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Biomedical subjects

A Nenciu

Publications and source records attributed to A Nenciu.

11 recordsLinked to original sources
PubMed2003

[Visual fields defects in cerebral hemorrhagic vascular accident].

Interpretation of the fields of vision forms a key part of ophthalmic and neurologic examinations. The homonymous hemianopa is a hallmark of a retrochiasmal lesion. Postchiasmal lesions that interrupt the visual pathway may have multiple causes which the circulatory disturbances is one of the most important. The authors present the case of a woman who has an isolated homonymous hemianopa produced by a vascular accident of occipital lobe, dwell upon the only manifestation of the cerebral acute hemorrhagic vascular accident was represented by an visual field defect.

Aged↗
PubMed2003

[Surgical decision in both cataract and glaucoma].

The authors try to establishes the algorithm for the treatment in patients who have both cataract and glaucoma. Clinicians must decide when to do cataract surgery, when to do glaucoma surgery and when to do a combined procedure, as well as decide which technique is appropriate. The paper presents a comparative analyze on three groups of patients who have this pathological association, regarding the factors involved in the surgery decision process and the postoperative results (visual acuity--VA, intraocular pressure--IOP, complications).

Aged↗
PubMed2002

[Ocular injuries due to allergic mechanism].

The paper presents the main ocular injuries due to allergic mechanism and it point out the actual data about etiopathogenesis of type 1 hypersensitivity and immunologic mechanism involved in allergic keratoconjunctivitis. Then are exposed the classification of ocular allergy, the main signs and symptoms, the paraclinical methods of diagnosis and the actual agents of therapy.

Anti-Inflammatory Agents↗
PubMed2002

[Secondary cataract; correlations concerning lens surgery and pseudophakia type. Therapeutic aspects].

The study presents the correlations concerning the advent of the secondary cataract depending on the surgical technique and pseudofak type (PMMA, acrylic, siliconic), as well the safety and efficacy of the YAG: Nd capsulotomy. A 3 years clinical retrospective trial was done on 320 eyes operated for senile cataract. The incidence of the secondary cataract was 11.4%, usually after 12 months, (the lower in phacoemulsification using acrylic IOL). Nd: YAG capsulotomy being done in cases with visual acuity lower than 0.6.

Acrylates↗
PubMed2002

[The role of Brinzolamide 1% ophtalmic suspension in corneal edema].

PURPOSE: The study is aimed at assessing the efficacy and safety of topical carbonic anhydrase inhibitor (IAC--i.e. ophthalmic suspension of brinzolamide 1%--Azopt) in the treatment of corneal edema. METHOD: For this purpose, we carried out an experimental, epidemiological-operational, randomised, placebo-controlled and double blind study, on three groups of laboratory animals (rabbits): group 1 (5 rabbits) included endothelial corneal injuries inflicted by ultrasound exposure by means of a phacoemulsification sound in both eyes group 2 (5 rabbits) included endothelial corneal injuries inflicted by direct trauma in both eyes group 3 (3 rabbits)--no endothelial corneal lesions (control group) In each group we instilled, all the animals, with ophthalmic suspension of brinzolamide 1% (Azopt), 1 drop t.i.d., in one eye for 14 days (starting the following day after infliction of endothelial injuries, when the corneal edema was evidenced by biomicroscopic examination) and placebo (saline solution 0.9% with the same osmolar and pH values as the Azopt) in the other eye. The assessment was performed throughout the following stages: To: preceding the infliction of corneal endothelial injuries, resorting to: biomicroscopic examination ultrasound pahimetry direct specular microscopy T1: the following day after infliction of corneal endothelial injuries, resorting to: biomicroscopic examination (the assessment of corneal edema) ultrasound pahimetry (measurement of corneal thickness and, hence edema) direct specular microscopy (cell density and endothelial ultrastructure evaluation: cellular polimegetism, pleiomorphism) T2: in the wake of 14 days therapy (after eye removal), adding to the previous examinations: indirect specular microscopy (with the same aim as the direct examination, yet examination carried out from the endothelial side) pathologic examination (using hematoxilin-eosin dye and Van-Gieson dye).

Administration, Topical↗
PubMed2002

[Posterior capsule rupture in lens surgery].

PURPOSE: The paper studies the breaks of the posterior capsule in lens surgery, specifically the incidence, causes, types, management and the methods of IOL implantation. METHODS: For this purpose, a retrospective clinical trial was performed, within: 01.06.1999-31.05.2002, on 346 eyes group operated for senile cataract (without other ocular diseases) Patients were split in two groups, based on surgical technique: group 1 with 208 eyes operated using phacoemulsification and group 2 with 138 eyes operated using extracapsular extraction technique. RESULTS: The incidence of the breaks of the posterior capsule was 8.17% for group 1 (17 eyes out of 208) and 5.07% for group 2 (7 eyes out of 138). In all cases an IOL was used, most of them being placed in the posterior chamber (in bag, in sulcus or sclera-sutured) and infrequently IOL for anterior chamber or with irian support. CONCLUSIONS: Breaks of the posterior capsule is a complication of cataract surgery, but appropriate management (viscoelastic substances, anterior vitrectomy) leads to a good outcome, with no influence on the subsequent evolution.

Cataract Extraction↗
PubMed2002

[Primary open angle glaucoma evolution after surgery].

The authors present a four year (01.02.1998-01.02.2002) clinical retrospective trial, including 209 eyes operated for Primary Open Angle Glaucoma (POAG). 52 eyes (24.8%) out of 209 eyes the progression of the disease was discovered observing the increase of the intraocular pressure (IOP), failure in achieving "IOP target" due to the insufficient filtration, the obstruction of the filtration and the deterioration of the papiloperimetrics parameters. The therapeutic approach consisted of additional medication, filtration revision, subsequent surgical treatment physical end/or classic. The authors suggest a sequence for the operated cases of POAG, but that continued to progress, postoperative IOP "seemingly normal" requiring the follow-up for t e disease, in spite of using entire methods of the treatment.

Algorithms↗
PubMed2001

[Trabeculectomy and nonpenetrating surgery in glaucoma].

The purpose of the study is to compare the efficiency of classical trabeculectomy and with the punch and nonpenetrating deep-sclerectomy in patients with primary open angle glaucoma. The studied groups comprise patients with uncontrolled intra-ocular pressure with medical therapy and/or laser. The results of the study emphasize the following conclusions: the decrease of intra-ocular pressure is comparable in classical trabeculectomy and with punch the decrease of intra-ocular pressure is comparable in classical trabeculectomy and nonpenetrating surgery. we consider the non penetrating surgery an interesting alternative to the classical trabeculectomy, with better control of intra-ocular pressure the complications of non penetrating surgery are reduced.

Glaucoma, Open-Angle↗
PubMed2001

[Non surgical alternatives in the treatment of the primitive open angle glaucoma].

Lowering of the intraocular pressure--the main risk factor in glaucoma neuropathy--is the major goal in the treatment for primary open angle glaucoma. The goal of the study is to compare the results of topical administration of the next therapeutical agents: b-blockers, prostaglandin analogs, topical carbonic anhydrase inhibitors and selectives adrenergic a-2 agonists. The studied groups emphasize the efficiency of the first line monotherapy and of the combined therapy, maintaining the quality of life, preserving the visual function, the minimal side effects and the compliance of the patients.

Antihypertensive Agents↗