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Biomedical subjects

A Nicolai

Publications and source records attributed to A Nicolai.

65 records · Page 4Linked to original sources
PubMedDate not supplied

Partial Klüver-Bucy syndrome arising from a multicentric glioblastoma: anatomo-clinical study of a case with unusual involvement of CNS.

The authors describe the case of a patient showing clinical symptoms consistent with a partial Klüver-Bucy syndrome. CT-scan, macroscopic and histological findings showed the presence of a multicentric glioblastoma with almost exclusive involvement of subcortical gray nuclei and white matter. The possible anatomo-clinical correlations of these unusual locations in KBS are discussed. In addition, the authors emphasize that KBS can arise not only from lesions located in the temporal cortex and/or amygdala, but also from strategically located subcortical lesions particularly involving striatal nuclei and subcortical white matter in the insular area.

Agnosia↗
PubMedDate not supplied

Hemichorea-hemiballism and anosognosia following a contralateral infarction of the caudate nucleus and anterior limb of the internal capsule.

The authors describe a patient who experienced the sudden occurrence of hemicorea-hemiballism on the left side of the body and the contemporary agnosia of it. An unenhanced CT-scan disclosed an ischemic lesion involving the head of the caudate nucleus and of the anterior limb of the internal capsule of the contralateral hemisphere. The authors discuss the possible pathophysiologic mechanisms explaining the rare association of these two symptoms and suggest that the involvement of the pyramidal tract in the internal capsule usually does not allow hyperkinesis to manifest itself.

Aged↗
PubMedDate not supplied

Quadriceps myopathy: report of a late onset sporadic case.

The Authors describe the case of a 44 year-old man whose familial and personal histories were negative for muscular diseases. The patient complained slowly progressive wasting and weakness localized to the quadriceps muscles. The bioptic study of the gastrocnemius and the quadriceps showed dystrophic changes, confirming that muscular dystrophy closely localized to quadriceps is of rare occurrence. Muscles other than quadriceps can often be involved by the same pathology even if the clinical signs continue to be localized to the quadriceps muscles for many years.

Adult↗
PubMedDate not supplied

[Value of visually evoked potentials in lesions of the optic nerve caused by a mucocele].

Mucoceles originating in accessory paranasal sinuses with orbit involvement are quite rare. The authors describe two cases of mucoceles, revealed by CT-Scan, the first in the ethmoid-sphenoidal-maxillary sinuses and the other in the ethmoid-frontal sinuses respectively. In both cases Visual Evoked Potentials were most important for assessing optic nerve involvement. They were also useful to check post surgical recovery. These case reports emphasize that early diagnosis of mucoceles involving the optic nerve is very important because prompt surgical treatment may lead to recovery of visual disturbances.

Aged↗
PubMedDate not supplied

[Clinical considerations and EEG-CT correlations in lacunar infarcts].

56 cases of lacunar stroke were reviewed retrospectively. The patients showed a clinic picture which could be classified within nine of the lacunar syndromes recognized by Fisher. The localization of the lacunes was considered with respect to the clinical symptoms and the characteristics of the EEG and the TC and their different correlations were examined. The EEGrafic patterns of the lacunar strokes with normal TC were compared with those showing an altered one. Our study suggests that the absence of EEGrafic alterations may be a useful characteristic for the diagnosis of lacunar stroke, even when TC is normal. No significant correlations were found between the alterations of the EEG and the dimensions and/or localizations of the lacunes, as well as between the type of EEG (localized-wide-spread) and the size (large-small) of the lacunar infarcts.

Aphasia, Broca↗
PubMedDate not supplied

Peripheral nerve vasculitis: a clinico-pathological study.

The clinico-pathological findings of 20 nerve biopsies consecutively performed at the neuropathological laboratory of Verona University Hospital were reviewed in order to establish the most important clinical manifestations of peripheral nerve vasculitis and to determine the role of biopsy in corroborating the diagnosis. Dystal sensori motor polyneuropathy was the most frequent clinical manifestation, confirming previous clinico-pathological studies and suggesting a more widespread pathological process than usually supposed. The biopsy was the basis of the diagnosis since it established or substantially modified the clinical diagnosis. Therefore we suggest that in cases with suspected vasculitis of the peripheral nerve the biopsy makes a useful contribution to diagnosis.

Adult↗