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Biomedical subjects

A Nori

Publications and source records attributed to A Nori.

35 records · Page 2Linked to original sources

[Primary malignant tumor of the liver in children].

Primary malignant tumours of the liver in children are rare. They occur in more than 50% of cases before the age of 2 years. The clinical signs are very often limited to a large mass in the right hypochrondrium. A search for alphafoetoprotein and arteriography are the most useful investigations for diagnosis. The pathology leads one to distinguish hepatoblastomas and hepatocarcinomas. The prognosis in these tumours remains poor for, in spite of progress in liver surgery, a cure is rarely possible. It is important for doctors to recognize the existence of this tumour pathology in order to give a chance for surgery to succeed in these young children. To illustrate this, 5 cases from Besançon are reported here.

Adolescent↗

Is normal beta-hCG regression curve helpful in the diagnosis of persistent trophoblastic disease?

OBJECTIVE: The aim of this study was to evaluate the probable usefulness of normal beta-human chorionic gonadotropin (beta-hCG) regression curve in the diagnosis of persistent trophoblastic disease (PTD). METHODS: A log-value regression curve was developed from the means and 95% confidence limits of serial weekly serum beta-hCG titers of 43 patients with uneventful complete hydatidiform moles and 14 patients, who were previously confirmed as PTD. RESULTS: All 14 PTD patients (100%) had abnormal values, beyond normal range, within 4 weeks. beta-hCG was in its upper values, compared to normal regression curve at 2.29 +/- 0.19 weeks. This was earlier than plateau or rise detection at 4.21 +/- 0.33 weeks (P < 0.001). Within 3 weeks of evacuation, 13 of 14 (92.86%) PTD patients' beta-hCG values exceeded the normal range, whereas only six of 14 (42%) showed a rise or plateau. CONCLUSION: Our finding indicates that the normal beta-hCG regression curve may be useful for quicker detection of PTD than the plateau or rise of level.

Adult↗

[Dental pathology in malformation syndromes: the methodology and intervention timing].

Due to the complexity and potential vulnerability of the cranio-facial area (skull, face, nose, oral cavity), specific alterations of this region are associated to genetic and acquired malformations in a high percentage of cases (75%). Often, the specificity and extent of the pathological symptoms occurring in the cranio-facial area are the dominant aspects of the malformation syndrome according to which it is classified. When multiple development anomalies in a newborn suggest the existence of a syndrome, the patient should be placed in the care of a pediatrician, who, together with a team of specialists, will follow the child and face the various problems related to the syndrome at the right time. The frequent marked involvement of the craniofacial area in malformation syndromes suggests the opportunity of a specialist methodology to standardize odontostomatological therapy.

Abnormalities, Multiple↗