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Biomedical subjects

A Okamura

Publications and source records attributed to A Okamura.

At least 163 records · Page 9Linked to original sources
PubMed1984

Clinicopathological study on the relationship between serum-CEA and tissue-CEA of resected lung cancer cases.

The clinicopathological correlation between serum-CEA (s-CEA) and immunohistological tissue-CEA (t-CEA) was studies on 63 cases of operated lung cancers. T-CEA was examined by peroxidase anti-peroxidase (PAP) method. T-CEAs were detected in 36/39 cases (92.3%) of adenocarcinoma, 16/16 cases (100%) of epidermoid carcinoma, 2/5 cases (40%) of large cell carcinoma, and 1/3 case (33.3%) of small cell carcinoma. T-CEAs in adenocarcinoma and large cell carcinoma with mucin exhibited moderate to strong reactivity with diffuse distribution, and also s-CEA of these cases indicated high levels. On the contrary, in epidermoid carcinoma t-CEAs showed a weak reactivity with focal distribution, and s-CEAs also demonstrated low levels. In adenocarcinoma it was suggested that the more cancers were differentiated, the more t-CEA and s-CEA were increased, and about two third of cases showed a balance between t-CEA and mucin content in cancer tissue. S-CEAs were not correlated with the size of the primary lesion or the extent of lymph node metastasis, but with the histological types, i.e. high levels of s-CEA in adenocarcinoma and large cell carcinoma with mucin.

Adenocarcinoma↗
PubMed1983

Generalized fibrosis associated with pulmonary asbestosis.

An autopsy case of pulmonary asbestosis with fibrosis of various organs was reported. Pulmonary carcinoma and glomerulonephritis were complicated. Asbestos bodies (ABs) and fibers (AFs) were identified in the organs with fibrosis such as the lung, liver, kidney, heart, and thyroid gland by electron microscopy and digestion method. Moreover, we identified AFs in the spleen by electron microscopy which had been resected due to idiopathic portal hypertension six years previously. It is suggested that AFs can be transported to various organs and persist for a long period of time to cause pathological changes there.

Asbestosis↗