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Biomedical subjects

A Nanda

Publications and source records attributed to A Nanda.

115 records · Page 7Linked to original sources

A prospective survey of pediatric dermatology clinic patients in Kuwait: an analysis of 10,000 cases.

Skin diseases are common in children. However, only a very few prospective epidemiologic surveys are available in the literature. The present survey was directed at determining the spectrum and pattern of skin diseases of children in Kuwait. A total of 10,000 consecutive new patients were studied; 96% were children of Arab descent. A female preponderance (52%) was observed, and infants constituted the largest group within the patient population (28.7%). A total of 162 dermatoses were recorded. Atopic dermatitis was the most prevalent dermatosis (31.3%), followed by viral warts (13.1%), alopecia areata (6.7%), pityriasis alba (5.25%), psoriasis (4%), and diaper dermatitis (4%). Atopic dermatitis was the most frequently seen dermatosis in children of all age groups, whereas, viral warts were more prevalent in school-age children. The prevalence of alopecia areata and psoriasis was higher than reported earlier in other ethnic groups. A female preponderance was seen in children with alopecia areata, psoriasis, vitiligo, acne vulgaris, contact dermatitis, and pityriasis rosea. Dermatitis, superficial cutaneous infections, and nevi/nevoid disorders were the important groups studied.

Age Distribution↗

Childhood lichen planus: a report of 23 cases.

Lichen planus (LP) in children is a rare entity. We report 23 cases of childhood LP seen over a period of 7 years. Ninety-six percent of the children were of Arab ancestry. There were 52% boys and 48% girls. Classic LP was the most common clinical variant (70%), followed by eruptive generalized LP (13%). A majority of the patients had mild, localized disease. Oral involvement was seen in 39% of patients. Topical steroids were the mainstay of treatment in most of the cases. Children with chronic and recurrent disease responded to dapsone therapy, whereas in those with eruptive and widespread disease, UVB phototherapy was found to be safe and effective. The present report highlights the salient clinical features, treatment, and course of LP in children in Kuwait compared to those reported in children of other countries as well as those of adults.

Administration, Topical↗

Lipoid proteinosis: report of four siblings and brief review of the literature.

Lipoid proteinosis (Urbach-Wiethe disease) is a rare autosomal recessive disorder associated with deposition of periodic acid-Schiff (PAS)-positive hyaline material in various tissues including skin, mucous membranes, and internal organs. A family is reported in which four siblings (two boys and two girls) born to nonconsanguineous parents had lipoid proteinosis. All had the characteristic hoarseness of voice and three had skin lesions. The diagnosis was confirmed by the presence of typical features on light and electron microscopy.

Child↗

Prostaglandin F2 alpha in leprosy--a preliminary study.

Prostaglandin F2 alpha was estimated in the sera of fifty patients in the leprosy spectrum to find out the status of prostaglandins in response to Mycobacterium leprae. Contrary to expectation, PGF2 alpha could be detected in only twenty-eight percent of leprosy patients. This preliminary finding is discussed in detail in the paper.

Dinoprost↗

Treatment in patients with glioblastoma multiforme and poor performance status: is it worthwhile?

It has not been ascertained that treatment of glioblastoma multiforme of the brain (GMB) favorably alters the prognosis in patients with poor pretreatment performance status (PPS). We report on 52 patients with GMB and PPS. The mean survival of 43 treated persons was 19 +/- 12 months (95% confidence interval) and of nine untreated individuals, 2 +/- 1 months (p > 0.50); the corresponding survival rates at 1 year were 39 +/- 16% and 0% (p > 0.05) and at 2 years, 15 +/- 12% and 0% (p > 0.40). We recommend active treatment of patients with GMB even when they present with poor functional status.

Aged↗