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Biomedical subjects

A Murphy

Publications and source records attributed to A Murphy.

171 records · Page 10Linked to original sources

The use of basic life support kits in general practice.

Donegal is a predominantly rural area with many general practices situated considerable distances from a district hospital. Fifty Life Support Kits were supplied to General Practitioners by the Donegal Pre-Hospital Emergency Care Project in 1995 following appropriate training. This is a survey of the use of items in these kits. To determine the frequency of use of the equipment, the type and location of the incidents, the kit items utilised and patient outcome. Retrospective questionnaire survey of 49 participating GPs. 208 patient incidents were described by 46 doctors (average 4.5 per doctor) Most incidents were outside the surgery (88.24%). Road Traffic Accidents (36%) were the commonest reason for use, followed by cardiac emergencies (28%), other medical emergencies (14%) and other trauma (11%). All items except the burns sheet had been used. The most used items were cannulae, (64.7% of incidents) and fluids (50.9% incidents). Other useful items were emergency drugs, dressings, collars, airways, suction and torch. Regarding outcome, 162 patients required hospital transfer and 25 died. Eleven did not require hospital treatment. The participating doctors judged that the basic life support kits positively contributed to outcome in 79.4% of cases described. Basic Life Support kits contribute to the pre-hospital care of patients when used by GPs with immediate care training.

Accidents, Traffic↗

Measurement of total fructan in foods by enzymatic/spectrophotometric method: collaborative study.

An AOAC collaborative study was conducted to evaluate the accuracy and reliability of an enzyme assay kit procedure for measuring oligofructans and fructan polysaccharide (inulins) in mixed materials and food products. The sample is extracted with hot water, and an aliquot is treated with a mixture of sucrase (a specific sucrose-degrading enzyme), alpha-amylase, pullulanase, and maltase to hydrolyze sucrose to glucose and fructose, and starch to glucose. These reducing sugars are then reduced to sugar alcohols by treatment with alkaline borohydride solution. The solution is neutralized, and excess borohydride is removed with dilute acetic acid. The fructan is hydrolyzed to fructose and glucose using a mixture of purified exo- and endo-inulinanases (fructanase mixture). The reducing sugars produced (fructose and glucose) are measured with a spectrophotometer after reaction with para-hydroxybenzoic acid hydrazide. The samples analyzed included pure fructan, chocolate, low-fat spread, milk powder, vitamin tablets, onion powder, Jerusalem artichoke flour, wheat stalks, and a sucrose/cellulose control flour. Repeatability relative standard deviations ranged from 2.3 to 7.3%; reproducibility relative standard deviations ranged from 5.0 to 10.8%.

Borohydrides↗

Duplication (12p) syndrome--a family.

We report the following cases of Duplication (12p) Syndrome. This is a rare entity which may present with developmental delay, dysmorphic features and malformations.

Chromosome Aberrations↗

Cleansing solution.

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Administration, Cutaneous↗