millennia, their cause remains unclear. Brain-based models suggest that abnormal cerebral excitation and a lack of normal cerebral inhibition may play primary roles, but evaluation of these hypotheses has been hampered by difficulty in studying the hallucinatory state. Recent advances in neuroimaging have provided researchers with tools to study a variety of mental states, including hallucinations. We review the literature regarding the structural and functional neural correlates of hallucinations. Despite small sample sizes and methodological differences, several studies describe similar results: hallucinations are associated with sensory modality-specific activation in cerebral areas involved in normal sensory processing. Furthermore, neural activation may be specifically related to distinct phenomenological features of the hallucinatory experience. Further work is needed to better understand the neural basis of hallucinations.

Adult↗
PubMed1999

Mania associated with St. John's wort.

BACKGROUND: St. John's wort, the popular herbal remedy touted as an antidepressant, is generally thought to be benign, with few reported side effects. Given its possible efficacy as an antidepressant, evaluation of its propensity to cause affective switching should be evaluated. METHODS: This report presents two cases of mania temporally associated with the use of St. John's wort (hypericum). RESULTS: As with other antidepressant agents, St. John's wort may precipitate hypomania, mania, or an increased cycling of mood states, particularly in patients with occult bipolar disorder. CONCLUSIONS: Because the majority of people who take this popular over-the-counter preparation do so without formal psychiatric evaluations, risk of hypericum-induced mania may be significant. Physicians should screen patients for a history of hypomania or mania before recommending use of St. John's wort for depression.

Adult↗
PubMed1999

Traumatic nerve injuries about the elbow.

Although not common, nerve injuries about the elbow occur because of the proximity of the three upper extremity nerves or because of the relationship of the median, ulnar, and radial nerves to the bony and soft-tissue structures about the elbow joint. Nerve injuries at and about the elbow joint occur more frequently with fractures than with any other kind of trauma. Nerve injuries may be found with periarticular fractures, dislocations, gunshot wounds, lacerations, and other iatrogenic causes.

Brachial Plexus↗
PubMed1999

Portable mini-fluoroscopy improves operative efficiency in hand surgery.

A paired case cohort study was performed using retrospective review of operative times for defined hand surgical procedures in an attempt to quantify efficiency with and without the use of portable fluoroscopy. Patients included in the study underwent 1 of 4 defined surgical procedures controlled to ensure similar operative technique (total wrist fusion, in situ 4-corner fusion, closed reduction/internal fixation using K-wires of phalangeal shaft fractures, and metacarpophalangeal or interphalangeal joint fusions using K-wires). One group used intraoperative standard film radiographs and the other used portable mini-fluoroscopy to examine hardware placement. Both groups were paired by operative procedure to eliminate procedure bias on overall operating time. Analysis demonstrated a 38% reduction in total operative time in the group using portable mini-fluoroscopy compared with standard intraoperative radiographs.

Arthrodesis↗
PubMed1999

Diagnostic imaging and arthroscopy for wrist pain.

Chronic wrist pain may be evaluated by physical examination, imaging, and arthroscopy. Arthroscopy provides an attractive diagnostic and therapeutic modality in selected patients. Currently the correlation between arthroscopic findings and symptomatic pathology is not clear, because arthroscopy often identifies asymptomatic pathology. Nevertheless, the ability to diagnose and treat intra-articular pathology simultaneously provides a substantial advantage over radiographic analysis.

Arthralgia↗
PubMed1998

Scapholunate ligament reconstruction using a bone-retinaculum-bone autograft.

This study was designed to evaluate the use of a locally available bone-retinaculum-bone graft in the reconstruction of the completely torn scapholunate (SL) ligament. Nineteen consecutive patients (14 with dynamic instability and 5 with static instability) underwent SL ligament reconstruction using an autogenous bone-retinaculum-bone graft taken from the third dorsal compartment region. All patients underwent arthroscopy to document a torn SL ligament. The bone plugs on the graft were fitted into the dorsal scaphoid and lunate, respectively, with the retinaculum periosteal soft tissue intervening sleeve arching between these 2 bones. The SL interval was reduced and pinned for 8 weeks with cast immobilization. The follow-up period averaged 3.6 years (minimum, 24 months). Of the 14 patients with dynamic instability, 12 had no pain and 2 had pain with heavy activity of the wrist. Range of motion (ROM) decreased slightly from preoperative values, and grip strength improved 46%. Thirteen patients were completely satisfied and returned to their former work activities, and 1 returned to modified work activities. Of the 5 patients with static instability, 2 had no pain after surgery, 1 had pain with heavy activity, and 2 had constant pain. ROM in this group decreased moderately in extension/flexion from the preoperative values. Grip strength improved 30% from preoperative values. Satisfaction was rated as complete by 1 patient and partial by 2 patients; 2 patients were dissatisfied. Two patients returned to their former jobs, 2 returned to modified duties, and 1 is on disability. Reconstruction of the SL ligament using a bone-retinaculum-bone autograft is predictable in patients with dynamic instability. Use of this technique with static SL instability is questionable; these patients may require a stronger construct to prevent recurrence of the SL gap.

