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Biomedical subjects

A N Ivanov

Publications and source records attributed to A N Ivanov.

At least 19 recordsLinked to original sources
PubMed2006

[Clinicohemadynamic and biochemical the effect of patients with coronary heart disease use combinated lactoovovegetarian diets and simvastatin].

This work is aimed at studying the effect of a lactoovovegetarian antiatherogenic well-balanced diet, combined with the hypolipidemic drug simvastatin, on clinicohemodynamic and biochemical parameters of patients with coronary heart disease and pronounced hypercholesterolemia (TC > 7.8 mmol/l). 43 patients suffering from coronary heart disease, stenocardia under loading (functional classes II-IV) were observed. The patients of the first group (n=17) were had an antiatherogenic vegetarian diet, the patients of the second group (n=26) had the antiatherogenic mixed diet IOC. Besides a standard antianginal therapy all the patients received simvastatin in a daily doze of 20 mg. By the end of the treat ment positive changes in clinicogemodynamic and biochemical parameters were methobolism lipid observed in both the groups of patients. The comparison of lipid parameters revealed a significant and reliable decrease in the first group.

Adult↗
PubMed2005

[The treatment of coronary heart disease by beta-adrenoblockers or tiazide diuretics preparation in combination with vegetarian diet].

Work make on 84 patients with coronare heart diseases were divided into two groups, equal quantity. The first groups were given athenolol (50 mg daily), the second--hypotiazide (25 mg daily). In every groupspart patients received an antiatherogenic lactoovovegetetarian diet, part--an standard antiatherogenic diet 10c. Time observation--24 daily. By the end of the treatment period with athenolol in backoground the vegetarian diet the level of total cholesterol decreased by 16%, low-density lipoproteins cholesterol decreased by 18%. In groups patients received an standard antiatherogenic diet these parameters practically did'nt change. In the vegetarian group the atherogenic coefficient (KA) decreased by 31%., while in the patients on standard antiatherogenic diet KA showed only a tendency for decreasing. By the end to the treatment period with hypotiazide the slight decrease in total cholesterol, KA levels and a slight increase in HDL cholesterol were observed only the vegetarian group.

Adrenergic beta-Antagonists↗
PubMed2005

[Effect of SWF-radiation on thrombocytes and erythrocyte functions of albino rats upon stress condition].

With the help of a specially designed generator, we have investigated the effect of electromagnetic SWF-oscillation, at nitric oxide molecular spectrum of radiation and absorption, on the function of thrombocytes and erythrocytes of albino rats in the state of immobilizing stress. 5, 15 and 30 min long SWF-radiation treatments were demonstrated to foster various degrees of restoration of thrombocyte and erythrocyte function, the efficiency depending on the period of radiation. It was after a 30 min radiation of rats that a most expressed restoration of thrombocyte and erythrocyte functional activity was observed.

Animals↗
PubMed2004

[Leveling the hyperlipidemic effect of beta-adrenoblockers by means of antiatherogenic vegetarian diet].

The purpose of the study was to examine the capacities of correction of impaired lipid metabolism in patients with CHD receiving selective beta-adrenoblockers (beta-AB) by using an antiatherogenic milk-and-vegetable diet. According to the type of antiatherogenic diet, 67 patients were divided into 2 groups: 1) 42 patients were on an antiatherogenic vegetarian diet (a vegetarian group--VG) and 2) 25 patients received routine mixed diet No. 10c (a control group--CG). At the same time all the patients received similar antianginal drug therapy including the selective beta-AB atenolol in a dose of 50 mg/day. The vegetarian diet without special hypolipidemic therapy had a marked normalizing effect on the serum lipid spectrum in patients with CHD. Thus, in VG, by the end of treatment, the level of total cholesterol significantly decreased by 16% while in the controls it increased by 13%. High-density lipoprotein cholesterol increased in VG and decreased in CG, therefore the atherogenicity coefficient considerably rose. These were true for triglycerides and very low-density lipoprotein cholesterol. These parameters significantly decreased in VG (by more than 30%) and increased in CG (by 16%). Among the clinical symptoms, a more pronounced decrease in blood pressure in the patients on vegetarian diet and a more significant increase in their exercise tolerance. Balanced antiatherogenic milk-and-vegetable diet in patients with coronary heart disease prevents the hyperlipidemic effect caused by the selective beta-AB atenolol and it is an agent for preventing its negative effect on lipid metabolism.

Adrenergic beta-Antagonists↗
PubMed2004

[Restoration of blood rheological properties by means of SWF-irradiation at the frequency of nitric oxide molecular spectrum (in vivo)].

We have investigated impact of electromagnetic SWF-oscillations at nitric oxide molecular spectrum of radiation and absorption (MSRA) on rheological blood properties of albino rats under the immobilizing stress. The SWF-irradiation was demonstrated to foster restoration of disordered rheological blood properties, its efficiency depending on the period of irradiation.

Animals↗
PubMed2004

[Effect of H2-blockers and proton pump inhibitors on intragastric acidity and intraesophageal pH in patients with gastroesophageal reflux disease].

