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Biomedical subjects

A Meister

Publications and source records attributed to A Meister.

At least 361 records · Page 20Linked to original sources

Asparagine synthetase activity of mouse leukemias.

Various transplanted leukemias and normal tissues of the mouse were tested for asparagine synthetase activity. Leukemias susceptible to suppression by asparaginase have little or no synthetase activity. In contrast, leukemias insensitive to asparaginase exhibit substantial and often very high asparagine synthetase activity. Asparaginase-resistant variants of sensitive leukemias also have considerable synthetase activity. Thus the requirement by certain malignant cells of exogenous asparagine, which entails sensitivity to asparaginase, may be ascribed to lack of asparagine synthetase. Development of asparaginase-resistant variants from asparaginase-sensitive lines is consistently associated with acquisition of asparagine synthetase activity.

Animals↗

New symbols for the amino acid residues of peptides and proteins.

A system of symbols for the amino acid residues of proteins and peptides is proposed. The symbols convey immediate meaning in chemical terms and therefore allow rapid recognition of the distribution and frequency of occurrence of the various functional groups. The system is readily adaptable to description of new amino acids and amino acid modifications.

Amino Acid Sequence↗