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Biomedical subjects

A P Leach

Publications and source records attributed to A P Leach.

2 recordsLinked to original sources

Assessing competence in finding and reporting abnormal morphologic features while scanning peripheral blood smears.

OBJECTIVE: To develop a competency assessment tool to determine if technologists are detecting and reporting clinically significant findings on blood smears and to identify if proficiency improves through education using a video presentation. DESIGN: Combination of nonequivalent pretest-post test control group and modified time-series design. SETTING: A large medical center in Southern Louisiana. PARTICIPANTS: All shifts of technologists working in the Core Hematology and Special Hematology Laboratories. This sample is a nonprobability sample of convenience. INTERVENTION: A thirty-five minute videotape on the standardization of RBC morphology. MAIN OUTCOMES MEASURE: Develop a method for measuring competency of technologists who perform scans of peripheral blood smears as part of the automated white blood count differential process.

Blood Cells↗

Apoptosis: molecular mechanism for physiologic cell death.

Molecular biology is fast becoming the wave of the future in research as well as in the clinical laboratory. This trend toward determining cell function at this level is opening up doors to new techniques in evaluating and diagnosing such diseases as AIDS and cancer. This article focuses on apoptosis or programmed cell death, its morphological characteristics, its comparison to necrosis, its occurrence in development and homeostasis of multicellular organisms, its genetic regulation, and its involvement in diseases.

Acquired Immunodeficiency Syndrome↗