A new use of a 'Minitrach' introducer.
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Biomedical subjects
Publications and source records attributed to A P Daykin.
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The effects of intravenous morphine (10 mg/70 kg) on the ventilatory response to CO2 were studied in two groups of subjects, young (18-29 years) and old (66-85 years), prior to elective surgery. In both groups morphine caused a significant depression of respiration as judged by a reduction in the slope of the CO2 response curve, a reduction in the calculated ventilation at an end tidal CO2 tension of 7.3 kPa, a rise in resting end tidal CO2 and a rise in the CO2 threshold. There were no significant differences between the two groups in the changes produced by the drug, suggesting that acute respiratory depression after a single intravenous injection of morphine is similar in old and young people.
Twenty seven insulin-dependent diabetic patients received a continuous intravenous infusion of an insulin-glucose-potassium solution whilst undergoing elective surgical or obstetric procedures. The dose of insulin was adjusted according to blood glucose values. It was concluded that the regimen is safe and simple to manage and should result in good control of blood glucose levels.
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