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Biomedical subjects

A Mol

Publications and source records attributed to A Mol.

24 records · Page 2Linked to original sources

Application of digital image analysis in dental radiography for the description of periapical bone lesions: a preliminary study.

This paper describes an application of digital image analysis for the description of periapical bone lesion in dental radiography. These techniques enable the problem of observer variability to be circumvented, and can eventually be used for the quantitative assessment of bone lesions. Since periapical bone lesions appear radiographically as dark areas compared with their surrounding tissues, an edge-detection method was developed to extract the boundaries between anatomy and pathology. The original data were transformed in such a way that only the outlines remained. The lesion was assumed to be demarcated by a continuous outline, so all the contour points not being part of a continuous outline were excluded. With only limited operator interaction, the lesion contour could be projected successfully onto the original image. The result of this operation was a simplified diagnostic examination process promising a higher degree of objectivity in periapical bone lesion detection. It is concluded that the results encourage further development of image processing techniques suitable for the definitive detection and diagnosis of periapical bone lesions.

Alveolar Bone Loss↗

Digital image analysis for the diagnosis of periapical bone lesions: a preliminary study.

Digital image analysis techniques enable the problem of examiner variability to be circumvented, and can be used to develop quantitative descriptions of bone lesions. This study investigated a method for describing periapical bone lesions. An edge-detection technique was developed for application to routine periapical radiographs. Most periapical bone lesions appear radiographically as dark areas compared with the surrounding tissues. The digital imaging process resulted in an outline resembling the contour of the image of the lesion present. This contour could be successfully projected on to the original image with only limited operator assistance. Processing of the image resulted in increased definition of the structures present, with considerable noise reduction. The result was a simplified diagnostic examination process that promised a high degree of objectivity in periapical bone lesion detection. It is concluded that the results encourage further development of image processing techniques suitable for the definitive detection and diagnosis of periapical bone lesions.

Image Processing, Computer-Assisted↗

[Quality of dental radiographs. A sample from 52 general practices].

To assess the quality of dental radiographs in general practice, 1000 radiographs in 52 practices were collected and evaluated. The radiographs were judged by two examiners using standard series of X-ray film, showing different degrees of the nine different types of errors studied. Furthermore, the diagnostic quality was assessed; if the diagnostic value was poor, the cause was registered. Only 3.1% of the investigated radiographs met all the criteria, and the quality of 13.4% was found to be poor. The main causes were filmpositioning, density and errors in the category 'residual'. It also appeared that a combination of errors in one radiograph, which were individually not very serious, resulted in an unacceptable radiograph.

Humans↗

Absence of significant autosomal lesions in Huntington's disease.

Peripheral blood from six patients with Huntington's disease (HD) and six controls were cultured in three types of media known to produce fragile sites. A total of 3000 metaphases per group were scrutinized in a blind coded study. No significantly specific 'hot-spot' was found capable of differentiating between HD patients and controls.

Adolescent↗