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Biomedical subjects

A Morrell

Publications and source records attributed to A Morrell.

6 recordsLinked to original sources
PubMed2001

A nationwide survey of post-operative instructions following uncomplicated phacoemulsification cataract surgery.

PURPOSE: To determine the heterogeneity of post-operative instructions following uncomplicated phacoemulsification cataract surgery. METHODS: A survey was sent to a random sample of 115 cataract centres in the United Kingdom. Eighty questionnaires were returned, corresponding to a response rate of 70%. RESULTS: The time at which post-operative advice was given, the nature of post-operative problems, and advice regarding the instillation of post-operative eye drops were all very similar among centres. There was mild variability among centres in the advice given on post-operative analgesia, eye cleaning and hair washing. However, there were marked differences in the advice given to patients regarding how long an eyeshield should be worn, and also regarding daily activities such as lifting objects and driving. Thirty-five per cent of centres adopted a single post-operative review. No centre had more than three post-operative reviews for an uncomplicated phacoemulsification. The final refraction was conducted by at least 30% of centres within the first month, and by at least 92% within 2 months. CONCLUSIONS: Phacoemulsification with a self-sealing tunnel is now the technique of choice for an uncomplicated cataract extraction and is increasingly conducted on a daycase basis. However, our survey reveals that there is considerable heterogeneity in the postoperative instructions given to patients following this procedure, and we would suggest that considerable benefits would result from further work in this area. Standard guidelines would not only benefit the patient in terms of improved patient education and rehabilitation, but would also result in economic benefits from reduced post-operative visits.

Humans↗
PubMed2000

Creating a hospital-based nursing research fellowship program for staff nurses.

Staff nurses are expected to participate in nursing research and to use study findings. Insufficient institutional support and uncertainties about how to participate in the research process can prevent staff nurses from meeting these expectations. We describe a newly developed nursing research fellowship program designed for staff nurses who practice in an acute care setting. An overview of the entire curriculum and the outcomes of the first year of the program are described.

Curriculum↗
PubMed1996

Successful medical therapy of Acanthamoeba keratitis with topical chlorhexidine and propamidine.

INTRODUCTION: Following laboratory studies on new potential chemotherapy for Acanthamoeba keratitis, when chlorhexidine and propamidine provided an additive in vitro effect, a series of 12 patients with culture-proven Acanthamoeba keratitis from three UK centres was monitored during and after therapy. METHODS: In all cases the clinical diagnosis was confirmed by amoebal culture. In some instances identification of the protozoa by direct microscopy of corneal tissue was possible. The medication was provided topically in drop form until the keratitis had resolved. In vitro sensitivity to chlorhexidine and propamidine was performed on all isolates and compared with sensitivity to a range of other drugs used for treatment of the infection. RESULTS: In vitro drug testing confirmed that trophozoites and cysts of all 12 Acanthamoeba isolates were fully sensitive to chlorhexidine and propamidine. Therapy was satisfactory for controlling and eradicating the acanthamoebal infection in all patients. Three patients developed discrete stromal infiltration at the site of infection that resolved 1 week after commencing therapy, with or without use of steroids. Two patients developed a late inflammatory effect in the stromal scar at 6 months, which resolved with steroids. No clinical evidence of chlorhexidine toxicity was found in any patients. CONCLUSIONS: The combination of topical chlorhexidine and propamidine was very effective for treating Acanthamoeba keratitis provided the drugs were continued for a sufficient period. No drug toxicity or resistance of Acanthamoeba isolates was observed in the 12 treated patients.

Acanthamoeba↗
PubMed1991

Ocular chromatic aberration and age.

The amount of longitudinal chromatic aberration in groups of younger and older subjects is compared in three separate studies, using a laser speckle optometer, Badal optometers with monochromatic illumination, and monochromatic retinoscopy. No evidence is found for any systematic change in chromatic aberration with age.

Adult↗
PubMed1987

A bichromatic laser optometer.

A laser refractive technique involving the simultaneous viewing of red (633 nm) and green (514 nm) speckle patterns has been investigated. The speckle patterns are displayed on adjacent, contra-rotating drums with a common axis, the refractive status being determined by matching the apparent speckle speeds for the two wavelengths. The refractive corrections found are compared with those determined by making either red or green speckles appear stationary, and with the independently determined results of conventional subjective refractive procedures. It is concluded that, although the bichrome technique is feasible, most subjects found the conventional laser method, involving red speckles alone, easier to use and that the associated results were slightly more reproducible.

Adult↗