We investigated 53 patients with GORD symptoms and a various grade (A-C according to the Los Angeles classification) of reflux oesophagitis diagnosed in the course of upper endoscopy. By using 24-hour gastric and esophageal pH-metry we investigated the antisecretory effect of single-dose morning or evening administration of famotidine, omeprazole and rabeprazole. We revealed essential superiority of single-dose morning omeprazole and rabeprazole administration in daily gastric acid release suppression and gastro-esophageal reflux prevention as compared with morning famotidine and evening omeprazole and rabeprazole administration in GORD patients.

Drug Administration Schedule↗
PubMed2004

[Roentgeno-endovascular occlusion of congenital arteriovenous fistula of the neck].

We report here a successful outcome of X-ray endovascular occlusion of congenital indirect macrofistular arteriovenous fistula between the first segment of the left subclavian artery and vertebral venous plexus with a manifested shunt into the brachiocephalic vein. Described in detail herein are the diagnosis of the disease and technical peculiarities of performing transcatheter endovascular occlusion.

Adult↗
PubMed2002

Polyaniline-modified cholinesterase sensor for pesticide determination.

Cholinesterase sensors based on glassy carbon and planar epoxy graphite electrodes modified with processed polyaniline have been developed and examined for pesticide detection. The modification of electrode surface with polyaniline provides high operational stability and sensitivity towards the pesticides investigated. The detection limits found (coumaphos, 0.002, trichlorfon, 0.04, aldicarb, 0.03, methiocarb, 0.08 mg l(-1)) make it possible to detect the pollutants in the waters on the level of limited threshold levels without sample preconcentration.

Aniline Compounds↗
PubMed2002

[Vegetarian diet in treating elderly patients with ischemic heart disease (clinico-hemodynamic, biochemical, and hemorheological effects)].

The inclusion of balanced antiatherogenis of vegetarian diet in a complex of therapeutical means of the patients of ischemic heart disease in elderly age (average age 72.3 years) promotes normalization of clinical and biochemical parameters, correction of lipid metabolism and parameters plasma hemostasis. Vegetarian antiatherogenis the diet is perspective means in treatment of the patients ischemic heart disease of elderly age.

Aged↗
PubMed2000

[Blood lipids and intensity of free radical oxidant processes in elderly patients with ischemic heart disease on antiatherogenic vegetarian diet].

The authors studied the effects of balanced antiatherogenic vegetarian diet enriched with soya bean products on blood lipids and intensity of free radical oxidant processes in elderly patients with ischemic heart disease. 45 patients with dyslipoproteinemia type IIA or IIB were examined for hemodynamic parameters, lipid spectrum and intensity of free radical oxidation. The diet promoted a trend to normalization of central hemodynamics, significantly reduced the level of atherogenic lipids in blood, improved free radical lipid peroxidation and activity of nonenzymatic antioxidant defence.

Aged↗
PubMed1999

[The effect of an antiatherogenic vegetarian diet on the clinico-hemodynamic and biochemical indices in elderly patients with ischemic heart disease].

AIM: To study the effects of newly developed antiatherogenic vegetarian diet enriched with soya bean products on clinico-hemodynamic characteristics of elderly patients with coronary heart disease (CHD). MATERIALS AND METHODS: Clinico-hemodynamic parameters, lipid blood spectrum and plasmic hemostasis were studied in 28 elderly CHD patients divided into groups by dyslipidemia type (IIA, IIB, IV). RESULTS: The antiatherogenic vegetarian diet promoted normalization of central hemodynamics, lowering of blood atherogenic lipids, positive changes in blood rheology. CONCLUSION: The proposed balanced antiatherogenic vegetarian diet proved to be an effective monotherapy of dyslipidemia in elderly patients with coronary heart disease.

Aged↗
PubMed1998

[Effects of drug therapy on serum lipids and plasma hemostasis in aged patients with ischemic heart disease on different diets].

The effects of antianginal and hypolipidemic therapy on biochemical status and plasmatic hemostasis were studied in 57 aged patients with ischemic disease. The study group (n = 19) got the vegetarian diet (VA-IIIG) enriched with soya-based products. The control 38 patients were on conventional mixed diet including meat, fish and poultry (A-1). It is shown that the vegetarian diet promotes normalization of lipid serum spectrum and plasmatic hemostasis. Inclusion of atherogenic vegetarian diet in the treatment of aged patients considerably improves the effect of antianginal and hypolipidemic therapy.

Aged↗
PubMed1994

[Surgical treatment of lung cancer in patients with preoperative radiation therapy].

Combined treatment (radiotherapy--operation) was conducted in 378 patients with lung carcinoma in 1963-1991. Retrospective analysis of the immediate and late-term results of treatment showed that preoperative radiotherapy does not complicate the operative intervention. The incidence of postoperative complications is a little higher than among nonirradiated patients. Pyoinflammatory complications prevailed. Marked postradiation damage of the tumor occurred approximately in 1/3 of the patients and depended on the total largest dose of radiotherapy. Adenocarcinoma of the lung was most resistant to radiotherapy, squamous cell carcinoma and undifferentiated carcinoma were most sensitive. Total 5-year survival of patients with lung carcinoma was 35.8% after combined treatment and 42.9% after radical operations. Among patients with complete regression of the tumor after preoperative radiotherapy 63.2% of patients who underwent operation had a survival period of over 5 years.

Adenocarcinoma↗