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Biomedical subjects

A Mombelli

Publications and source records attributed to A Mombelli.

83 records · Page 5Linked to original sources
PubMed1989

Diagnostic problems of periodontitis-like lesions caused by eosinophilic granuloma.

Eosinophilic granuloma is the localized and mildest form of histiocytosis X. It is a destructive osseous lesion characterized by large numbers of eosinophils and histiocytes. The etiology of the disease is unknown. Frequently the jaws, including the periodontium, are involved and the disease stimulates severe localized periodontitis. A case of eosinophilic granuloma of the jawbone is presented. The pertinent clinical features are emphasized and possible problems in the interpretation of clinical periodontal features are discussed.

Adult↗
PubMed1989

Wolinella recta and spirochetes in relation to alteration of probing depth in a population without regular dental care.

The purpose of this study was to determine the occurence of spirochetes and Wolinella sp. in untreated, nonselected subjects and to relate the presence of these organisms to changes in probing depth over a period of 180 days. Clinical parameters were recorded and subgingival microbial samples were taken mesiobuccally on the upper first molars of 120 subjects (mean age 37 +/- 14 years) with a history of no regular dental care. The number of motile rods and spirochetes were determined in the darkfield microscope. The samples were cultured anaerobically on a selective medium which favoured the growth of Wolinella sp. The grown microorganisms were submitted to a number of tests for the identification of W. recta. Of the 172 sites investigated longitudinally, 73 harboured motile rods, 45 harboured W. recta and 88 harboured spirochetes. 13 sites showed an increase in probing depth of greater than or equal to 2 mm. A multiple regresssion analysis revealed no statistically significant correlation between the numbers of W. recta at baseline and the likelihood of breakdown during the observation period. The number of spirochetes at baseline, however, was significantly related to the changes of probing depth (p greater than 0.001). It was concluded that spirochetes were more closely related to changes of probing depth in this population than the number of W. recta organisms present.

Adult↗
PubMed1986

Depth-force-patterns in periodontal probing.

This investigation was undertaken to study penetration-depth and simultaneous force development during the insertion of a standard periodontal probe tip into a pocket to gain information about the tissue resistance to probing and its relation to the accuracy of depth determination. A piezoelectric force transducer and a linear position transducer were incorporated into a periodontal probe. Depth-force diagrams were obtained on an x-y plotter. In 5 patients requiring treatment for chronic periodontitis, 50 sites were selected and measured 3 times before and 3 times after a treatment phase consisting of hygiene instruction, systematic deep scaling and root planing. The minimal required probing force for reproducible values within a limit of 0.5 mm up to a force of 1.2 N was determined for each record ("b-value") and correlated in a multiple linear regression analysis with a number of clinical parameters of the sites. Depth-force diagrams recorded with the probe showed the characteristics of saturation curves flattening off in the range of 1 N and more. When the probing force was increased from 0.41 N up to 1.2 N, 50% of all measurements showed an increase in depth of more than 0.5 mm. However, increasing from 0.9 to 1.2 N resulted in a change of more than 0.5 mm in only 5% of the measurements. Differences in b-values before and after the treatment were significant (p less than 0.01). Differences related to tooth type (M, PM, I) and conventional pocket depth before treatment were also significant (p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1982

Cerebrospinal fluid and peripheral blood lymphocyte subpopulations in multiple sclerosis. Evaluation by means of monoclonal antibodies (a preliminary note).

We are investigating peripheral blood and cerebrospinal fluid lymphocyte subpopulations in multiple sclerosis patients by monoclonal antibodies directed at T-helper, T-suppressor and total mature T-cell subsets. Patients affected by other neurological diseases are also being studied as a control population. Antibodies' selectivity together with careful cell handling, allowed us a detailed study even of small lymphocyte numbers usually recovered from multiple sclerosis cerebrospinal fluid. First results point to a marked increase in T-helper population, with a helper/suppressor imbalance in MS patients' cerebrospinal fluid, but not in peripheral blood. No difference could be detected between cerebrospinal fluid and peripheral blood lymphocyte subpopulations in control patients. Further work is now needed to achieve more complete and significative results.

Adult↗