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Biomedical subjects

A N Korostelev

Publications and source records attributed to A N Korostelev.

10 recordsLinked to original sources
PubMed2005

Endovascular grafting of thoracic aortic pseudoaneurysm after operation for coarctation.

Presented herein is a case of successful repair of thoracic aortic aneurysm by endograft in a female patient 21 years after replacement of the descending aorta for coarctation. During scheduled examination the patient was found to have aneurysm of proximal anastomosis. Additional examination was followed by the stenting of the thoracic aorta using endograft manufactured by the "GORE" Company (USA). The immediate results were classified as good: aneurysm was not opacified, the patency of the vessels of the aortic arch was well preserved. According to the data of check examination carried out 5 months after operation, no graft dislocation was marked, aneurysm was not detectable. The given case demonstrates low-invasive endovascular intervention permitting the avoidance of complicated and traumatic open regrafting of the aorta and attainment of beneficial short- and long-term treatment results.

Adult↗
PubMed2003

[Dislocation of the closing element of the disk mechanical graft at aortic valve replacement].

Presented herein is the first case of dislocation of the closing element of the artificial low-profile aortic valve to the abdominal aorta, which happened during replacement. Toward completion of extracorporeal circulation a 37-year-old man showed the signs of aortic insufficiency because of dislocation of the closing element. After resumption of extracorporeal circulation repeated replacement was accomplished. To detect the site of graft cusp embolism, transesophageal echocardiography and duplex scanning of the abdominal aorta were employed. On the 18th day following the first intervention the patient developed thromboembolism to the distal arterial bed. Emergency thrombectomy from the arteries of the right lower extremity was performed and a foreign body was removed from the abdominal aorta, using left-sided thoracophrenolumbotomy. The patient was discharged from the clinic in a satisfactory condition.

Adult↗
PubMed2003

[Long-term outcomes of balloon angioplasty for aortic coarctation].

From 1994 to 2001 balloon angioplasty was fulfilled for 19 patients aged from 4 to 28 (mean 11.0+/-7.0) with discrete type aortic coarctation. Early outcomes were satisfactory in all cases. Catheterization showed 10 mm Hg decrease in systolic pressure gradient (SPG). Long-term results (from 6 months to 8 years, mean 3.0+/-2.5) were evaluated with transthoracic EchoCG, Doppler ultrasound, duplex scanning of iliofemoral segment and CT-angiography with 3D reconstruction. Surgical outcomes were considered good when SPG did not exceed 20 mm Hg for Doppler ultrasound and 25 mm Hg for Doppler EchoCG. In the study group there was statistically significant decrease in arterial pressure in right upper limb and SPG (measured with both Doppler EchoCG and Doppler ultrasonography) and rise of ankle-brachial index. Beneficial hemodynamic effect was detected in 15 from 19 patients (79%). Recoarctation has developed in 4 (21%) patients, in 1 (5.3%) case it was combined with true posttraumatic aortic aneurysm. Three patients underwent open surgical intervention with uneventful postoperative period. Aneurysmal dilatation of thoracic aorta has developed in 1 patient (5.3%), non-progressive intimal dissection - in another one (5.3%), 2 patients (10.5%) experienced ipsilateral 40-60% stenosis of right external iliac and femoral arteries. Thus good long-term outcomes of balloon angioplasty in patients with discrete type aortic coarctation were achieved in 79% cases. Patients after balloon angioplasty must be assessed regularly with non-invasive diagnostic methods such as Doppler ultrasonography, Doppler EchoCG, CT-angiography.

Adolescent↗
PubMed2002

[Roentgeno-endovascular occlusion and surgical correction of patent ductus arteriosus].

To establish the indications to classical surgical correction and roentgenoendovascular occlusion (REO) of patent ductus arteriosus (PDA) results of treatment of patients with PDA were compared. Immediate results of treatment of 209 patients with PDA were analyzed. 110 patients underwent classical surgical operations which were performed successfully in 109 (99%) patients. Complications in early postoperative period were the following: incomplete expanding of the left lung in 1 (0.9%) patient, reactive exudation into left pleural cavity--in 1 (0.9%), and chylothorax--in 1 (0.9%). REO of PDA was performed in 99 patients. Gianturco coils (COOK, Denmark) and Saveliev--Prokubovsky occluders were used. REO was successful in 93 (93.9%) patients. It failed in 6 (6%) cases including 3 cases with coils and 3--with Saveliev--Prokubovsky occluders. According to the results, PDA with diameter less than 4 mm in the narrowest part can be closed by REO with Gianturco coils. In PDA with diameter 4-10 mm Saveliev--Prokubovsky occluders are recommended. In case of PDA with diameter more than 10 mm, aortopulmonary defect or septic botallitis it is necessary to perform thoracotomy and surgical correction.

