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Biomedical subjects

A Milazzo

Publications and source records attributed to A Milazzo.

44 records · Page 3Linked to original sources
PubMedDate not supplied

[HIV infection in an autonomous Spanish community (La Rioja). Features, trends and conclusions applicable to other regions].

BACKGROUND: The epidemiologic characteristics of HIV infection in La Rioja (Spain) were studied and the future tendencies of the same analyzed. METHODS: The data from official Health sources were collected and analyzed. RESULTS: In La Rioja, the 5th region in Spain regarding to AIDS incidence, the duplication time of the number of cases continues to shorten. The number in December 1991 was 81. The heterosexual route of infection was 5% of the cases of AIDS up to December 1990 and in 1991 it was 15%, while, with regards to the total number of seropositive subjects, the number rose from 0.3% in December 1990 to 10% in 1991. One thousand one hundred fifty-one seropositive patients were detected in December 1991 representing seroprevalence of 0.34% which reaches 1.14% in the age range between 18-32 years. Mean hospital stay was 23.6 days with 3,032 hospital stays calculated for 1991 representing 8.3 occupied beds/day. There are presently 92 patients undergoing antiviral treatment. Between 43-69 new cases of AIDS have been calculated for 1992. CONCLUSIONS: 1) Medical care should be provided to a greater number of seropositive people to avoid early deterioration. 2) The increase in heterosexual infection is alarming. 3) The need for rehabilitation centers for drug abusers and social alternatives to prostitution is clear. 4) Organized campaigns pointing out and returning the dignity and value of life and therewith the role of human sexuality are needed. 5) Alternative means to conventional hospitalization is required.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Lymphocyte subpopulations, neopterin, and beta-2-microglobulin: relationship with clinical stage, risk of progression to AIDS and presence of active infection in HIV infection].

BACKGROUND: The aim of the present study was to evaluate the relation between the number of CD4 lymphocytes, the CD4/CD8 ratio and the plasma levels of neopterin and beta-2 microglobulin, and the clinical status, risk of progression without of active opportunistic infections, among HIV-infected patients. METHODS: Seventy-two patients infected by HIV in different clinical groups were evaluated upon entering the study and following a mean follow up of 6 months for the parameters studied. RESULTS: The values of CD4 lymphocytes and neopterin were related with the clinical status according to the CDC's classification, with no significant differences existing in the beta-2 microglobulin level. The CD4 count as well as the neopterin and the beta-2 microglobulin levels differed significantly when classified to the patients with regard to the risk of progression to AIDS throughout the study. The presence of active opportunistic infections was related with significantly higher concentrations of neopterin without differences recorded for the remaining parameters. CONCLUSIONS: The parameters studied are good markers or both clinical status and/or the risk of short-term progression to AIDS. Neopterin levels are high during acute infections. Therefore, its prognostic value should be cautiously evaluated in this situation.

Acquired Immunodeficiency Syndrome↗