Adult↗
PubMed1998

Scapholunate ligament reconstruction using a bone-retinaculum-bone autograft: a biomechanic and histologic study.

A new surgical technique has been recently described that involves reconstruction of the dorsal aspect of the scapholunate ligament (DSLL) with a bone-retinaculum-bone (BRB) autograft preparation from Lister's tubercle. In this study, the mechanic and histologic properties of the 2 tissues were compared. The BRB and DSLL specimens were harvested from 6 fresh-frozen human cadaveric forearms. The specimens were measured and then tested in tension with an MTS 810 servohydraulic materials testing machine at a rate of 10 mm/min. The BRB autograft was significantly weaker than the DSLL. However, because the mean cross-sectional area of the DSLL was more than 3 times as large as that of the BRB autograft, the failure stress (failure force/cross-sectional area) of the BRB autograft was not significantly different from that of the DSLL. Histologically, the DSLL and BRB autograft were also similar. These findings suggest that the BRB autograft may be appropriate graft material for scapholunate ligament reconstruction, but that structural parity with DSLL will ultimately depend on remodeling and hypertrophy during healing. This also highlights the importance of using a large BRB autograft to approximate the strength of the DSLL as much as possible, and that the BRB autograft must be protected postoperatively as it heals and remodels.

Aged↗
PubMed1998

The results of revision carpal tunnel release following previous open versus endoscopic surgery.

This study compared the outcomes of revision open carpal tunnel release following previous open versus endoscopic release to determine whether revision surgery has different results based on the type of initial surgical treatment. Thirty revision carpal tunnel releases were performed in 13 wrists that had previous endoscopic release and in 17 wrists with prior open release. At a follow-up visit an average of 30 months after surgery, self-assessment questionnaires demonstrated improved or complete symptom relief in 77% of the postendoscopic release group versus 47% in the previous open release group. Combining both groups, 18% of workers' compensation patients improved after revision surgery compared with 84% of those with conventional insurance (p < .05). Patients having persistent or recurrent symptoms following a previous endoscopic carpal tunnel release have a greater chance of symptom improvement or resolution compared with patients who had previous open carpal tunnel surgery. Our results support the observation that a higher incidence of incomplete release of the carpal tunnel is found with endoscopic surgery than with open release.

Adult↗
PubMed1998

Acute and chronic effects of nicotine on anastomotic patency following ischemia/reperfusion.

The effect of nicotine on anastomotic patency was studied using an isogenic rat-knee transplantation model. Animals were divided into experimental and control groups, with experimental animals exposed to either 40 days of twice-daily nicotine injections (Group 1-chronic exposure) or acute nicotine exposure by graft perfusion (Group 2-acute exposure). Four and 6 hr warm ischemia times were studied. Syngeneic rat knees were transplanted from donor to recipient by microvascular anastomosis of the femoral vessels. There was a statistically significant difference (p < 0.05) in anastomotic patency after 4 hr of ischemia in Group 1 animals exposed to nicotine (33 percent patency) vs. controls (89 percent patency). In addition, there was a statistically significant difference in anastomotic patency after 4 hr of ischemia in Group 2 animals exposed to nicotine (11 percent patency) vs. controls (67 percent patency). No significant differences between controls and Group 1 animals were noted in anastomotic patency after 6 hr of ischemia. Both acute and chronic nicotine exposure reduces anastomotic patency after short intervals of warm ischemia in vascularized composite tissue grafts. This detrimental effect is lost when the ischemic interval is prolonged to periods with poor anastomotic patency rates related to the ischemia/reperfusion itself.

Anastomosis, Surgical↗
PubMed1998

Congenital anomalies of the hand.

This manuscript reviews the basic and most common types of congenital hand anomalies seen by the pediatrician. Each disorder is categorized into the standard classification system used, and the main highlights of each condition are detailed with representative illustrations. Other system anomalies associated with congenital hand problems are also identified.

Female↗
PubMed1997

The cervical spine in Marfan syndrome.

