Search PubMed⌕ Search

Biomedical subjects

A Mrabet

Publications and source records attributed to A Mrabet.

At least 37 records · Page 2Linked to original sources
PubMed1995

[Cerebral venous thrombosis and arterial infarction in pregnancy and puerperium. A series of 60 cases].

We report a retrospective study of 60 patients aged from 18 to 46 years, pregnant or parturient, with ischemic cerebrovascular accident. The hospital incidence was 3.6 cases per year. The prevalence was 0.70 per 1,000 childbirth in Tunis area. 3/4 of these cerebrovascular accidents occurred in the post partum period and 1/4 in the pregnancy. Gravidic toxemia and sepsis were the most frequent risk factors. The cerebral venous thrombosis (CVT) (55%) were almost as frequent as cerebral ischemic accidents (CIA) 45). We individualized 3 groups of CVT: septic, aseptic, mixed. Among CIA etiologies we noted two cases of cerebral angiopathy of toxemia and one case of peripartum angiography. The mortality rate nul for CIA, was 36% for CVT. The functional sequelae were more severe for CIA.

Adult↗
PubMed1994

[Bilateral infarction of the caudate nuclei].

We report the case of a 57-year-old right-handed woman, with a history of hypertension, who, in February 1990, suddenly developed behavioral and cognitive abnormalities. Prior to the onset of her illness she had been normal. On examination, neuropsychological testing (Wechsler Mental Test, Wechsler Adult Intelligence Scale Revised, Knox Cube Test) elicited attention abnormalities, decreased recent memory, apathy, reduced spontaneity and initiative and left hemiparesia. CT scan showed small low density areas in the head of both caudate nuclei and right internal capsule, indicating infarction. Two years later, the deficit had partially resolved. Apathy persisted; psychometry showed an IQ of 57. Bilateral damage to the head of the caudate nuclei disrupt cortical-subcortical connections. The caudate nucleus is an essential component of basal ganglia-thalamo-cortical circuitry and its contribution to cognitive functions and behavior appears to be important.

Caudate Nucleus↗
PubMed1994

[Type 1 neurofibromatosis in Tunisia: 66 cases].

A multidisciplinary transversal descriptive study was conducted from June to October 1992 to determine the clinical manifestations and laboratory findings observed in 66 patients with type 1 neurofibromatosis. Diagnostic criteria were those of the National Institute of Health as recommended for subjects over 20 years of age. All patients over the age of 25 had café au lait spots, neurofibromas, lentigines and nodules. Occurrence of lesions of the central nervous system was significantly earlier than peripheral nervous manifestations. The optic glioma was the most frequent lesion of the central nervous system. Complications were observed during the first twenty years of the disease. Based on these findings, we propose a clinical and laboratory work-up designed as a function of age.

Adolescent↗
PubMed1993

Prevalence study of neurologic disorders in Kelibia (Tunisia).

A full-scale survey, in Kelibia, Tunisia, screening 34,874 persons started on July 1, 1985. The accuracy of this survey was evaluated by a second survey using a randomized sample of 1,673 subjects (control survey). Better selection and training of the interviewers during the control survey led to a higher positive predictive value with no modification in prevalence ratios of neurologic disorders. The control survey helped to validate the full-scale survey data which were then used to establish the prevalence ratios of major neurologic disorders in Kelibia. Prevalence ratios, age-adjusted to the WHO population, were compared to those of studies using similar methodology. Migraine prevalence ratios in Nigeria, Ecuador, and Kelibia were equivalent. Epilepsy and Parkinson's disease prevalence ratios were close to those of other similar studies. The stroke prevalence ratio was low, compared to other studies, but was not the lowest. It seems that in Kelibia, stroke does not constitute a public health problem as it does in the USA or urban China. The large full-scale survey, in Kelibia, provided estimates of prevalence ratios for stroke, epilepsy, migraine and other common neurologic disorders for comparisons with other countries. However, definitions of neurologic disorders and diagnostic criteria differ from one study to another making difficult the comparison of results between different countries. Had the WHO protocol developed well-defined criteria and a standardized neurologic examining tool, more accurate comparisons could have been made.

Adult↗
PubMed1993

[Value of cerebral tomodensitometry in Behcet's disease with neurological manifestations (50 cases)].

The authors report a retrospective study of 50 CT Scan made for patients suffering from Behçet's disease with neurological manifestations. Neuro-Behçet can affect all the central nervous system structures with particular predilection to the brain stem, internal capsula and basal brain ganglia. The authors emphasize on the importance of CT Scan for the diagnosis, the severity evaluation of the neurological impairment and for the Neuro-Behcet's prognosis.

Behcet Syndrome↗
PubMed1993

[Extended melanocytic tumor of the cervical spine. Apropos of a case of melanotic schwannoma].

