Acid phosphatase activity examinations and nitrotetrazolium blue reduction test after latex stimulation in peripheral blood neutrophils were performed in the group of 32 coking plant workers. Reference group consisted of 150 men not exposed to any toxic substances. Neutrophils of coking plant workers, comparing with the reference group, revealed decreased activity of acid phosphatase and impaired reduction of nitrotetrazolium blue after latex stimulation. The results suggest the possibility of toxic influence of coking plant environment on the lysosomal enzymes and oxygen-dependent metabolism of neutrophils what subsequently may diminish bactericidal powers.

Acid Phosphatase↗

PubMedDate not supplied

[Activity of glucose-6-phosphate dehydrogenase in erythrocytes of workers at the smelting works plant for manufacture of iron and manganese alloys].

Decreased glucose-6-phosphate dehydrogenase activity has been shown in the red cells of workers employed in the works producing ferro-manganese alloys in comparison with that in the control group. Tobacco smoking and duration of the occupation did not affect the activity of glucose-6-phosphate dehydrogenase in red cells.

Adult↗

PubMedDate not supplied

[Etiological factors in secondary bacterial infections from the authors' own clinical material].

An analysis of etiological factors of secondary bacterial infections was carried out in 64 patients with pneumonias. In most of the patients gram negative rods were cultured. Most often the pneumonias were caused by Klebsiella pneumoniae and Escherichia coli. A single causative agent was found in the majority of the patients (60.7%), less frequently two, least three.

Adult↗

PubMedDate not supplied

[Clinical picture of secondary pneumonia in our observations].

Hundred sixty four patients with the secondary pneumonia were analysed. The secondary pneumonia amounted to 65.8% of all cases of pneumonia treated within several years. Patients' sex, age, clinical symptoms, X-ray findings, coexisting diseases, sequence of the symptoms and the rate of their disappearance were analysed. It was found that the secondary pneumonia is prevailing in males over 40 years of age and most frequently accompany cardiac failure and chronic unspecific respiratory diseases. It is characterized by slow onset and the lack of typical symptoms in the high percentage of patients. Radiological and clinical symptoms disappear more slowly. However, various ausculatory symptoms of pulmonary involvement often accompany the secondary pneumonia and are not directly related to the inflammatory lesion to the lungs.

Adult↗

PubMedDate not supplied

[Cytochemical analysis of selected enzymes in granulocytes from the peripheral blood of coke plant employees].

Cytochemical reactions detecting catalase and myeloperoxidase in the peripheral blood neutrophils were carried out in coke plants employees. Intensity of the cytochemical reactions were expressed as total score and compared with the values obtained in corresponding control group. An increase in both enzymes activity, especially catalase, was seen. It is assumed that the in enzymatic activity may be related to iron-porphyrins being prosthetic group of these enzymes.

Adult↗

PubMedDate not supplied

[Various non-specific immunity proteins in the blood serum of workers in the coke-processing industry].

The concentrations of certain proteins related to non-specific immunity were determined in the serum of cokery workers and in a matched control group. No changes were found in the concentrations of the main proteins of the properdin system, that is properdin and third fraction of complement. However, the level of transferrin was higher in cokery workers. It seems that the harmful effects of the working environment were not changing the function of the properdin system. Raised transferrin level seems to be only a biochemical trace of exposure without essential importance.

Adult↗

PubMedDate not supplied