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Biomedical subjects

A Narang

Publications and source records attributed to A Narang.

At least 145 records · Page 8Linked to original sources
PubMed1987

Acute renal failure amongst children in a tropical environment.

The pathogenetic factors leading to acute renal failure (ARF) in 223 children between the ages of 20 days and 14 years were studied. Diarrhoeal diseases were responsible for ARF in 49.8%, acute glomerulonephritis in 34.1%, drug induced intravascular hemolysis in glucose -6-phosphate dehydrogenase deficiency in 4.5%, snake bite in 4%, hemolytic uremic syndrome in 2.2%, and miscellaneous causes in 5.4%. Dialysis was instituted in 178 children and the others were treated conservatively. Renal histology in 39 out of 76 children who presented with an acute nephritic illness revealed acute endocapillary proliferative glomerulonephritis in 27 and crescentic glomerulonephritis in 12. The histology in 79 out of 147 remaining patients showed acute tubular necrosis in 64, acute cortical necrosis in 13, and acute interstitial nephritis in 2. Overall mortality was 27.4%. This high incidence of ARF due to infective diarrhoeas and dysentery reflects poor socio-economic and hygienic conditions, inadequate facilities in rural areas, delays in seeking medical advice, and lack of knowledge about fluid and electrolyte therapy amongst the staff.

Acute Disease↗
PubMed1985

Lack of association between barotrauma and air leak in hyaline membrane disease.

A retrospective analysis of 632 infants with hyaline membrane disease admitted to this regional intensive care nursery between 1 July 1974 and 31 December 1982 showed that 387 (61%) received mechanical ventilation. The ventilator pressures at the time the first air leak was detected were available from the records of 120 of 154 (78%) of the infants who sustained pulmonary air leak. There was a significant downward trend in both peak and end expiratory pressure used during the study period. The downward trend in peak pressure persisted when inborn and outborn infants, boys and girls, and infants more than 27, and 23 to 27 weeks' gestation were examined separately. Despite these trends there was no reduction in the incidence of pulmonary air leak in any group. These data do not support the hypothesis, implicit in the term barotrauma, that a reduction in ventilator pressures decreases the risk of air leak.

Barotrauma↗