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Biomedical subjects

A Morello

Publications and source records attributed to A Morello.

83 records · Page 5Linked to original sources
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Methoprene and hydroprene are metabolized by ester cleavage in isolated hepatocytes.

Methoprene (isopropyl [2E,4E]-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate) and hydroprene (ethyl[2E,4E]-3,7,11-trimethyldodeca-2,4-dienoate) are actively metabolized, mainly to their corresponding acids by isolated rat hepatocytes and rat liver subcellular fractions. Small amounts of conjugates corresponding to glucuronides are also found. The esterase activity is of microsomal origin and is almost completely inhibited by tri-o-tolyl phosphate in isolated hepatocytes and microsomal fractions supplemented with NADPH. No evidence for the participation of the NADPH-dependent cytochrome P-450 system in the metabolism of either compound was observed.

Animals↗
PubMedDate not supplied

[Sciatica: an open problem].

The Authors believe it erroneous to consider disc herniation as the only pathology responsible of sciatalgia. They emphasize the importance of proper diagnostic investigation prior to any operative intervention.

Adult↗
PubMedDate not supplied

[Adaptable and portable cephalometric devices: a new method in obtaining cephalometrics].

Cephalometric radiographic explorations are widely recommended in the diagnosis of the obstructive sleep apnea syndrome (OSAS). In order to improve their diagnostic value, its practice in the upright and supine position has been proposed. A rigorous practice of cephalometric requires the employment of cephalometric devices in order to assure a correct positioning of the head and provide reliable X-ray pictures, comparable within reasonable accuracy over a period of time. The commercialized cephalostats are often expensive due to the structural conditions needed for their development and usually they not allow the simultaneous practice of upright and supine cephalometric. In this paper we describe a cephalometric adaptable device, developed by our research group, that may solve such problems.

Cephalometry↗
PubMedDate not supplied

[Carotid paraganglioma: a case report].

Carotid paraganglioma are tumors arising from chemoreceptor paraganglioma cells. These cells have proved to have an embryologic origin from the neural crests. Due to their low incidence these tumors are not an habitually found in daily practices. We present a case of carotid body paraganglioma diagnosed by clinical exploration, CT scan, magnetic resonance imaging and magnetic resonance angiography which was successfully treated by surgery. The diagnostic and therapeutic difficulties present in these tumors are discussed.

Angiography↗
PubMedDate not supplied

[Neurosensory hearing loss associated with ischemic heart disease. Features and prognostic values].

The aim of this study was to verify the supposed pathological hearing loss in those patients with ischemic heart disease, as well as to determine its features and possible clinical usefulness. Two groups were made: group A (n = 65), patients admitted for acute episode of ischemic heart disease, group B (n = 60), patients without cardiac or auditive disorders. Auditive assessment included standard PTA and Bera. Cardiologic evaluation was made through cardiac catheterism with coronariography. Results confirm the existence of a clinical association between "perceptive hearing loss" and "ischemic heart disease", independently of the age, with a characteristic pattern of hearing loss, and also show the existence of a high risk subgroup within the population with coronary risk.

Acute Disease↗
PubMedDate not supplied

[Topographic diagnosis of hearing loss in patients with ischemic heart disease. Use of high-rate brain stem evoked response audiometry].

Hearing loss in patients with ischemic heart disease traditionally has been attributed to atheromatous cerebral vascular disease. In this study, the site of the auditory lesion was sought in patients with ischemic heart disease and perceptive hearing loss. Standard brainstem evoked response audiometry (BSER) with increased stimulation rate (ISR) were performed. Sixty-seven patients admitted for coronary artery disease were examined. Fifty-seven recordings were complete and evaluable. All the cases of hearing loss were endocochlear. In 4 patients. BSER and ISR detected subclinical retrocochlear lesions that were compatible with ischemic disease. The results suggest that selective early cochlear ischemia can occur in young persons with heart disease. The sensitivity of BSER with ISR for detecting ischemic brainstem lesions was confirmed.

Adult↗
PubMedDate not supplied

[Surgical multiple level reconstruction of the upper airways for treatment of obstructive sleep apnea. Two clinical cases].

Techniques for surgical correction of the soft palate are used commonly to treat obstructive sleep apnea syndrome (OSAS), but a satisfactory cure cannot be ensured because such techniques usually involve localized correction of the upper airways (UA) whereas UA collapse during sleep involves the entire length. The development of correction techniques for the entire extension of the UA may help to solve this problem. We report the first two cases of multilevel UA surgical reconstruction in OSAS performed in Spain. The excellent results obtained favor routine use of this type of surgery once it has been validated in clinical practice.

Adult↗
PubMedDate not supplied

[Phyolaryngocele: a case report and review of literature].

A case of pyolaryngocele presented as a lateral cervical mass that produced acute dyspnea requiring tracheotomy. The diagnosis was by direct laryngoscopy, which revealed outflow of purulent material with pressure on the tumor, and was confirmed by CT. Broad-spectrum antibiotic treatment was given and the pyolaryngocele was excised by lateral extramucosal tyrotomy. The literature on laryngocele and pyolaryngocele was reviewed.

Escherichia coli↗