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Biomedical subjects

A Orsini

Publications and source records attributed to A Orsini.

At least 19 recordsLinked to original sources
PubMed1992

[Clinical development of beta-thalassemia-sickle cell anemia apropos of 36 cases].

Hematological and clinical features of 36 mainly Algerian patients with S-beta thalassemia are reported. These data, compared with those reported in the literature, showed a higher prevalence of aseptic necrosis and gall stones, probably related to the large predominance of S-beta zero-thalassemia (30 cases) and a long (14 years) median follow-up period.

Adolescent↗
PubMed1979

[The use of intravenous gamma globulins in pediatrics].

In pediatrics, intravenous Gamma Globulin therapy is extremely valuable when combined with other antimicrobial therapy or when employed on its own especially in cases of viral infection. The use of the intravenous route allows the injection of large amounts of drug, intramuscular injections, which are often counter-indicated in children, particularly in children suffering from malignant blood dyscrasias, are thus avoided. Furthermore with the intravenous route, a high blood titre of gamma globulins is achieved immediately and the treatment can be maintained as long as necessary. The tolerance to this drug, in our experience, at least with the preparation used, was found to be excellent in the vast majority of cases. These preparations ought to be widely employed in all of the serious digestive disorders and in paediatrics.

Bacterial Infections↗
PubMed1978

[Hemoglobin oxygen affinity in children on chronic hemodialysis].

We have studied the changes induced by hemodialysis in the blood oxygen affinity in a group of 8 children with chronic kidney failure. Before dialysis: the affinity was low - P50 (7.40) = 28,3 Torr. Such a decreased affinity could explain in part why the important anemia (2 million RBC on average) observed in these patients was well tolerated. The observed decrease in hemoglobin oxygen affinity was attributed to an increase in 2-3 diphosphoglycerate (2-3 DPG) concentration, resulting from a high level of inorganic phosphates. After dialysis: the plasmatic pH increased markedly (7.52) with a consequent increase in the blood oxygen affinity in vivo (Bohr effect). No substantial change in 2-3 DPG concentration on P50 (7.40) occurred during hemodialysis.

Adolescent↗
PubMed1978

[Hemoglobinoses].

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Amino Acid Sequence↗