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Biomedical subjects

A N Mitrofanov

Publications and source records attributed to A N Mitrofanov.

11 recordsLinked to original sources

[The effect of tocopherol and nicotinic acid on the microcirculation and blood coagulability in patients with ischemic heart disease].

Patients with ischemic heart disease were treated by routine techniques (53), using also tocopherol acetate (54) and combination of tocopherol with nicotinic acid (53). Changes of the microcirculatory bed of the bulbar conjunctiva was studied biomicroscopically and in the process of blood coagulation hemoelectrocoagulographically. Complex treatment using tocopherol acetate produced a positive effect on the coagulation properties of the blood and did essentially influence the fibrinolytic activity and microcirculation. Tocopherol plus nicotinic acid resulted in normalization of the blood coagulation process, favoured activation of fibrinolysis and improvement of the microcirculatory bed.

Adult↗

[A case of Gierke's disease].

A rare clinical case is reported of a patient presenting with glucose-6-phosphatase deficiency (Gierke's disease). Shown in the advanced stage of the disease is the polyorgan involvement. The report contains a brief review of relevant medical literature concerning etiology, pathogenesis, clinical picture, diagnosis of von Gierke's disease.

Adult↗

[Recurrent thromboembolism of the pulmonary artery in a female patient with a gallbladder tumor].

A clinical case is submitted of development in a female patient of recurring thromboembolism of small branches of the pulmonary arteries preceding the clinical manifestations of a disease. Subsequently the above female patient was diagnosed as having developed carcinoma of gallbladder. An item of information is given concerning the syndrome of hypercoagulation and development of thromboembolism in malignant tumors.

Blood Coagulation Disorders↗

[The late results of electrical cardioversion in patients with a chronic form of atrial fibrillation].

The paper presents results of study of the electric cardioversion (ECV) long-term effects in 216 patients with a chronic form of cardiac fibrillation (CF). The CF relapses were found to occur in 45.4% of cases, with the 43.9% of the whole number of the above relapses falling on the first two weeks, during six months after successful ECV. CF relapses were significantly more common in patients with rheumatic and ischemic heart diseases, as well as in those persons with CF duration of more than one year and in recurrent arrhythmias in instances of left ventricle sizes exceeding 45 mm. CF form does not appear to have a demonstrable effect on the ECV long-term results.

Adolescent↗

[Left ventricular hypertrophy in patients with nephrogenic arterial hypertension].

Incidence and geometric peculiarities of hypertrophy of the left ventricle of the heart (HLVH) were studied on the basis of findings from the echocardiographic investigation done in 86 patients with chronic glomerulonephritis (ChGN) with arterial hypertension (AH), with the renal function being preserved and at the early stages of renal insufficiency. HLVH was detected in 30.2% of the patients, in 80.8% of whom it was concentric, and in 19.2% eccentric, in 76%--symmetric and in 23.1%--asymmetric. Incidence of HLVH did not correlate with sex, clinical variant of ChGN, renal function status, and increased with the degree and duration of AH. There was no difference in geometric peculiarities between sexes, clinical variants of ChGN, and no association with degree and duration of AH as well as with functional state of the kidneys.

Adult↗