A case of melanotic tumour was described localized close to the right cervical spine, destroying C6 and C7 vertebral bodies and pedicles, on a 27 years old woman. Histological and immunohistochemical findings, correlated with clinical and X-rays data, led up to the diagnosis of a melanotic schwannoma. Six years after the beginning of the illness, the outcome was preceded by a local vertebral involvement without metastasis and paradoxically with a good general state. The tumoral localization and the finding of nervous structures allowed to evoke a development from a cervical nerve root. On histological basis, we propose to classify this tumour along the new concept described by the Mayo Clinic pathologists team, under the name of psammomatous melanotic schwannoma. Some authors evoke a congenital outset in a context of endocrine disorders.

Adult↗
PubMed1993

[Osteoid osteoma of the spine. Radiological study of 21 cases].

Spinal osteoid osteomas are rare. We report 21 cases, that have been studied and treated since 1985. The tumor affects young people, who are less than 25 years old. The pain is the most common sign. Diagnosis is difficult, but can be made by radiology. X ray sometimes enables to suspect the diagnosis. Scintigraphy shows a focus hyperfixation more suggestive. Computed tomography enables the diagnosis by showing a bony lacuna surrounded by osteosclerosis. Moreover, computed tomography localizes very well the nidus of the osteoid osteoma, and guides the surgical treatment. Since computed tomography, other techniques like angiography and tomography are less used for diagnosis.

Adolescent↗
PubMed1992

[Cervicobulbar intramedullary lipoma. Apropos of a case with review of the literature].

The authors report a case of cervical intramedullary lipoma extending into the bulbomedullary junction. 99 cases of cervical and/or dorsal intramedullary lipomas without spinal dysraphism, reported since 1884, are reviewed. There is poor correlation between lipoma's length and age of onset. Only lipoma extended to all the spinal cord begin in the first years of life. Clinical presentation is in 58% of cases a slowly compressive myelopathy, a syringomyelic syndrome in 9.5% of cases, a Brown Sequard syndrome in 6.5% of cases or atypical clinical features in 26% of patients. Finding of a subcutaneous lipoma at the level of the lesion helps for diagnosis. C.T. scan and magnetic resonance imaging (M.R.I.) precise lipomatous constitution of the tumor, its limits and relations with neighbouring tissues. Surgery is necessary when clinical features are advanced. Surgery indication is debatable when neurological manifestations are poor or absent. Post operative course is generally good and is not related with type of intervention.

Brain Neoplasms↗
PubMed1991

The care of the limb deficient child in north Africa.

The surgical and prosthetic treatment of longitudinal lower limb deficiency is described and discussed, in the light of cultural and social requirements. Those with upper limb deficiencies are not fitted with prostheses.

Adolescent↗
PubMed1991

[Clinical and electrophysiological study of 2 familial cases of Marcus Gunn phenomenon].

Two cases of jaw-winking synkinesia or Marcus Gunn (MG) phenomenon are reported, with electromyographic and genetic studies. In the first patient a right eyelid ptosis which had been occurring since birth was associated with a bilateral MG phenomenon confirmed by electromyography. An examination of other family members revealed 3 other cases in the mother's family. The second patient had a congenital left eyelid ptosis associated with an MG phenomenon. His maternal uncle and his mother also had this "jaw-winking" synkinesia. The authors discuss the physiopathology of this complex phenomenon up to now without known neurological lesions. Concerning the genetic aspect of the MG phenomenon, they conclude that in their patients the hereditary pattern was that of an incomplete autosomal dominant trait with varied expressivity in the two families.

Adolescent↗
PubMed1990

[Epidemiologic aspects of cerebrovascular accidents in Tunisia].

We report the results of 3 epidemiological studies of stroke in Tunisia. In Tunis urban population, the crude annual incidence rate of stroke has been estimated at 0.54/1,000 and the prevalence rate at 6 to 14/1,000. The incidence rate adjusted to population at risk (greater than or equal to 45 years old), is around 1.92/1,000. A door-to-door survey conducted in Kelibia, according to a WHO protocol, showed a prevalence rate of 7.2/1,000 when adjusted to population at risk. CT diagnosed infarction and haemorrhage and excluded non-stroke cases (10 p. 100). Cerebral haemorrhage was more frequent than in other published studies (28 p. 100).

Adolescent↗
PubMed1989

[2 cases of vascular syndrome of the cranial nerves of ischemic origin].

The authors report the cases of two patients who had sudden unilateral alternating and regressive attacks of the cranial nerves. The first patient, a 63 year old diabetic woman, suffered regressive paralysis of the right third nerve, followed two months later by paresthesia of the same side of the face, accompanied by difficulty in swallowing and dysarthria. Six months later, she developed a right facial paralysis while pharyngeal and lingual involvement entirely disappeared. Right carotid angiography revealed stenosis of the middle meningeal artery. Nine months later she developed left-sided ophthalmoplegia followed by a homolateral facial paralysis. The second patient, a 24 year old woman, developed homolateral regressive attacks of the II, V, VII and VIIb, and VIII nerves during recovery from herpes zoster of the right geniculate ganglion. Doppler studies showed inversion of the flow in the right ophthalmic artery. The pathogenesis of these multiple paralyses of the cranial nerves is discussed, a possible cause being ischaemic attacks of the vascular territories of the cranial nerves.

Adult↗