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Biomedical subjects

A Natale

Publications and source records attributed to A Natale.

At least 127 records · Page 7Linked to original sources
PubMed1990

[A case of primary lymphoma of the rectum].

The Authors describe a case of primary rectal lymphoma. The primitive involvement of this area is infrequent. The Authors emphasize the difficulty of preoperative diagnosis. The therapeutic approach should allow for correct staging which is only obtained by means of diagnostic studies aimed at excluding multicentric localisation. Sensitivity to radiotherapy has led the Authors to propose it as primary treatment, at least in stage I; surgery must be considered elective in stage II or in cases of need. Chemotherapy is indicated alone or in association with radiotherapy or surgery.

Aged↗
PubMed1989

Rhythm of carnitine levels in serum and urine of normal subjects.

A study of the diurnal serum and urine levels of L-carnitine and acetylcarnitine was carried out in eleven healthy volunteers. No significant difference was found between the levels in the morning and in the afternoon, although a higher carnitinaemia was shown in the waking hours when the energy demands were higher.

Acetylcarnitine↗
PubMed1988

Monocyte and polymorphonuclear leukocyte toxic oxygen metabolite production in multiple sclerosis.

Lipid-laden macrophages, which are predominantly derived from blood monocytes, are present at sites of active multiple sclerosis demyelination and are assumed to be involved in the demyelinating process. These inflammatory cells produce a variety of toxic oxygen metabolites which can mediate host tissue destruction. We measured production of two oxygen metabolites by monocytes and polymorphonuclear leukocytes in MS patients and controls. Stimulated monocytes produced significantly more hydrogen peroxide, superoxide, and chemiluminescence in the MS group than controls. The polymorphonuclear leukocyte, an inflammatory cell that appears to contribute little to MS demyelination, did not demonstrate increased production of toxic oxygen metabolites in the MS patients as compared to controls. These results suggest that blood monocytes in MS patients are primed to produce increased amounts of cytotoxic oxygen metabolites when exposed to inflammatory stimuli.

Humans↗
PubMed1986

Effects of dietary fish oil supplementation on polymorphonuclear leukocyte inflammatory potential.

Polymorphonuclear leukocytes (PMNLs) are an important contributor to inflammation and are thus a part of the pathophysiology of many human diseases. We assessed the effect of fish oil on PMNL inflammatory potential by measuring chemiluminescence and superoxide production before and after six weeks of daily cod liver oil ingestion by healthy volunteers. Phagocytosing PMNLs demonstrated a 27% decrease in chemiluminescence (P less than 0.05) and a 64% decrease in superoxide production (P less than 0.01), following the cod liver oil supplementation. Analysis of PMNL and platelet fatty acids revealed the appearance of eicosapentaenoic acid and a significant decrease in arachidonic acid in both types of cells.

Dietary Fats↗
PubMed1981

[R wave variations during the bicycle exercise test].

R-wave changes have been measured in 90 normal subjects during exercise testing on the bicycle. We have found a 22,2% R-wave mean decrease in all the subjects independently from their age. This results, in our opinion, may be due to the heart volume decrease during dynamic exercise in normal subjects. In according to the Brody effect, heart volume reduction decrease radially orientated cardiac vectors and therefore QRS amplitude is reduced.

Adult↗
PubMed1981

[Effect of isometric force (handgrip) on R wave amplitude].

We have measured R-wave amplitude during isometric stress-handgrip test in 30 normal subjects, without finding any significative variation. We believe, in according to our angiographic and echocardiographic experience, that such a behaviour is due to the absence of heart volume modification during handgrip test.

Adult↗
PubMed1980

[Complications of surgery of the rectum].

The immediate and late postoperative complications of surgery for rectal neoplasia have been examined. Both general complications and those arising out of specific techniques are discussed. The personal series involves 110 cases of rectal cancer operated at the Siena Cepartment of Surgical Pathology.

Humans↗
PubMedDate not supplied

[Perineal hernia].

The authors base this study on a case of perineal hernia referred to their attention. In the light of the scant international literature on this subject, they focus on the topographical anatomy of the pelvic floor in order to gain a clearer understanding of this pathology, as well as their classification into median, lateral, anterior and posterior forms. Above all, the authors draw attention to the importance of the differential diagnosis of perineal hernia from Bartholin cysts or vulvar tumours in relation to anterior perineal hernia, and perianal abscesses in relation to posterior hernia. They underline the value of ultrasonography or TAC during the diagnostic procedure. Lastly, they examine the channels of aggression for this type of hernia which may be abdominal, perianal or combined (abdominal and peri-anal), as well as the repair techniques used, varying from direct suture with non-absorbable material to the use of prolene mesh or flaps if the hernia breech is very large.

Hernia↗
PubMedDate not supplied

Foreign body aspiration. An atypical clinical case.

The case of a 3-year-old female with an atypical presentation of foreign body aspiration is described. Resistance to the therapy, mild radiological signs and a high index of suspicion of the clinician could lead to the right diagnosis.

Bronchi↗
PubMedDate not supplied

Systemic anaphylaxis induced by physical exertion: a case report.

Anaphylaxis is a systemic reaction which can be very dangerous in many patients. In addition to the most common antigens (drugs, venoms, foods), physical exercise can provoke anaphylaxis in the sensitized patients. The mechanism of this reaction is still unknown. In this report, we describe a case of exercise-induced anaphylaxis in a 25 year old female who had experienced two syncopal attacks during strong physical activity. On other occasions she had noticed that prolonged work would cause urticaria, pruritus and numbness. During hospitalization, on two occasions a treadmill stress test induced bronchial spasm, urticaria and hypotension. We believe that the association of urticaria and anaphylaxis would suggest the possible presence of a vasoactive substance released from the mast-cells and basophil leucocytes.

Adult↗