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Biomedical subjects

A Miotti

Publications and source records attributed to A Miotti.

At least 19 recordsLinked to original sources
PubMed1996

[A statistical epidemiological study of cranio-maxillofacial trauma in the Friuli Venezia Giulia region].

Data corresponding to 17,247 subjects, admitted in Hospital of Friuli Venezia Giulia region, were analyzed in the period between 1984/2/28 and 1993/2/27. All data were selected for for diagnosis, sex, aetiology, age, diagnosis's priority, days of stay in Hospital and locality where the patients live. The results showed 69.31% of the patients were male (range 0-80 years) of 15-19 years (2,605 cases corresponding to 15.1%) and 20-24 years (2,448 patients, 14.2%). More frequently the traumatic pathology was related to injuries of the facial bones (72.22%) and of these 62.13% were fractures of the nasal bones. The major incidence of injuries was caused from unspecified nature's incidents (47.5%), followed by road accidents (31.2%), violence, work accidents and others. The evaluation of single years showed a decrease of traumas from 2,019 cases (1984-85) to 1,759 cases (1992-93), probably caused by traffic regulations. Variables and incidence of cranial-maxillofacial traumas were also examined.

Adolescent↗
PubMed1994

An enhanced surveillance program for adult T-cell leukemia in central Brooklyn.

The Brooklyn Adult T-cell Leukemia/Lymphoma (ATL) study was developed to estimate the incidence of the human T-cell lymphotropic virus type I (HTLV-I)-associated ATL in the Crown Heights/Bedford Stuyvesant community. This central Brooklyn black community is an area which has already been shown in earlier reports to be endemic for HTLV-I-associated ATL. Surveillance has been conducted at seven area hospitals that serve this community, with surveillance already completed at five hospitals. Potential study subjects who are 20 years or older are identified by the review of admission records, discharge summaries, pathology and clinical chemistry reports, or physician referrals. Diagnoses of leukemia or lymphoma, or the presence of leukocytosis or hypercalcemia are used as criteria to identify the subjects. Participating subjects give a sample of blood for the determination of HTLV-I infection by serologic tests. At the time of enrollment, subjects provide demographic information including age, sex and birthplace. After one year of surveillance at five hospitals (39.5% of inpatient beds in the catchment), we have identified 12 cases of HTLV-I-associated ATL. The mean age of the ATL patients was 50 years, with patients being predominantly female (83.3%) and often Caribbean immigrants (83.3%). Interestingly, 42% of our cases were identified solely by findings of hypercalcemia from clinical chemistry reports. The remaining ATL cases were identified by physician referral. This enhanced surveillance program that uses both clinical and laboratory criteria for ATL case ascertainment can serve as a prototype for similar surveillance in other areas endemic for HTLV-I-associated ATL--an important effort because of the strong potential for disease prevention.

Adult↗
PubMed1991

Ultrastructural findings on the interface between hydroxylapatite and oral tissues.

Two patients were treated with surgical implantation of synthetic, granular, nonporous hydroxylapatite to correct bone defects around dental implants. Ultrastructural examination of biopsy specimens taken several months later showed that the hydroxylapatite material was encapsulated mostly by fibrous connective tissue, without any signs of active inflammation. Osteoid and mature bone were also present in many areas. Under the electron microscope, an electron-dense delimiting band was detected at the interface of the tissue and the material. A polygonal, networklike structure, originating from the electron-dense layer and penetrating into the periphery of the hydroxylapatite granules, was also observed. These findings confirm the results of previous studies, in which it was hypothesized that the electron-dense structures were of a mucopolysaccharide nature and might prove the close bond between the hydroxylapatite and the tissues.

Alveolar Process↗
PubMed1986

Another Italian family with mandibuloacral dysplasia: why does it seem more frequent in Italy?

We describe three patients (one female and two males in a sibship of 11) with mandibuloacral dysplasia. Only eight families have been reported previously, and of these, four were of Italian origin. The phenotypic spectrum of the condition is delineated and its variability is stressed. The observation of three affected members of both sexes with normal parents supports the hypothesis of autosomal recessive inheritance. The reasons for the high frequency of the condition in Italy are discussed; a local selective advantage for heterozygotes and founder effect might be involved.

Abnormalities, Multiple↗
PubMed1986

Dental extraction in congenital hemorrhagic patients.

125 dental extractions were performed in patients with hemophilia A, B, von Willebrand disease and rare coagulopathies. The missing factor was brought to a level of 15-40% according to the degree of surgical trauma. In the majority of cases a single pre-extraction administration of concentrate was sufficient. Antifibrinolytics were administered to the patients (tranexamic acid, 60 mg/kg/day) for 8-10 days. After tooth extraction, a fibrin sponge was positioned using anti-traumatic cross suture. In 90% of cases there was no bleeding, in the others modest easily controllable hemorrhagic episodes. Our results show that it is sufficient in hemophilia A and B to use low doses of antihemophilic concentrate (10-20 U/kg) and frequently a single pre-extraction administration. In rare coagulopathies the hemostatic procedure and dental management have also to be similar to those used in hemophilia A and B.

Adult↗