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Biomedical subjects

A Naylor

Publications and source records attributed to A Naylor.

At least 37 records · Page 2Linked to original sources

Professional education and training for trainers.

There is a worldwide need for health professionals knowledgeable in lactation physiology and breastfeeding management. The seven step Wellstart education program is aimed at physician-nurse teams from teaching hospitals in developing nations. In its 6 years of operation, it has taught 64 such teams, whose members have in turn taught others in their own countries. This success demonstrates the possibility for a major contribution to promoting breastfeeding.

Breast Feeding↗

At risk drinkers.

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Alcohol Drinking↗

The role of vasopressin as an antipyretic in the ventral septal area and its possible involvement in convulsive disorders.

Perfusion of the peptide, arginine vasopressin (AVP), within the ventral septal area (VSA) of the brain of a number of species reduces fever but not normal body temperature. This antipyretic response appears to be mediated by AVP receptors of the V1 subtype. Lesions of the VSA with kainic acid are associated with prolonged and enhanced fevers in rats. A role for endogenous AVP in fever suppression within the VSA comes from several types of experiments: (1) AVP release within the VSA is inversely correlated to fever height; (2) AVP antagonists or antiserum injected into the VSA prolong fever; (3) animals lacking endogenous AVP in the VSA (Brattleboro rat, long-term castrated rat) develop enhanced fevers. Electrical stimulation of the AVP-containing cell bodies of the bed nucleus of the stria terminalis (BST) orthodromically inhibits VSA neurons and also suppresses fever; the latter effect can be abolished with application of a V1 antagonist to the VSA. Iontophoretic studies indicate that AVP inhibits glutamate-stimulated activity of thermoresponsive and other VSA neurons. AVP can also act in the VSA to cause severe motor disturbances; this action is receptor mediated and increases in severity upon sequential exposure to AVP. Because sites of action of the antipyretic and convulsive action of AVP are similar, and because animals lacking brain AVP display reduced convulsive activity, it is possible that AVP, released during fever, could be involved in the genesis of convulsive activity.

Action Potentials↗

Providing professional lactation management consultation.

The probability of successful lactation and breastfeeding can be maximized by professional lactation management consultant services such as those provided by the San Diego Lactation Program. There are four distinct service components of the program: prenatal guidance; skilled immediate postpartum assistance; a telephone consultation service; and evaluation of lactation progress and problem solving in a special lactation clinic. To insure the best care for the mother-infant couple, these services must be provided by health care professionals with "hands-on" backgrounds in one of the perinatal specialties (M.D. or R.N.) as well as knowledge and skills in the specific area of lactation. Teaching hospital-based lactation programs such as the San Diego model can offer both consultant services and provide a much needed learning opportunity in lactation and breastfeeding management for such health professionals.

Breast Feeding↗

Factors in the development of the spinal stenosis syndrome.

The spinal stenosis syndrome is a potential hazard when congenital or developmental narrowing of the bony canal, particularly in its lateral recesses where it can be demonstrated by axial tomography, places the emergent nerve root and its blood supply at risk to further small compressive elements. When lumbar disc degeneration allows rotatory and lateral instability, posterolateral bulging of the annulus fibrosus into the root canal occurs when weight is taken on the ipsilateral lower limb. Symptoms of the spinal stenosis syndrome do not arise until the development of this instability. To relieve the symptoms, the nerve root must be freely mobilised and decompressed by full lateral decompression, with partial or total facetectomy if necessary, by enucleation of the intervertebral disc and by removal of the posterolateral portions of the annuli fibrosi.

Bone Diseases, Developmental↗