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Biomedical subjects

A P Solov'eva

Publications and source records attributed to A P Solov'eva.

At least 19 recordsLinked to original sources
PubMed1986

[Effect of corticosteroid therapy on the survival of patients with idiopathic dermatomyositis].

The 5- and 10-year survival rates of all 114 patients with primary DM were 89 and 81%, respectively. Significantly lower survival rates were noted in the patients receiving late and inadequate therapy. Corticosteroid therapy radically changed the outcome of DM, mainly due to early diagnosis and adequate therapy. A stable remission with preserved working ability was obtained in 40.4% of the patients, a complete cure of DM in 33.3%.

Adolescent↗
PubMed1985

[Fever masks of malignant tumors].

During 5 years, the authors followed up 129 patients referred to the clinic with a diagnosis of fever of unclear genesis. In 36.4% of cases, fever masked malignant neoplasms. Hyperthermia was ahead of the emergence of the symptoms of a tumor (maximally up to 12 years), dominated or was the only symptom for a time being. However, in most cases it combined with other paraneoplastic masks (rheumatic, hematological, hepatological, etc), was resistant to the treatment and disappeared after radical treatment.

Adolescent↗
PubMed1985

[Paraneoplastic syndromes in bronchogenic carcinomas].

During 5 years the authors followed up 35 patients with bronchogenic carcinomas. Of these, 34.3% had diverse paraneoplastic manifestations. The paraneoplastic reactions determined by ectopic production of different hormones and other substances as well as so-called "masks" of the systemic diseases are reviewed. An attempt is made to specify the basic mechanisms of the pathogenesis of each paraneoplastic sign.

Aged↗
PubMed1975

[Cardiovascular pathology in dermatomyositis].

Among 110 patients with dermatomyositis cardiovascular pathology was found in 77, and only in 37 of them it was attributable to the underlying pathology. In all of these patients myocardial lesions were found, that manifested themselves most frequently by non-specific ECG changes. Cardiac insufficiency and arrhythmias were revealed less frequently, mainly during exacerbations of the pathological process. Only in one patient endocarditis was diagnosed, and in two others elements of chronic cor pulmonale due to pneumonitis. In 18 patients signs of moderate myocardial dystrophy developed after a long-term therapy with corticosteroid hormones. A study of the central haemodynamics in 20 patients with dermatomyositis revealed a tendency towards a hyperkinetic state of the circulation in those patients who had the most sereve muscle syndrome. Angioscopy of the bulbar conjunctiva revealed the changes that persisted even during the remission period, achieved by means of active steroid therapy.

Adolescent↗