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Biomedical subjects

A Navarro

Publications and source records attributed to A Navarro.

At least 235 records · Page 13Linked to original sources
PubMedDate not supplied

Andalusol, a diterpenoid with anti-inflammatory activity from Siderits foetens Clemen.

The anti-inflammatory activity of andalusol (ent-13(16),14-labdadiene-6 alpha,8 alpha,18-triol), a diterpenoid obtained from the acetone extract of Sideritis foetens Clemen, has been investigated. This compound was able to inhibit acute inflammatory processes induced by carrageenan or 12-O-tetradecanoylphorbol acetate (TPA) after oral or topical administration. Quantitation of the neutrophil specific marker, myeloperoxidase (MPO), demonstrated that its topical anti-inflammatory effect was associated with reduction in neutrophil infiltration into inflamed tissues. Interaction of andalusol with leukocyte functions and histamine release from mast cells was analyzed in vitro. At a concentration of 100 microM andalusol decreased beta-glucuronidase release from calcium ionophore A23187-stimulated rat peritoneal leukocytes. However, it failed to affect superoxide generation on TPA-stimulated leukocytes and it was non toxic to leukocytes up to 100 microM (assayed in terms of lactate dehydrogenase release). Andalusol produced a dose-dependent inhibition on histamine release from rat peritoneal mast cells stimulated by compound 48/80 or calcium ionophore A23187. These results suggest that andalusol possesses an anti-inflammatory profile, and it is in part responsible for the anti-inflammatory activity attributed to this plant.

Animals↗
PubMedDate not supplied

Effects of three organophosphorus insecticides in the reproductive potential of Culex quinquefasciatus.

A Culex quinquefasciatus Say 1823 strain with resistant genes to organophosphates was tested in the laboratory to know the reproductive potential after exposure, as larvae, at the LC30 and LC70 (mg/l) of three organophosphorus insecticides: malathion, chlorpyrifos and methyl-pirimiphos. Data showed that fecundity was decreased significantly by malathion at LC30 = 0.0025 and LC70 = 0.0075, whereas fertility has a no significant decrement by chlorpyrifos and methyl-pirimiphos at the LC70 (0.000016, 0.00043). The sexual index was affected by chlorpyrifos and methyl-pirimiphos showing a greater number of adult females.

Animals↗
PubMedDate not supplied

[Neuroanatomy of the nuclear vestibular complex in the syrian hamster. Comparison with other mammals].

The vestibular complex has been studied since the fifties. The general conclusion of research on many mammals is that the vestibular complex has four main vestibular nuclei and some less constantly associated neuronal groups. The general distribution of the four main vestibular nuclei in the hamster does not differ substantially from that of other mammals: humans, many primates, cat, opossom, rabbit, chinchilla, guinea pig, etc. Of the many associated groups that have been described, we clearly identified groups < >, < >, < >, < >, and the interstitial nucleus of the vestibular nucleus of Cajal. However, the latter seems to be less developed than in other mammals. We present results and a map of serial sections of the vestibular area showing the most characteristic anatomic relations with brainstem structures, and the most relevant cytomorphometric results compared with other mammals.

Animals↗
PubMedDate not supplied

[Hematophagic activity of and environmental effect on the main malaria vector in Cuba: Anopheles albimanus].

An ecological study of Anopheles (N) albimanus in a suburban population of Camagüey province was carried out using a human bait in two trap points (indoor and outdoor). A higher quantity of females in the rainy season was observed together with a marked exophagic trend with peak activity in the early hours of the evening outdoor and in the early hours of the morning indoor. The abiotic influence on the fluctuation of the anophele population in both trap station was proved.

Animals↗
PubMedDate not supplied

[Ecologic indexes in the surveillance system of Aedes aegypti (Diptera: Culicidae) in Cuba].

The ecological indexes called diversity (H') and equitability (J') of the mosquito species were determined in six of the most common reservoirs of the urban ecosystem in the Plaza de la Revolución municipality, City of Havana. Data analysis showed that according to the values of these indexes, the most dangerous reservoirs were tyres, larvitraps and artificial reservoirs in general. Reference is also made on the use of larvitraps in the surveillance system of Aedes aegypti and the detection and stabilization of mosquitoes such as Aedes mediovittatus and Culex migripalpus in the urban ecosystem. The variety of species ranged from 2 to 7 in the studied reservoirs which showed differences in the patterns of use of the resources in the urban ecosystem.

Aedes↗
PubMedDate not supplied

[Proportional abundance of culicidae in the urban ecosystem of Havana City].

Proportional abundance of the four most common mosquito species was determined in six types of breeding places located in Plaza de la Revolución municipality, City of Havana from 1993-1996. Culex quinquifasciatus exhibited values over 0.60 except in tyres and larval traps in 1993 and 1994 whereas Aedes mediovittatus showed similar values in low tanks and artificial reservoirs in 1994 (0.43 and 0.56 respectively). It was also observed that this species prefers larval traps. Aedes aegypti and Culex migripaplpus had the lowest abundance values (0.01). These results allowed us to state that there is a sort of shared use by these species of those reservoirs where they breed and that Culex quinquefasciatus is the predominant one.

