Percutaneous transluminal angioplasty: preliminary results.
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Biomedical subjects
Publications and source records attributed to A Nevelsteen.
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During a 15-year period, the aortofemoral Dacron graft was used for revascularization of 615 limbs in 352 patients, with an overall operative mortality rate of 5.1% and a cumulative 10-year patency rate of 62%. The late complication rate was 27%, with late thrombosis being by far the most frequent complication (24%). Among several factors responsible for late occlusion, the presence of trifurcation disease and the site of the femoral anastomosis are by far the most important. Our procedure of choice for a thrombosed graft limb is thrombectomy and profundaplasty, which give a long-term patency rate of 68%.
Percutaneous transluminal atherectomy with the Simpson atherectomy catheter was performed in 10 patients with 14 severe atheromatous stenoses of the femoropopliteal arteries. Removal of plaque material with restoration of vessel patency was successful in all patients without complication. Further clinical follow-up will have to determine whether the recurrence rate of stenoses will be lower with this method than with conventional balloon angioplasty.
Fibromuscular dysplasia is a multifactorial arteriopathy most commonly affecting the renal and carotid arteries. In this report we present a case of visceral artery involvement, causing occlusion of the superior mesenteric artery and celiac trunk and resulting in visceral ischemia. Treatment consisted of superior mesenteric artery reimplantation. Visceral artery FMD can present as occlusive or aneurysmal disease and treatment depends on patient characteristics and symptoms.
A patient with a paraprosthetic-sigmoid fistula following complicated aortic abdominal surgery is reported. Computed tomography confirmed the diagnosis by demonstrating inflammatory tissue around the left limb of the prosthesis in close contact with the sigmoid.
The authors describe three patients who developed a blue toe syndrome after initiation of oral anticoagulant therapy. Based on these observations and data in the literature, they discuss a possible relationship. They conclude that the vascular surgeon should be aware of this possibility and that oral anticoagulants should be used very carefully in the "medical" management of cholesterol embolization.
Graft limb patency was studied retrospectively in a consecutive series of 912 patients (1605 limbs), who received an aorto(bi)femoral Dacron graft for occlusive disease over a 25 years period (1963-1987). The mean follow-up for the series was 5.35 years (range 1 month to 23 years) and 18.5% of the patients were followed for at least 10 years. Primary patency decreased progressively to 83% at 10 years and 77% at 15 years. It was significantly improved to 90% (at 10 years) and 84% (at 15 years) by means of operative thrombectomy (secondary patency). Factors influencing patency (univariate analysis) were (1) concomitant femoropopliteal occlusive disease, (2) the site of the femoral anastomosis and (3) the date of the operation. Multivariate analysis in relation to the femoral anastomosis stressed the importance of profunda femoris artery disease and the date of operation. It is concluded that the negative effects of concomitant superficial femoral artery disease may be completely relieved by an adequate profundaplasty. Furthermore the substantial progress, we documented over the years of the study, supports our view that aortofemoral reconstruction may also be offered as the solution of choice to patients with milder forms of claudication.
The authors describe the technique of the supraceliac aorta-to-femoral artery bypass graft. This type of reconstruction is presented as a possible alternative in patients with relative contraindications to direct approach of the infrarenal abdominal aorta.
The authors report about a patient who presented three weeks after reconstruction of an infrarenal aortic abdominal aneurysm a rupturing aneurysm of the gastroduodenal artery. The symptoms and method of treatment of this rare condition are described on the basis of a literature survey.
Between 1978 and 1988 133 extra-anatomical grafts were performed in patients presenting with aorto-iliac occlusive disease. These series include 50 cross-over grafts, 46 axillofemoral and 37 axillobifemoral grafts. The indication for operation was acute ischemia in 26.4%, claudication in 9.7% and limb salvage in 63.9% of cases. Perioperative mortality rate was 10.4%. The early patency rate decreased from 92% after cross-over grafting to 86% in the axillofemoral series and 8% of the patients needed a major amputation in the immediate postoperative period. With a mean follow-up of 32 months, 62% of the patients died within 5 years of the operation, 54% of deaths being due to cardiovascular complications. The 3-years patency rate decreased to 78% after cross-over grafting and 49% after axillofemoral grafting. The 3-year limb salvage rate decreased to 89% and 75% respectively. Although our results are definitely less favourable than those of direct aortofemoral grafting, they seem to support the further use of the cross-over graft in patients with unilateral occlusive disease. Axillofemoral grafting on the other hand should be preserved for limb saving reconstructions in high risk conditions.
