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Biomedical subjects

A Nagy

Publications and source records attributed to A Nagy.

405 records · Page 23Linked to original sources
PubMedDate not supplied

[Study of the ocular toxicity of ethambutol].

Thirty cases were studied, of children aged between 4 and 5 years, with latent or manifest (overt) pulmonary tuberculosis under treatment with etambutol (EMB) administered intermittently (2/7) in amounts of 25 mg. per kg of body weight. Ophtalmological investigations consisted in evaluation of the visual acuity, of the visual field, of the chromatic sense, pupillary reflexes and an examination of the fundus. These were performed before the start of the treatment, then at 3 and 6 months after the treatment was begun. No cases of toxic ocular manifestations was recorded. The results are discussed on the basis of data from the literature, and care is recommended in the administration of etambutol.

Adolescent↗
PubMedDate not supplied

Effect of dimethylnitrosamine on the concentration of polyamines in rat liver and kidney.

Newborn female rats were injected once with dimethylnitrosamine. The polyamine content of the liver and kidneys was measured and compared to the respective controls. Both liver and kidney polyamine concentrations were found to decrease in both organs up to one month of age. The polyamine concentrations then increased in the carcinogen treated animals, whereas the control levels remained unchanged. The concentration of polyamines was greater in the left kidney than in the right one. A close correlation was found between the concentration of polyamines and histological findings during tumour development.

Adenocarcinoma↗