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Biomedical subjects

A Miniti

Publications and source records attributed to A Miniti.

At least 37 records · Page 2Linked to original sources
PubMed1991

["Osteogenesis imperfecta": some differential particularities with otospongiosis].

The authors present 3 cases of osteogenesis imperfecta, with auditory repercussions similar to otospongiosis. A review of the literature of the pathology highlights its relationship with the temporal bone. The findings and treatment of 3 cases are discussed. The author conclude that this pathology may suggest otospongiosis with a progressive neuro-sensorial loss of hearing. The treatment of choice is the use of a hearing aid, rather than surgery.

Adult↗
PubMed1991

[Infantile fibromatosis: report on two cases].

Fibromatosis is an aggressive, infiltrating, non-metastasizing disease characterized by a benign neoplastic histology. These lesions tend to infiltrate the soft tissues and adjacent bony tissues, hence the term "aggressive infantile fibromatosis". Two cases of this rare pathology are presented and discussed.

Facial Neoplasms↗
PubMed1991

Use of the Silvermann-Franklin biopsy needle for the diagnosis of intra-sinusal lesions, especially of the maxillary sinus.

This report proposes the use of a new technique in the diagnosis of pathology of the maxillary sinus, including neoplasm, using the Silvermann-Franklin" needle. The procedure consists of approaching the diseased sinus through the canine, as in conventional biopsies, with the removal of fragments using forceps. Ten patients with an X-ray suggesting a mass in the maxillary sinus were studied. An 80% correlation was found between the anatomical and pathological findings of the biopsy and the subsequent surgical findings. The advantages of this method include the low risk, performance under local anaesthetic in an out-patient mode, the possibility of obtaining the diagnosis prior to surgery, and the possibility of obtaining deep-seated tissue fragments.

Adolescent↗
PubMed1990

Autoimmune sensorineural hearing loss: a preliminary experimental study.

The aim of this study was to compare cochlear alterations produced by induction of anti-type II collagen antibodies with alterations produced by passive transfer of anticochlear antibodies. Guinea pigs (GP) were used. The anticochlear antibodies were obtained by injecting GP membranous cochlea plus Freund's adjuvant into rabbits. After partial purification of the immunoglobulins, the antibodies (20 mg) were injected intramuscularly into 10 normal GP. A second group of 10 normal GP received intramuscular injections of purified chicken type II collagen (1 mg) plus Freund's adjuvant. A control group of 10 normal GP was studied under the same conditions without any stimulus. The cochlea function was analysed with brainstem evoked audiometry (BERA). The structural study was carried out by immunofluorescent and hematoxylin preparations. The results showed structural alterations in both experimental groups (loss of nucleus in the spiral ganglion); however, significant changes in the BERA were not found. Only increase of the latency of wave I could be seen. These preliminary results support the hypothesis that antibodies to collagen type II may play an important role in human autoimmune sensorineural hearing loss, but the possible existence of other cochlear antigens is discussed.

Animals↗
PubMed1990

Clinical and surgical aspects of cholesteatomas in children.

A review of 101 charts of pediatric patients who underwent surgery for cholesteatoma in the Hospital das Clínicas, São Paulo, Brazil, showed that the peak incidence was in the 10- to 15-year-old age group (mean age, 10.7 years). A high incidence of complications (45.5%) and a significant functional impairment (air-bone gap greater than 40 dB in 49% of patients) were some of the particular features of our patients. Radical or modified radical mastoidectomies were performed in 75 cases (74.3% of cases). The open technique was chosen primarily to eradicate cholesteomatous disease, but the satisfactory functional results also achieved support our preference for this technique.

Adolescent↗
PubMed1989

Comparison between fibrin tissue adhesive, epineural suture and natural union in intratemporal facial nerve of cats.

Our objective was to study intratemporal anastomosis of the facial nerve in cats. Clinical, electrophysiological and histological results of the use of fibrin tissue adhesive, epineural suture and natural adhesion were compared. The 30 adult cats studied had undergone mastoidectomy exposure, and section of the facial nerve 1 cm before its exit from the stylomastoid foramen. Anastomosis was then undertaken, using epineural suture combined with stabilization through fibrinic tissue adhesive, and union of the stumps without stabilizing them. Each type of anastomosis was carried out in 10 animals. Clinical, electrophysiological and histological assessments of both the site of anastomosis and the ventral branch of the facial nerve followed the aforementioned procedures. By means of statistical analysis, the authors reached the following conclusions: 1) Considering the clinical assessment per se, both groups with fibrinic tissue adhesive and suture showed similar features and results, which in both cases were better than those following natural union. 2) Considering the electrophysiological results per se, the use of fibrin tissue adhesive was superior to any other method used. 3) Considering the histological examination per se, both groups with fibrin tissue adhesive and suture revealed similar features which were more favourable than those shown by natural union. 4) In the overall comparison of the various parameters in the three groups, the use of fibrin tissue adhesive achieved better results than any other method. Based on the results of this study, the authors conclude that the use of fibrin tissue adhesive has technical advantages, and that the results of this use outweigh those achieved with both epineural suture and natural union. The authors recommend this technique as the most beneficial to be resorted to, for intrapetrous anastomosis of the facial nerve.

Anastomosis, Surgical↗
PubMed1985

X-linked mixed hearing loss: four case studies.

To present four cases of an X-linked inner ear malformation, the authors studied inner ear malformations and present here all the radiological, genetic, and audiological tests of these patients. The importance of this paper is to reinforce the differential diagnosis between this pathology and otosclerosis in order to avoid surgical procedures.

Acoustic Impedance Tests↗
PubMed1985

[Topodiagnosis in peripheral facial paralysis].

The topodiagnosis allows the physician to determine the topographic localization of pathology involving the facial nerve. It is based on clinical tests that evaluate the function of each one of the rami of the facial nerve. With a statistic of 873 patients, the Facial Nerve Group of Hospital das Clínicas, São Paulo University, found that suprageniculate lesions are responsible for 50% of the facial nerve involvement of several etiologies. Based on these results, the physician is able to develop a rationale for therapy and surgical access for facial nerve lesions.

Facial Paralysis↗
PubMedDate not supplied

A pathway for information transmission to the inner ear. Application to cochlear implants.

The use of cochlear implants as an aid to neurosensory deafness is becoming an established procedure. The transmission of a processed speech signal is accomplished either transcutaneously via radiofrequency or percutaneously by connector coupling. Whereas the former is sensitive to electromagnetic interference, the latter increases the risk of infection. To overcome these disadvantages, an infrared (IR) system for transmission through the tympanic membrane was devised and tested. The transmitter/receiver consisted of an IR light emitting diode (LED; 920 nm) and a photovoltaic cell. The LED was placed inside the auditory canal of four dogs and the photovoltaic cell in the tympanic cavity over the cochlear promontory. A sinusoidal signal modulation was applied to the LED. The emitted signal was detected undistorted after crossing the tympanic membrane, with an average absorbance of 20%. High frequency cut-off was adequate for cochlear implant purposes and audio prosthetic devices in general. The authors conclude that the tympanic membrane may be used as a translucent sealed interface to transmit data in the audio range to the middle and inner ears, with small power loss, good frequency response, and immunity to interference.

Acoustic Stimulation↗