STUDY DESIGN: Prospective radiographic and clinical analysis of a consecutive unselected population of persons with Marfan Syndrome. OBJECTIVES: To determine cervical spine abnormalities present in the Marfan population compared with that seen in the general population. SUMMARY OF BACKGROUND DATA: In the treatment of a large population of patients with Marfan Syndrome, three serious cervical spine disorders were noted. To the authors' knowledge, no report of cervical abnormalities in patients with Marfan Syndrome exists in the literature. Therefore, the cervical spine in these patients was studied in a systematic fashion. METHODS: An unselected group of 104 consecutive patients with Marfan Syndrome seen at a medical genetics follow-up examination underwent lateral neutral and flexion-extension cervical spine radiographs. Parameters of alignment, size, and stability were measured. Patients with Marfan Syndrome aged 35-45 years and matched controls were given a pain questionnaire to complete. RESULTS: The prevalence of focal kyphosis was 16%. A large number of patients with Marfan Syndrome (54%) had increased atlantoaxial translation. The preadolescent Marfan population has a greater range of motion than either the adolescent or adult populations. The Marfan population has an increased radiographic prevalence of basilar impression (36%), and the odontoid height (3.69 +/- 0.53 cm) was larger than reported norms (2.34 +/- 0.22 cm). Cervical stenosis was rare, with 3% having a critical Torg ratio at C3 and 2% having a critical Torg ratio at C6. Neck pain frequency did not differ significantly from that of age-matched controls. CONCLUSION: Based on the increased prevalence of several cervical bony and ligamentous abnormalities, patients with Marfan Syndrome were recommended to avoid sports with risks of high-impact loading of the cervical spine. Given the rarity of actual neurologic injuries in the Marfan population, however, radiographs for all patients with Marfan Syndrome undergoing general anesthesia is not recommended.

Adolescent↗
PubMed1997

Grip and pinch strength variations in different types of workers.

We measured grip and pinch strengths in non-manual, light manual and heavy manual workers using a Jamar dynamometer and a pinch measuring device. Heavy manual workers had the strongest grips with the least difference between sides. Office workers had the weakest grips and the greatest difference between sides. Light manual workers were between these two groups. Consequently, the occupation of the patient must be taken into account when using grip and pinch strength measurements to assess the need for rehabilitation and in medicolegal reports.

Adult↗
PubMed1997

Primary care of hand and wrist athletic injuries.

Athletic injures to the hand and wrist can range from simple sprains to severe fractures or soft-tissue disruptions that can permanently threaten the normal function of the extremity. This article deals with some of the more commonly noted sports-related injures to the hand and wrist to help the team physician make the correct diagnosis and establish the most effective treatment plan, so that the athlete may achieve maximum results and ultimately return to full participation in their sport.

Adolescent↗
PubMed1997

Malignant eccrine poroma of the hand: a case report.

Carcinoma of sweat glands is a very rare neoplasm that is difficult to diagnose clinically and histologically. This report presents a case of malignant eccrine poroma of the hand which is a distinct histologic subtype of sweat gland carcinoma with a high local recurrence rate. A distal radial artery based forearm flap was used to provide soft tissue coverage.

Acrospiroma↗
PubMed1997

Ulna-shortening osteotomy after failed arthroscopic debridement of the triangular fibrocartilage complex.

Over a 4-year period, 160 wrist arthroscopies were performed at 1 institution. Ninety-seven patients had central or nondetached ulnar peripheral tears of the triangular fibrocartilage complex (TFCC). All these patients underwent debridement with an arthroscopic shaver. Thirteen of the 97 had persistent pain in the TFCC region for more than 3 months after surgery. At an average of 8 months after failed arthroscopic debridement of the TFCC, all 13 patients underwent a 2-mm-long ulna-shortening osteotomy with fixation by a 3.5-mm 6-hole dynamic compression plate. At follow-up examination (an average of 2.3 years later), 12 of the 13 had complete relief of pain at the ulnar side of the wrist. One patient continued to complain of pain with moderate to heavy activity use of her hand. Four of the 13 had postoperative complications: 1 had traumatic pull-out of the screws requiring reinsertion and distal radius bone graft, 1 had nonunion at 4 months after surgery that required iliac crest bone graft, and 2 had pain necessitation hardware removal. All 4 of these patients had no further problems at final follow-up evaluation. There was no statistically significant difference between the arthroscopic debridement alone cohort and the arthroscopy/ulna-shortening subgroup relative to ulnar variance or incidence of associated lunotriquetral ligament tears. On the basis of these findings the authors recommend a 2-mm-long ulna-shortening osteotomy for patients whose previous arthroscopic debridement for central or nondetached peripheral TFCC was unsuccessful in eliminating ulnar-sided wrist pain.

Adult↗