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Biomedical subjects

A Ota

Publications and source records attributed to A Ota.

143 records · Page 8Linked to original sources
PubMedDate not supplied

Effects of meal intake on the flow velocity in the superior mesenteric artery: evaluation with 2D phase mapping MRI.

OBJECTIVE: Reliable results in MR flow measurements have been reported in humans. The current study was performed to evaluate the effects of a meal intake on the flow velocities in the superior mesenteric artery (SMA) and aorta by using 2D phase-mapping MRI. MATERIALS AND METHODS: A constant flow phantom generating 0-150 cm/s of flow velocities was constructed to evaluate the accuracy of MR flow measurements. Eleven healthy volunteers underwent serial MRI once before and three times after a mixed meal intake (700 kcal). RESULTS: Reliable MR flow measurements were validated in the constant flow phantom. In the healthy volunteers, the SMA and aorta had triphasic flow velocity waveforms in one cardiac cycle. Ingestion of a mixed meal increased flow velocities in the SMA. Peak velocities were observed at 20 min after the meal. The aortic flow velocities were unaffected by the meal. CONCLUSION: A 2D phase-mapping MR technique is feasible to evaluate the SMA and aortic flow velocities. Evaluation of the flow velocities in the SMA may contribute to understanding intestinal as well as hepatic conditions in humans.

Adult↗
PubMedDate not supplied

Criterion-related validity of diagnostic criteria for alexithymia in a general hospital psychiatric setting.

BACKGROUND: The diagnostic criteria for alexithymia (DCA) was proposed by Fava et al. in 1995. The purpose of this study was to examine the criterion-related validity of the DCA in a general hospital psychiatric setting. METHODS: The subjects included 126 outpatients with psychiatric disturbance. The severity of alexithymic characteristics was assessed using the DCA and Beth Israel Hospital Psychosomatic Questionnaire (BIQ). Two Japanese versions of the 26-item Toronto Alexithymia Scale (TAS-26) and Minnesota Multiphasic. Personality Inventory-2 (MMPI-2) were administered. RESULTS: The DCA had relatively high sensitivity and specificity, indicating adequate discriminant validity. The discriminant validity of the DCA was also supported by significant associations of the DCA with the TAS-26 and MMPI-2. These results indicate that when used for screening, the DCA has adequate criterion-related validity. CONCLUSIONS: The DCA may be clinically useful in a general hospital psychiatric setting.

Adolescent↗
PubMedDate not supplied

Hypoxic-ischemic tolerance induced by hyperthermic pretreatment in newborn rats.

OBJECTIVE: We investigated the effect of hyperthermic pretreatment 24 hours before hypoxic-ischemic exposure on neuronal cell damage in 7-day-old rats. METHODS: Newborn rats were separated on postnatal day 7 into two groups: 1) preheated (those exposed to 2 hours of hyperthermic pretreatment at 42-43C) (n = 29), and 2) nonheated (n = 20). At 24 hours after the hyperthermic stress, rats from both groups were subjected to left carotid artery ligation followed by 2 hours of hypoxia (8% oxygen/92% nitrogen) at 33C. All rats were killed 1 week after hypoxia-ischemia, and brains were extracted for histologic study. A different group of 7-day-old rats (n = 8) was placed in the same hyperthermic environment as mentioned above for 2 hours, and 24 hours after heat exposure brains were extracted for immunohistochemistry of heat-shock protein 70. RESULTS: The total incidence of hypoxic-ischemic brain damage significantly decreased in the preheated group (12 of 25 [48%]) compared with the nonheated group (17 of 20 [85%]; P < .03). The induction of immunoreactive heat-shock protein 70 was observed mainly in glial and vascular endothelial cells and, in a lesser amount, in neuronal cells of the cerebral cortex and hippocampus. CONCLUSION: Incidence of hypoxic-ischemic brain damage is consistently reduced by 2 hours of hyperthermic pretreatment in 7-day-old rats.

Animals↗
PubMedDate not supplied

[Splenic hydatid cyst].

The localization of hexacanth embryo at spleen level is quite rare, although, in frequency order, it is the third affected organ after liver and lung. The infestation of the spleen usually takes place by arterial route after the parasite has passed through the two other filters, hepatic and pulmonary. The retrograde venous route, which avoids the liver and lung, is also considered. The diagnosis of splenic echinococcosis is made with the clinical, epidemiological and laboratory findings. The treatment is surgical, consisting, most commonly, in splenectomy; the anastomoses of splenic hydatid cysts with the digestive tube are indicated only in those cases with peculiar evolutive forms; cystotomy, with removal of the content and drainage of the remnant cavity, surgery performed either on abdominal or lumbar route, is the method of choice in the suppurated cysts which fix, by adherences, the spleen to its lodge.

Adult↗
PubMedDate not supplied

[A giant cancer of a gastric diverticulum].

An observation is presented, of a female patient aged 62 years with a large abdominal tumour. Clinical and para-clinical examinations could not establish the organic origin of the formation. Surgery disclosed a giant tumour developed in a gastric diverticulum situated under the cardia. The patient had suffered for a long time with gastric symptoms and her antecedents included upper digestive haemorrhage which was attributed to gastric ulcer according to radiological examination. In retrospect it was established that the disturbances were determined by a gastric diverticulum, complicated by haemorrhage and which later on had become malignant. In spite of its extraordinarily large size the tumour was removed by total gastric resection, in an attempt to treat radically the cancer.

Carcinoma↗
PubMedDate not supplied

[Voluminous malignant nonsecreting tumors of the adrenal cortex ruptured in thoracic-lumbar injuries].

Based on two cases of nonsecreting malignant adrenal tumors the authors make some clinical and therapeutical considerations. These tumors are rare, have a longer evolution without significant clinical manifestations, may reach considerable size and may become complicated, most frequently by intratumoral hemorrhages and necroses, which usually favour an infection, and more rarely by their rupture. The diagnosis is based on the clinical and laboratory findings. The treatment is surgical, associated with chemotherapy and radiotherapy. The survival interval is long, sometimes exceeding 10 years.

Adrenal Cortex Neoplasms↗
PubMedDate not supplied

[Cancer of the rectosigmoid junction].

The authors present a statistics on 32 cases of proctosigmoid junction cancer and discuss diagnostic and management aspects. This localization of the colorectal cancer has certain characteristic features, among which most important are its severe complications. The treatment of choice is the high anterior proctosigmoid resection with restoration of digestive passage, with or without colostomy. In the complicated cases the interventions will be performed in two or even three stages. Hartman's surgery is also indicated in the complicated cancers and in the compromised patients. The postoperative mortality remains high.

Colectomy↗
PubMedDate not supplied

[The management of acute complications in gastric cancer].

Forty-five acute complications (perforations and upper digestive hemorrhages) occurring in 650 admitted and operated gastric cancer patients were investigated. Despite all problems raised by these complication (gastric cancer, most commonly in advanced stages and invading the neighboring areas, the poor general condition of the patients, age-related deficiencies), the authors regard the removal of the complicated tumor and sometimes wide gastrectomy (the concomitant resection of gallbladder, spleen, atypical liver resection transverse colon resection) as the only solution for the complications, the postoperative complications and early recurrences of the complications as well as mortality rate being at the same time reduced.

Acute Disease↗