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Biomedical subjects

A Moragas

Publications and source records attributed to A Moragas.

At least 37 records · Page 2Linked to original sources
PubMed1986

Acute form of visceral leishmaniasis in a 3-month-old infant.

The case of a 3-month-old infant who died with an acute form of visceral leishmaniasis is reported. The liver presented an unusual pattern with widespread patchy cellular necrosis besides marked reticulin proliferation and some fibrosis. The marked systemic histiocytic proliferation contrasted with the paucity of Leishman-Donovan bodies, responsible for the negativity of two bone marrow aspirates and a needle biopsy of the liver. Visceral leishmaniasis must be considered in the differential diagnosis of cholestatic syndromes in infancy.

Biopsy, Needle↗
PubMed1985

Brown adipose tissue changes in anencephalic infants. Image analysis study.

Perirenal brown adipose tissue was studied in 49 liveborn anencephalic infants of appropriate weight, whose lifespan ranged from 2 hours to 6 days. An additional series of 187 full-term infants was used as control. Morphological evidence of active and marked BAT lipolysis was found in large number of anencephalic infants suggesting that activation of BAT metabolism leading to lipolysis in the newborn does not depend on a diencephalic pathway but on peripheral mechanisms. Image analysis study did not sustain significant differences in the intrauterine storage of lipids in brown adipose tissue cells for the anencephalic and control infants who died within 24 hours of birth.

Adipose Tissue, Brown↗
PubMed1983

Multicentric giant follicular lymph node hyperplasia. Favorable response to radiotherapy.

Angiofollicular lymph node hyperplasia is a disease of unknown etiology in which two distinct histologic forms are recognized: the hyalin vascular and the plasma-cell types. Up to the current time only a few multicentric cases have been described. The authors describe an unusual case of the multicentric type, which furthermore showed an excellent response to low dosis radiotherapy. Complete, lasting remission was induced and the patient became asymptomatic.

Aged↗
PubMed1983

Morphogenesis of pulmonary veno-occlusive disease in a newborn. Image analysis study.

A 9-day-old girl was admitted to hospital because of respiratory distress. The girl died on the 11th day of life shortly after an haemodynamic study and the autopsy disclosed a pulmonary veno-occlusive disease with lesions in relatively early stages of development. Morphological pattern and computerized image analysis data induce to rule out a thrombosis as a previous event to the development of fibrotic changes and point to a "primary" intimal involvement, presumably triggered by an endothelial injury, determining a myxoid change of the intima and leading to a cellular proliferation and ultimate fibrotic occlusion of the small pulmonary veins. Apparently the lesions progress from the smaller pulmonary veins to the larger ones, in which the involvement is focal in character and related to the openings of collateral branches. The homogeneous character of the more recent lesions in the larger veins is in contrast to the heterogeneity of the fibrotic process in the smaller ones.

Female↗
PubMed1983

Prenatal development of brown adipose tissue in man. A morphometric and biomathematical study.

In a series of 110 liveborn infants who died within 24 h of birth, and six 14- to 17-week-old fetuses, the development of perirenal brown fat was studied by morphometric and biomathematical methods. Brown fat was present at the 20th week of age and, taking as index of maturity the population of multilocular adipocytes, its development progressed according to a 3-parametric logistic growth function, with a half-time of 26 weeks and a tendency to asymptotic stabilization by the 35th week. Unilocular adipocytes appeared early and their low percentage (10.9%) remained relatively stable. Brown fat development in 75% of the cases of small-for-dates corresponded to that of infants with matched postconceptional age but appropriate birth weight. Abnormal cases presented whether a persistence of immature patterns or an unusual predominance of unilocular cells. No changes due to lipolysis were detected in any case.

Adipose Tissue, Brown↗
PubMed1981

Alveolar exudation versus leukocyte aspiration in congenital pneumonia.

Alveolar leukocyte population was studied by means of image analysis techniques in 110 autopsies of infants who died of congenital pneumonia. Considering the short span-life of polymorphonuclear leukocytes and their morphological regressive changes, the working hypothesis established was that an alveolar leukocyte population constituted of immature or young forms would probably correspond to leukocyte exudated in situ rather than emigrated from the chorioamnional blood vessels towards the amniotic fluid and ultimately inspirated into the lung. For the group 0-6 hours of age two completely separated populations of cases were found, 85% of them probably corresponding to true intrauterine pneumonias and the remaining 15% to cases of inspiration of polluted amniotic fluid. In the 6-12 hour period, intermediate cases appeared and a depopulation of the initial clustering of active cases was evident. In the infants who died between 12 and 24 hours a new clustering of active cases appeared suggesting an infection acquired during the process of birth or immediately after.

Autopsy↗
PubMed1981

Hepatitis in exanthematous mediterranean fever.

In 38 patients suffering from rickettsiosis caused by Rickettsia conorii (Mediterranean Exanthematous Fever), hepatic involvement was studied via laboratory tests and in 26 cases by means of liver biopsy. SGOT, SGPT and alkaline phosphatase were found to be elevated in more than half of the patients (SGOT 74.4 +/- 93 U.K., SGPT 82.2 +/- 93 U.K., a.p. 58 +/- 21 mU/ml). In 14 patients, liver biopsy showed the existence of inclusion corpuscles in Kupffer's cells. Electron microscopic study demonstrated the existence of phagosomes inside the epithelioid cells, which, however, were difficult to categorize. The frequent existence of granulomatous hepatitis in this rickettsiosis was confirmed, while the presence of the infecting agent in the liver could not be established.

Alanine Transaminase↗
PubMed1980

Management of primary testicular tumors in children.

Between 1966 and 1977, 16 primary testicular tumors (PTT) were treated at the Social Security Children's Hospital in Barcelona. Treatment consisted of resection of the testis, vas deferens and spermatic vessels followed, when the peroperatory biopsy revealed malignancy, by para-aortic lymphadenectomy in 11 of the 13 patients with primary malignant testicular tumors (PMTT). Retroperitoneal radiation therapy was given to patients with positive paraaortic nodes. Chemotherapy was given to all patients with the PMTT. 77.0% of the thirteen patients with PMTT are alive from 1 to 11 yr after surgery. 81.3% of the 16 patients with 13 malignant and 3 benign tumors are alive.

Child↗