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Biomedical subjects

A N El'kov

Publications and source records attributed to A N El'kov.

14 recordsLinked to original sources
PubMed1999

[The dynamics of blood serum middle-molecule peptides in the prognosis of the course of acute pancreatitis].

The work is devoted to studying the dynamics of endogenous toxemia by the level of middle mass peptides of blood serum in patients with acute pancreatitis. The level of middle mass peptides was investigated in 116 patients spectrophotometrically after Gabriélian with the wave length 254 nm (1st fraction, MMP-1) and with the wave length 282 nm (2nd fraction, MMP-2). It was found that the ratio of these fractions could be used as a prognostic index of the complicated course of acute pancreatitis. When the initial ration MMp-2/MMP-1 is less that 1 the risk of the development of complications of the second phase of acute pancreatitis is real. The decrease of the level of MMP-1 and MMP-2 during treatment by the 3rd-4th days is considered to be an indicator of the favorable outcome of the disease. The elevation of the level of MMP-1 and MMP-2 by the 3rd-4th days despite the treatment predicts an unfavorable outcome of the disease.

Acute Disease↗
PubMed1991

[Predicting the probable passage of common bile duct calculi in patients with mechanical jaundice].

The authors propose a mathematical method of predictingthe passage of common bile duct calculi. An original mathematical formula derived by a computer allows a 98% accuracy of the prognosis. The estimations were based on the principal parameters influencingthe choledochal calculi movement defined with the help of the regression analysis. Such prediction simplifies the choice of therapeutic policy in mechanical jaundice due to choledocholithiasis.

Aged↗
PubMed1988

[Predicting the duration of functioning of iliac artery prostheses].

A formula has been computer-derived to predict the duration of the operation of lavsan vascular prostheses, implanted in the iliac artery. The relative mean-square prognostic error is 2.8%. The formula outlines more specific indications for the implantation of iliac arterial prostheses.

Adult↗
PubMed1987

[Predicting early postoperative thrombosis of vascular prostheses in aorto-femoral position].

Twenty nine factors influencing the function of vascular prostheses were studied in 100 patients. Five parameters were found by computation allowing the formula for prognosis of early thrombotic complications to be built in patients after reconstructive operations of aorto-femoral prostheses. These parameters are: resistance of the distal vascular bed to blood flow, length and diameter of the profound femoral artery, length and diameter of the vascular prosthesis. The accuracy of prognosis was 92%.

Aorta, Abdominal↗
PubMedDate not supplied

[Detoxicating effects of physico-chemical hemotherapy in acute exogenous poisoning].

Physical factors (magnetic fields and UV and laser exposure) improve the blood status and sodium hypochlorite therapy accelerates removal of exo- and endogenic toxic substances from the organism, as was demonstrated in more than 1200 patients with various intoxications. These effects are due to activation of the detoxication systems of the organism and more rapid removal of some toxic agents from the blood during hemoperfusion. Adequate dosing of these exposures by means of clinical dosimetry will improve the efficacy and safety of detoxication.

Acute Disease↗
PubMedDate not supplied

[Disorders of lipid peroxidation processes and blood antioxidant system in acute poisoning with psychotropic drugs].

Study of lipid peroxidation (LPO) processes and antioxidant defense (AOD) system of the blood in 96 patients with psychotropic drug poisoning of different severity showed disorders in the LPO/AOD system irrespective of the initial level of chemical injury. These disorders are characterized by imbalance in the ratio of LPO and AOD components. The severity and direction of these disorders depend on the severity of intoxication and poison exposure in the body before treatment measures, which dictates correction of these disorders with consideration for individual LPO and AOD parameters.

Acute Disease↗
PubMedDate not supplied

[Effect of sodium hypochlorite on neuroregulatory systems in acute psychotropic drug poisoning].

The effect of sodium hypochlorite (SHC) on neuroregulatory systems was studied in patients with acute poisoning with psychotropic drugs infused intravenously as components of infusion therapy. Infusion therapy alone or in complex with SHC does not affect the cholinergic system of the organism. The corrective effect of SHC on the sympathetic, serotonin- and histaminergic systems was more pronounced in comparison with infusion therapy and was the most expressed on day 2 after the treatment.

Acute Disease↗
PubMedDate not supplied

[Expert criteria of the degree of severity of the chemical trauma in acute poisonings by organophosphate insecticides].

The article deals with quantitative assessment of severity of chemical trauma (according to life-threatening characteristics) in case of acute peroral poisoning with OPI (carbophos and chlorophos). Standard diagrams were plotted which help to assess the life threatening values of the given compounds depending on the initial blood poison level or recorded decrease in enzyme cholinesterase activity. Basic opportunity to assess severity of body lesions in case of poisoning with OPI according to character of specific clinical signs was evidenced.

Acetylcholinesterase↗
PubMedDate not supplied

[Changes in the ratio of formed elements of the blood in acute exogenous poisoning in children].

In order to estimate the informative value of the leukocytic index of intoxication and the neutrophil to lymphocyte ratio in the assessment of the status of children with acute poisonings, the authors analyzed 223 hemograms of 189 children aged 1 to 15 with different types of acute poisonings. The results indicate that these parameters are nonspecific, their values depend on the severity of the patient's status and are unrelated to sex, age, and type of poisoning; a correlation between the concentration of the toxic agent in the blood and hemogram parameters has been confirmed.

Acute Disease↗