[Current trends in the development of medical laboratory equipment (a review of the displays at the Public Health-80 Exhibition)].
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Biomedical subjects
Publications and source records attributed to A N Kuznetsov.
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Effect of constant magnetic field with the induction of 23 mT (non-homogeneity in the object region not higher than 0.5 mT) on the frequency of spontaneous impulse activity, resting potential and input resistance of neurons was studied. Results of studies of 7 silent and 16 spontaneously active neurons were presented as statistically processed data on silent giant neurons of the right pleural ganglion and giant spontaneously active neuron N5 of the right parietal ganglion. A reliable decrease of the frequency of spontaneous impulse activity and an increase of membrane resistance of spontaneously active neuron at magnetic field superposition were shown.
The functional interpretation is delivered of the principal morphological subdivisions of the paired limbs in the vertebrate animals, that is of the girdles and free parts. To distinguish between those, the functional criteria are suggested. On this basis the variants are considered of suspension of the fore and hind limbs in various groups of Gnathostomata. In the hind limbs the boundary between the girdle and the free part does always pass through the hip joint. In the fore limb the corresponding boundary passes through the shoulder joint in fishes. However, in most tetrapods it shifts proximally due to the release of the scapulocoracoid mobility. This tendency reached its maximum in turtles and viviparous mammals. The main attention is paid to the analysis of the arrangement of the scapulocoracoid suspension in various groups of tetrapods.
Copper (II) ions were used as paramagnetic labels to study the role of functional groups of structural proteins (SP) of xenobioprosthetic valves in the process of transition metal ions coordination as well as for investigation of changes in complexing properties of these proteins under influence of the recipient media. The dependence of Cu(II) coordination sphere composition in complexes with SP on the pH-value has been determined. Research of influence of the valves' calcification process on the coordination properties of the SP are in progress.
Some physico-chemical properties of lecithin lyposomes and the effects of pH, temperature and ionic strength changes are studied by ESR using hydrophobic and hydrophylic nitroxyl radicals as spin probes. The structure differences between outer and inner layers of bilayer liposomes are observed using auxiliary water soluble paramagnetic complex and attributed tentatively to the different curvature signs of both layers. Lower estimates of transversal diffusion rates of both probes throught the membrane are obtained using exchange broadening technique and water soluble reducing agent. The limiting step in this diffusion is revealed, caused by the transport of a charged group of the diffusing molecule through the hydrophobic membrane space.
The average morbidity level in scarlet fever for the period of 1972-1990 in Moscow was 230.9 cases per 100,000 of the population and the annual economic damage was 2-2.5 million rubles. The highest morbidity rate values were registered among children attending children's institutions, and in this group among children aged 3-6 years. Cohort and disperse analysis revealed that age-dependent fluctuations of morbidity rate had a regular character and significantly differed. An increase in scarlet fever morbidity was registered simultaneously with elevated levels of morbidity in tonsillitis and acute respiratory diseases and occurred several weeks after a rise in tonsillitis morbidity. Contamination with group A streptococci was higher among "organized" children of preschool age than among other groups of the population. T serovars 4/28, 8/29/Imp.19, 3/13/B3254 and 1, constituting 44% of all isolated Streptococcus pyogenes strains, and OF type 2 (44%) and 22 (20%) occurred most frequently. Among the strains isolated from patients T-4 and OF-2 types prevailed.
To carry on correct investigation of variable magnetic field influence on biological objects the method of complex usage of Helmholtz's rings is suggested. For this purpose the same Helmholtz's rings are suggested to be used to produce false radiation in the control experiments with opposite in phase current in the coils of the Rings. Calculations of the homogenuity of the magnetic field are made with nomograms drawn. With the aid of the nomograms one can choose parameters of the rings, which ensure any presettled degree of screening of initial operational magnetic field.