A prospective study was undertaken to evaluate the clinical and hemodynamic effects of aortofemoral Dacron reconstruction in patients with multilevel disease (i.e. aortoiliac and femoropopliteal occlusive disease). Thirty nine patients underwent, apart from clinical evaluation, segmental plethysmography and Doppler pressures before operation, immediately after operation and again at 3 and 6 months. All patients improved by the reconstruction, but 12 (31%) continued to complain of disabling claudication during normal daily activities. The mean ankle pressure and thigh pressure index improved by 37.5%. This was accompanied by a decrease of peak flow time, an increase of peak flow and an improved recovery during reactive hyperemia. Furthermore an additional significant rise of the ankle pressure index was noted between 3 and 6 months. Continuing claudication was always associated with both initial and late hemodynamic failure (the criterium for hemodynamic success was defined as an increase of the ankle pressure index with more than 0.1). Hemodynamic success resulted unvariably in clinical success. However 4 patients were clinically symptomfree, although they had to be classified as hemodynamic failures. It is concluded that a significant number of patients fail to obtain complete relief after proximal reconstruction. Preoperative hemodynamic studies may provide additional information, but hemodynamic and clinical results do not always correlate with each other.
We report on the results of combined carotid endarterectomy and coronary artery bypass grafting in 82 patients. Vascular pathology was severe in these cases: 94% of patients had extensive multivessel coronary artery disease, 29% had unstable angina, 30% had severe left main stem stenosis and all patients had hemodynamically significant stenosis of at least one carotid artery, 13% had an additional occlusion of the contralateral internal or common carotid artery and 26% had severe bilateral carotid artery stenosis. The carotid lesion was asymptomatic in 64% of cases, 24% of the patients experienced previous transient cerebral ischemia and 12% of the patients had a history of completed stroke. Hospital mortality was 7.3%. Neurological deficit occurred in 7.3% but functional impairment was not permanent. Late results have been obtained for 76 survivors at a mean postoperative interval of 29 months. Five year life table survival rate was 86%. Follow-up showed that 3 patients (4%) have died and that 3 patients (4%) experienced a late neurologic event (one TIA; two strokes) but none of these events involved the cerebral cortex on the side of the carotid endarterectomy. The cumulative 5 year stroke free survival rate is 91%. We conclude that combined carotid endarterectomy and coronary artery bypass grafting can be done with an acceptable mortality rate in these critically ill patients and that the postoperative incidence of neurological events is low.
The study was performed to evaluate the diagnostic value of Indium-111-leukocytes scintigraphy in arterial prosthetic infection. Scintigrams were performed in 19 patients in two groups. Group A consisted of 11 patients, where ten days after uncomplicated graft implantation, an Indium-111-scintigraphy was performed. Group B consisted of 8 patients, where we suspected an infected arterial graft. In group A we had one false-positive scan and in group B one false-negative scan. This gives an accuracy of 89%, a sensitivity of 87% and a specificity of 90%. These results indicate that Indium-111-leukocytes scintigraphy is a favourable test to detect a vascular graft infection.
The Authors describe a patient, in whom an infected aortobifemoral Dacron prosthesis was successfully replaced by an autogenous venous graft. A review of the literature is presented and it is concluded that autogenous reconstruction of the infected field represents a feasible alternative to extra-anatomical revascularisation in the treatment of selected patients with vascular prosthetic infection.
Fibromuscular dysplasia of external iliac artery in a 30 year old woman was treated by endoluminal angioplasty with excellent results: claudication symptoms were absent during a 6 month follow up.
The authors present a series of 98 patients, who underwent an aorto-ilio-femoral endarterectomy according to the technique of LeVeen. The operative mortality was 1% with an adjusted early patency rate of 99%. For a total of 52 documented cases, erectile function was lost in 25%. Ejaculatory disorders were seen in 35 patients. With a mean follow-up period of 22 months (range 1 to 60 months) there were no occlusions in the aortoiliac group. Patency in the aortofemoral group decreased to 92.5% after 4 years. It is concluded that the results support continued use of the reported technique. A longer period of follow-up however is recommended to define its exact role in reconstructive surgery for aortoiliac occlusive disease.
The authors describe four cases of arterial damage secondary to the use of the Fogarty balloon catheter. A review of the literature is presented and it is concluded that the number of complications after balloon catheter thrombectomy is generally underestimated. The associated morbidity remains high, but most of the complications may be prevented by appropriate use of the catheter.