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Biomedical subjects

A Neetens

Publications and source records attributed to A Neetens.

At least 109 records · Page 6Linked to original sources

Pattern and flash visual evoked responses in multiple sclerosis.

In multiple sclerosis (MS), increase of delay may be important, but the earlier change is the behavior of the wave shape; amplitude is always lower even in MS patients without visual subjective symptomatology, provided not only flash but also pattern stimulation is performed. Normal amplitude with pattern stimulation does not necessarily mean normal with flash. Combining both stimulation methods, we obtained lowering of amplitude and change of wave shape in 100% of cases while latency was increased in only 77% of cases. Sectorial ischemic neuropathy, and open angle glaucoma patients show the same findings, which emphasizes that the method is not specific for demyelinating diseases, nor selective for papillomacular bundle involvement, but that VER, considering only its first components, reflects axonal damage somewhere in the visual pathway. Flash and pattern VER might be even more pathognomonic in MS than oligoclonal gammaglobulin fractionation on agar, positive in 75% of cases. It is suggested that subclinical MS cases should be submitted to full electro-ophthalmographic investigation.

Form Perception↗

The superior oblique: a challenging extraocular muscle.

Isolated paralysis of one or both superior oblique muscles in a consecutive series of 43 patients was found to occur most often by indirect injury to the skull. The etiology in the group of spontaneous cases was mostly vascular. With rare exceptions the latter recovered spontaneously. Those with traumatic palsy may be due to "contrecoup" trauma at the decussation of the nerves or by decompensation of the cerebral fusional mechanism, with dissociation of the images of the two eyes and subsequent vertical deviation. The traumatic cases never recover spontaneously and recession or myectomy of the ipsilateral inferior oblique with or without recession of the contralateral inferior rectus is recommended but only in cases of more than 8 diopters squint, and in cases which do not adapt themselves by minor head-tilting.

Adult↗

Pattern and flash evoked responses in disseminated and selective optic pathway damage.

In multiple sclerosis (MS), an increase in delay in visual evoked responses (VER) may be important, but an earlier change is the behaviour of the wave-shape; amplitude is always lower even in MS patients without subjective visual symptoms, provided not only flash but also pattern stimulation is used. Normal amplitude with pattern stimulation does not necessarily mean normal amplitude with flash stimulation. Combining both stimulation methods, we found lowering of amplitude and change of wave-shape in 100 per cent of cases while latency was increased in only 77 per cent. Flash and pattern VER might be even more pathognomonic in MS than oligoclonal gammaglobulin fractionation on agar, which is positive in 75 per cent of cases. We recommend that subclinical cases of MS should be submitted to full electro-oculographic investigation. Patients with sectoral ischaemic neuropathy and open angle glaucoma (OAG) show the same findings; this emphasizes that the method is not specific for demyelinating diseases, nor selective for papillo-macular bundle involvement, but that VER, considering only its first components, reflects axonal damage somewhere in the visual pathway.

Evoked Potentials↗

Pseudophakalia.

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Age Factors↗

Presumed inflammatory maculopathies.

The macular disorders are classified according to the originally affected layer and the probable cause of the disease: presumed inflammatory or traumatic, iatrogenic, toxic, metabolic or trophic, and hereditary. Three young female patients are reported who had presumed inflammatory diseases: CBPE-complex (APMPPE), pigment epithelium (pigment epitheliitis), and neuroretina (acute macular neuroretinopathy). APMPPE is considered to be a choriocapillaritis closely related to a soft photocoagulate. They recommend careful follow-up of acute neuroretinopathy because through "disuse" a disease of one layer may progress to other layers as they are metabolically interdependent.

Adult↗