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Biomedical subjects

A N Kosiakov

Publications and source records attributed to A N Kosiakov.

13 recordsLinked to original sources
PubMed2003

[The influence of contrykal on intraoperative blood loss during endoprosthesis implantation of the hip joint].

Application of the proteases inhibitors constitutes one of possible pharmacologic methods of the blood loss compensation during performance of operative intervention in orthopedics, especially for endoprosthesis of the main joints. Application of contrykalum for endoprosthesis of the hip joint is expedient, if prognosticated intraoperative blood loss exceeds 1000 ml. Efficacy of preparation was not established for the lesser blood loss cases.

Arthroplasty, Replacement, Hip↗
PubMed2003

[Preoperative patient blood preservation as an alternative to donor blood transfusion during joint endoprosthesis surgery].

In 79 patients, to whom total endoprosthesis of the knee and hip joints were performed, the efficacy of preoperative blood preparation was studied up. The method is effective and secure alternative to the donor blood transfusion in orthopedic surgery. Taking into account the ability of patient with rheumathoid arthritis to restore the hemoglobin level, the expediency of preoperative blood preparation in them must be determined individually.

Arthroplasty, Replacement↗
PubMed2003

[Impact of anesthesia methods on the course of perioperative period in endoprosthesis of the hip joint].

The impact of methods of anesthesia on the course of perioperative period was studied up in 132 patients, to whom the total endoprosthetics of the hip joint was performed. The occupation in the operation room term and analysis of the postoperative pain syndrome occurrence with its cupping served as comparative categories for general and regional methods of anesthesia. Central neuronal blockade, epidural and spinal anesthesia have predominant significance for enhancing of the intraoperative and postoperative analgetic defense.

Anesthesia↗
PubMed2000

[Analysis of complications of operation for appendicular peritonitis in children].

Complications, occurred after the operation for appendicular peritonitis in children, were analyzed. The frequency of the complications occurrence in patients with an acute catarrhal appendicitis had constituted 1.4%, with phlegmonous one--3.5%, gangrenous--12.1%, gangrenous appendicitis with local restricted peritonitis--18.9%, with diffuse purulent peritonitis--42%. The dependence of the complications frequency on character and severity of primary changes in abdominal cavity was established.

Adolescent↗
PubMed1998

The role of purinergic and adrenergic transmitters of the sympathetic system in the control of arterial blood pressure variability.

Variability of mean arterial pressure (MAP) was examined in chronically instrumented, conscious, freely moving rats with pharmacologically altered efferent sympathetic influences on the cardiovascular system. MAP was recorded for 30 min beat-to-beat, using a computer under both control and experimental conditions: after administration of adrenoceptor antagonists (prazosin or phentolamine) or under P2X receptor inactivation produced either by desensitization with alpha, beta-methylene ATP or by PPADS blockade. Inhibition of adrenergic sympathetic effects on the cardiovascular system produced long-lasting and stable decrease in MAP. Prazosin did not modify MAP variability whereas phentolamine enhanced it. Under P2X receptor desensitization MAP decreased, the hypotensive effect being accompanied by a significant increase in MAP variability. A similar increase in MAP variability was observed after PPADS administration, while MAP level was not changed. Administration of PPADS in combination with phentolamine increased MAP variability more significantly than each of the drugs given separately. Changes in MAP variability under the various experimental conditions were not consistently correlated with changes in heart rate variability. We propose that ATP, being a mediator of sympathetic vasoconstriction, participates in baroreceptor-induced stabilization of MAP level.

Adenosine Triphosphate↗
PubMed1990

[Rational methods of cutaneous plastic surgery using local tissues in open injuries of the hand].

Based on the experience with treating 214 patients, the authors distinguished the most frequent types of traumas to the hand, or fingers, which required the performance of the cutaneoplastic operations, and systematized the variants of such operations with the use of local cutaneous flaps. The primary cutaneous plasty, and as well the complex postoperative treatment of the patients with open injuries to the hand permitted to reduce the incidence of postoperative complications from 46 down to 15%, shorten the duration of treatment by 1-2 weeks.

Hand Injuries↗
PubMedDate not supplied

[Hemodynamic features of operations with tourniquet in orthopedic surgery].

The investigation was carried out in group of 38 patients where total arthroplasty knee joints operations were planned and performed. The operations have been performed under general or regional anesthesia. Usage of a knee joints arthroplasty technique under a compression with tourniquet in conditions of a general anaesthesia, is accompanied by a hypertensive syndrome requiring for a hemodynamic correction. The decompression after prosthetic repair is integrated to a recirculation hypotension especially expressed with usage of hypotensive drugs. The obtained data prove the regional methods of an anaesthesia as more reasonable for total arthroplasty of knee joints.

Anesthesia, General↗