Biomedical subjects

A Morimoto

Publications and source records attributed to A Morimoto.

184 records · Page 11Linked to original sources

PubMedDate not supplied

The impact of race on tooth formation.

The subjects consisted of 650 children (American white 245, Chinese 202, Japanese 203) from five to twelve years old, who came to the Department of Growth & Development, University of California, San Francisco. Mandibular first molar development was determined by inspecting panoramic radiographs and assigning a rating according to Kullman's method, which classifies tooth formation into seven stages according to growth and development. The samples in each age-stage were evaluated by their means values. Tooth formation was significantly more advanced in the American white children than in the Chinese or Japanese at all stages. The significance of the difference between Chinese and Japanese children was not identified. Tooth formation was shown to be highly correlated with chronological age, with a coefficient of more than 0.7 in all racial groups.

Age Determination by Teeth↗

PubMedDate not supplied

The hemodynamics of dysplastic nodules in the liver evaluated by CT angiography and immunohistochemistry.

BACKGROUND/AIMS: Dysplastic nodules diagnosed pathologically exhibit various hemodynamic patterns. To evaluate these differences in their hemodynamics, we observed basement membrane formation of sinusoids. METHODOLOGY: For 12 low-grade dysplastic nodules, 24 high-grade dysplastic nodules and 16 hepatocellular carcinomas, both computed tomography during arterial portography and CT arteriography were performed preoperatively. Resected specimens were examined immunohistochemically for COL IV (type IV collagen) and laminin to observe basement membrane formation. We compared their hemodynamics on computed tomography during arterial portography and CT arteriography with the expressions of COL IV and laminin. RESULTS: All of the low-grade dysplastic nodules were not hypervascular on CT arteriography, and negative for COL IV and laminin. All of the hepatocellular carcinomas were hypervascular on CT arteriography, and positive for COL IV and laminin. High-grade dysplastic nodules exhibit four hemodynamic patterns on CT during Arterial Portography/CT arteriography. All of 7 iso/iso and 5 iso/hypo nodules were negative for COL IV and laminin. Of the 9 hypo/hyper nodules, which exhibited hemodynamics similar to hepatocellular carcinoma, COL IV was identified in 7 and laminin identified in 8 nodules. Of the 3 hypo/hypo nodules, COL IV and laminin were identified in one. CONCLUSIONS: In high-grade dysplastic nodules, most cases exhibited a correlation between the hemodynamic patterns and the degree of the sinusoidal basement formation.

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PubMedDate not supplied

Intra-arterial digital subtraction portography with a blood-isotonic, non-ionic, dimeric contrast medium.

Intra-arterial digital subtraction portography (IA-DSP) with a blood-isotonic, non-ionic, dimeric contrast medium was carried out in 27 patients with hepatocellular carcinoma. It was possible to obtain images of excellent or good quality of the portal vein and its bilateral main branches in all patients. The third-order branches of the portal vein in the right lobe could be identified in all patients, and images of excellent or good quality were obtained in a mean of 80.2% of patients. Images of third-order branches in the left lobe were of lower quality than those of third-order branches in the right lobe; in particular, images obtained were of poor quality for 27.3% of the medial branches of the left lobe. It was impossible to identify the caudal branches in almost all patients. The side effects of IA-DSP, pain and sensations of heat were very mild: only one patient complained of mild pain, while 18 patients (69.2%) complained of no sensations of heat whatsoever.

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PubMedDate not supplied

Tolerance of chronically-diseased liver to prolonged hemihepatic ischemia during hepatectomy.

Seventeen patients with chronic liver disease underwent prolonged warm ischemia of hemi-lobe during liver resection. Those included 15 cirrhotic patients and two with chronic hepatitis. The hemi-hepatic ischemia was carried out with a liver clamp. The normothermic liver ischemia time of 40 to 70 minutes (53.8 +/- 10.4 minutes, mean +/- SD) were tolerated well with an acceptable postoperative course and no mortality. The liver with cirrhosis or chronic hepatitis can tolerate a hemi-hepatic ischemia of up to 70 minutes for patients with no high-risk factors.

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