Balloon Occlusion↗
PubMed2001

Recanalization and thrombectomy of internal anastomosis in a patient with tetralogy of Fallot using the AngioJet rheolytic catheter.

The modified Blalock-Taussig shunt is the palliative treatment of choice for tetralogy of Fallot. Shunt thrombosis is a potential complication, requiring high-risk reoperation. The use of percutaneous rheolytic devices for thrombus removal in such occluded shunts has not been previously reported. We describe a case in which use of a rheolytic catheter resulted in significant thrombus removal and rapid reversal of cyanosis and dyspnea in a 5-year-old patient. The patient remains free of symptoms at 30-day follow-up.

Anastomosis, Surgical↗
PubMed2000

[Opportunity of operative traumatism decrease in patients with complicated tricuspid valve defect].

This study examined the results of surgical trivalve of 44 patients with trivalve heart defect. In all the patients the heart defect was combined with two and more complicating factors: advanced III-degree calcinosis of the valves, cardiomegaly, cardiac fibrillation, left atrium thrombosis, high pulmonary hypertension. In 20 patients the operative intervention on the heart was repeated. The analysis of the results allowed to recommend some surgical techniques which allowed to decrease surgical traumatism in patients with complicated trivalve heart defect. Low traumatism was possible because of incomplete removal of the calcium masses extending on the fibrotic ring and outside, use of two-row counter U-suture on linings for the prosthesis fixing, transdoubleatrial approach without isolation of the heart from the adhesions in dense pericardial obliteration, correction even insignificant trivalve heart defect or relative valve incompetence.

Adult↗
PubMed1991

[Catheter-balloon valvuloplasty in mitral valve stenosis (selection of the method of procedure, immediate results and the criteria of patient selection].

Catheter-balloon valvuloplasty (CBV) was carried out in 80 patients with rheumatic mitral stenosis, whose ages ranged from 22 to 68 years. Seventeen of these patients were operated on for mitral valve restenosis; I-II degree calcinosis of the mitral valve was revealed in 18 patients; seven women underwent surgery in the 24th-32nd week of pregnancy. After applying various methods (19 cases) the authors used in the last series of operations (61 cases) the Silin-Sukhov method using an original dilatation catheter with a balloon measuring in diameter up to 34 mm, which allowed pressure of up to 8 atm. to be produced during a working cycle no longer than 8 sec. As the result of CBV, the area of the mitral orifice was enlarged by no less than twice in all patients, the pressure gradient through the mitral valve and systolic pressure in the pulmonary artery reduced. The total number of complications which called for operative treatment was 3.75%. CBV is a still developing method, but already today it may be considered the method of choice in the treatment of uncomplicated forms of mitral stenosis, in I-II degree calcinosis, and when the risk of the traditional surgical intervention on the heart is increased.

Adult↗
PubMedDate not supplied

[Metabolic effects of mexidole during cardiosurgical operations using extracorporeal circulation].

The effect of mexidole on the levels of glutathione, the activity of its metabolic enzymes, glutathione reductase (GR) and glutathione peroxidase (GP), and antioxidative enzymes, superoxide dismutase (SOD) and catalase (CAT) in the red blood cells under hypothermic perfusion was studied. A total of 96 patients were examined. The study was performed before perfusion, at the cooling and warming stages, an hour after perfusion, and in the morning of a following day. Mexidole was administered to 26 patients in the evening, before surgery, and at the cooling and warming stages (Group 1). The agent was not given to 70 patients (Group 2). In Group 2, there was an association of the level of glutathione and the activity of the enzymes under study with temperature. There were the least changes observed at 30-34 and 26-29 degrees C and a substantial decrease (by more than 30%) at the cooling stage as compared with pre-perfusion values. In the mexidole group, the content of glutathione increased under all temperature conditions at the study stages (by 30 to 58%) and the activity of all the test enzymes: GR and GP up to 33%, SOD up to 20-60%, CAT by 20-30%. The elevated level of all the parameters was also preserved on the following postoperative day. It may be suggested that mexidole activates the biosynthesis of glutathione and antioxidative enzymes, thus enhancing the antioxidative defense of cell membranes.

Antioxidants↗