Animals↗
PubMedDate not supplied

[Entomological surveillance over Aedes (S) aegypti and other culicids in Ciudad de La Habana, Cuba 1991-1996].

The results of the entomologic surveillance carried out from 1991 to 1996 in Boyeros municipality, City of Havana within the Program for Eradication of Aedes aegypti were analyzed. Data on mosquitoes fauna collected in the municipality by various sampling methods, larval survey, human bait, capture at rest and larval traps. Culex quinquefasciatus, Aedes mediovittatus and Aedes aegypti species were the most found by the different methods. It was proved that water tanks, man-made deposits, other kinds of tanks and low tanks were the most exploited resources by mosquitoes for their breeding in this municipality whereas larval surveys were the most sensitive method for detecting species since it contributed a greater variety of species. Reference is made to the search for a mechanism that help estimate adult populations from larval indices provided by surveys and the method of capture at rest is stressed as the most sensitive method for adult mosquitoes, particularly for dengue vector within the surveillance system aimed at this species.

Aedes↗
PubMedDate not supplied

[The ecological succession of mosquito species in the town of Boyeros, Ciudad de la Habana 1994-1996].

An analysis was made on the incidence of Culicidae in Boyeros municipality, City of Havana from 1994 to 1996 based on the requirements of the national program for eradication of Aedes aegypti. A total of 13 species was detected in which Aedes mediovittatus predominated during 3 years of study, followed by Culex quinquefasciatus whereas for the first time Aedes albopictus species was found in the territory. People's Councils Wajay, Santiago de las Vegas and Armada exhibited the highest values of infestation by Culicidae in the municipality, therefore, they required that anti-Aedes program, operators paid more attention to this situation. It was found that depots preferred by Culicidae for breeding were larval traps followed by low tanks in 1994 and 1995 and by other reservoirs in 1996. A mediovittatus preferred larval traps whereas Cx. quinquefasciatus preferred low tanks except in 1996 when this species was mostly found in other tanks. 93% of all test-positive reservoirs found were colonized by only one species, whereas 7% presented larvae from 2 species or more. A. mediovittatus and C. quinquefasciatus were the most related, above all in low tanks.

Aedes↗
PubMedDate not supplied

[Evaluation of motor and sensory neuroconduction of the median nerve in patients with carpal tunnel syndrome treated with non-coherent light emitted by gallium arsenic diodes].

INTRODUCTION: The treatment selection in the carpal tunnel syndrome according to the damage of the median nerve is important and all of these have adverse effects. A good alternative without undesired reactions is irradiation of the carpal tunnel with not coherent light between 920 and 940 nm emitted by gallium arsenide diodes, resembling the physic and therapeutic laser effects. PATIENTS AND METHODS: Twenty-six female patients with idiopathic middle carpal tunnel syndrome were irradiated 15 minutes daily during three weeks. The median nerve motor and sensitive neuroconduction was studied before and immediately after the treatment. RESULTS: The abnormal neuroconduction variables (latency, amplitude and velocity conduction) did not modify when treatment concluded, in spite of all the patients reported disappearance of pain and numbness in damaged hands. CONCLUSIONS: Not coherent light does not change the fibers functional state explored by conventional neuroconductions techniques. It remains to know if this light produces fine fibers improvement.

Arsenicals↗
PubMedDate not supplied

[Biologic effect of diflubenzuron on Blattella germanica (Dictyoptera: Blattellidae)].

The Amejeiras strain of Blatella germanica (Dictyoptera: Blattellidae) kept in lab conditions since 1994 and susceptible to arpocarb, malathion and cipermethrin insecticides, was studied. This strain was treated with 4 diflubenzuron (Dimilin OMS 1804) concentrations supplied by feeding nymphs at their first stage of development, with the purpose of determining their effect on the survival, phenotype and period of nynmphal development of this species. The dosage-mortality line of regression was determined and the values of CE50 = 0.042% and CE95 = 0.357% were obtained. Sublethal effects were observed in the nymphs treated with the 4 tested concentrations whereas the morphogenetic effects in adult insects only occurred when they were exposed to higher concentrations (0.25% and 0.4%). The nymph development stage showed a highly significant increase when the diflubenzuron concentration was raised. (F = 11.64; p < 0.001).

Animals↗
PubMedDate not supplied

[Episodic ++paroxysmal hemicrania or chronic paroxysmal hemicrania in pre-chronic state?].

Two women suffered from strictly unilateral, periocular headaches for many years. The clinical characteristics of headaches were those described in chronic paroxysmal hemicrania. However, both patients showed an episodic evolution of pain. In one case, this stage could be considered pre-chronic because it was later followed by the classic and apparently definitive chronic period of the disorder. In the second case the episodic stage persisted all along the evolution of the disease and the headache did not reach the chronic period. The patient has been free of pain without treatment for the last three years. This second observation can be considered as an example of episodic paroxysmal hemicrania. In the episodic cases the response of pain to indomethacin can be difficult to be ascertained.

Adult↗