Search PubMed⌕ Search

Biomedical subjects

A Novick

Publications and source records attributed to A Novick.

At least 55 records · Page 3Linked to original sources
PubMed1985

Medial agenesis associated with multiple extracranial peripheral and visceral arterial aneurysms.

Developmental abnormalities consisting of focal absence of the arterial media have been implicated in the formation of the arterial aneurysms commonly observed in the intracranial cerebrovascular system. However, this observation has rarely been associated with visceral or peripheral arterial aneurysm formation. This article describes the experience with two patients having multiple peripheral and visceral arterial aneurysms with histologic findings previously observed only in intracranial, saccular berry aneurysms and in one patient with an isolated common carotid artery aneurysm. The two patients described herein had no clinical or angiographic evidence of cerebrovascular aneurysm formation. Light and electron microscopic histologic studies revealed complete focal absence of the arterial media in the region of aneurysm formation. No clinical or laboratory evidence of associated collagen-vascular disease was demonstrated. The patients were successfully managed with segmental resection and grafting of symptomatic, expanding, or large aneurysms. The necessity for an aggressive search for associated aneurysms as well as the need for long-term follow-up when histologic evidence of medial agenesis is demonstrated in association with arterial aneurysm formation are emphasized.

Aneurysm↗
PubMed1985

Quarantine and AIDS.

Explore the source record for details and available documents.

Acquired Immunodeficiency Syndrome↗
PubMed1984

Renal transplantation of patients on chronic peritoneal dialysis.

A retrospective review of patients transplanted from peritoneal dialysis was performed to assess the risk of this form of dialysis for patients awaiting renal transplantation. Eighteen transplants have been performed in 16 patients, ages 6 to 57 years, undergoing chronic peritoneal dialysis over the past 4 years. Sixteen were from cadaver donors, and two were from living related donors (LRD). The patients had been undergoing intermittent peritoneal dialysis or continuous ambulatory peritoneal dialysis (CAPD) using permanent silastic catheters, from five days to 4 years. No patient had clinical evidence for peritonitis at the time of transplantation. The peritoneal catheter was removed at the time of transplant in all cadaver donor recipients without complication. One recipient of a LRD kidney had the catheter removed two days prior to transplant. Cultures of the catheter were sterile in 16 cases. Two patients had positive peritoneal catheter cultures at the time of transplant but were treated with appropriate antibiotics and never developed clinical peritonitis. Fourteen transplants had postoperative fevers. No definite source was found in 13; one had fever in relation to acute graft rejection. The fevers resolved in all patients either spontaneously or subsequent to therapy. Other complications were similar to those seen in patients transplanted from hemodialysis. Hemodialysis was performed as needed pretransplant and posttransplant using a temporary femoral vein catheter or arteriovenous fistula without complication. Nine patients are alive with a functioning kidney 1 to 36 months posttransplant (mean 17 months). Six transplants rejected (five patients), and one failed secondary to renal vein thrombosis. Two patients died posttransplant, one after a cerebrovascular accident, and one due to an unknown cause 1 month postnephrectomy for rejection. In conclusion, patients undergoing chronic peritoneal dialysis can be successfully transplanted without a significant incidence of complications related to their peritoneal dialysis.

Adolescent↗
PubMed1982

The treatment of sexual phobias: the combined use of antipanic medication and sex therapy.

During the past 20 years, there has been described a group of profoundly anxious and phobic patients, who are not amenable to psychological forms of treatment or to the major and the minor tranquilizers, but who respond dramatically to tricyclic and MAO inhibitor medication. The separation of this drug-responsive syndrome from other anxiety disorders constitutes a major advance in psychiatry. This paper discusses the implications of these findings for the treatment of psychosexual disorders. To illustrate the hypotheses and discussion, the case histories of three patients with sexual phobias are described. All had been treatment failures with sex therapy and psychotherapy but responded to a combination of tricyclic medication and sex therapy which was modified to accommodate the special needs of sexually phobic patients.

Adult↗
PubMed1980

Late ureteral obstruction and hematuria from de novo angiosarcoma in a renal transplant patient.

A patient is described with a long-term functioning renal allograft who presented with ureteral obstruction and hematuria from an angiosarcoma. The diagnosis of ureteral obstruction was established preoperatively with computerized tomography guided anterograde pyelography. This represents the first documented case of an angiosarcoma occurring de novo in a renal allograft recipient. Continued awareness is needed of the increased risk of malignancy following transplantation.

Adult↗
PubMed1979

Impaired renal allograft function: a comparative study with angiography and histopathology.

We reviewed 47 renal transplant recipients who had undergone angiography and transplant biopsy to evaluate impaired allograft function. Angiographic criteria for rejection were seen in all allografts with hyperacute rejection, accelerated rejection and chronic rejection, and in 13 of 17 allografts with acute cellular rejection. Angiography was normal in allografts with vasomotor nephropathy or transplant glomerulopathy. Angiography is an accurate method for the diagnosis of most causes of post-transplant dysfunction.

Biopsy↗
PubMed1978

Elemental diet as an adjuvant for patients with locally advanced gastrointestinal cancer receiving radiation therapy: a prospectively randomized study.

Thirty patients with locally advanced, nonresectable, nonmetastatic cancer in the peripancreatic region, stomach and colorectum-anus, to be treated with radiation therapy with or without adjuvant chemotherapy, were randomized to receive standard diet and either usual between-meal feedings or 300 calories tid of a high nitrogen elemental diet. Although weight loss associated with radiation therapy was not significantly reduced in those receiving the nutritional supplement, delayed hypersensitivity skin test responses tended to improve in patients receiving the elemental dietary supplement and to deteriorate in controls. Planned radiation therapy was completed in all nutritionally supported patients. One control patient expired shortly after treatment was halted abruptly, and three other control patients required rescue by total parenteral nutrition.

Energy Intake↗