Biomedical subjects

A Ostman

Publications and source records attributed to A Ostman.

57 records · Page 4Linked to original sources

PubMed1987

Purification of the receptor for platelet-derived growth factor from porcine uterus.

The receptor for platelet-derived growth factor has been purified to homogeneity on a large scale from porcine uterus. The purification procedure utilizes solubilization of uterus membranes by Triton X-100, followed by sequential chromatographies on wheat germ agglutinin-Sepharose, fast protein liquid chromatography Mono-Q, and anti-phosphotyrosine-Sepharose. About 160 micrograms of homogeneous and functionally active 170-kDa receptor could be purified from 5 kg of uterus tissue. The pure receptor responded to platelet-derived growth factor stimulation by autophosphorylation, indicating that the receptor has a kinase domain as an integral part of the molecule. A rabbit antiserum was produced against the pure receptor, which specifically recognizes the intact 170-kDa receptor.

Animals↗

PubMed1986

Stereophotogrammetry in the evaluation of the treatment of scoliosis.

A previously existing X-ray stereophotogrammetric method which allows the measurement of simultaneous changes in all components of a scoliotic deformity was developed without the use of invasive methods or skeletal markers. In order to evaluate the changes in rotation and lateral deviation of the scoliotic curve following treatment with the Boston brace, this method was applied to 31 patients suffering from idiopathic scoliosis. The derotational effect of the brace averaged 14 degrees (0-38 degrees) in 21 patients remaining after rejection of those whose radiographs were of inadequate quality. The accuracy, however, was not acceptable because of frequent gross errors due to the poor quality of the radiographs. Image interpretation may be improved by a suggested technique of enhancement based upon a computer program for figure restauration and border detection.

Adolescent↗

PubMed1986

The effect of a device for transverse traction on vertebral rotation in surgery for scoliosis as studied by X-ray stereophotogrammetry.

The effect of a device for transverse traction (DTT) on vertebral rotation in surgery for scoliosis has been analysed with an X ray stereophotogrammetric method in 17 patients. Six of them underwent conventional Harrington rod instrumentation and eleven patients received additional treatment with the DTT. The DTT exerted a positive effect on vertical rotation at the apex, and derotation average 10 degrees as compared with 5 degrees in the group in whom the device was not used.

Adolescent↗