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Biomedical subjects

A Meijer

Publications and source records attributed to A Meijer.

83 records · Page 5Linked to original sources

High risk factors for childhood asthma.

Comparing school age asthmatic and non-asthmatic children from strongly allergic families, who contracted atopic dermatitis in early infancy, the following findings in the asthmatic boys emerged: a lower standard of education of their mothers, persistence of the infantile eczema beyond the age of two and several psychological factors relating to the child, the mother and maternal grandparents.

Asthma↗

Psychological factors in maternal grandparents of asthmatic children.

The presently perceived past family interactions between mothers and maternal grandparents of asthmatic children and nonasthmatic children were compared. All the children included in this study had a common factor in that they suffered from early infantile eczema in the 1st year of life, and in their families there were many cases of asthma, hay fever, and eczema. With the use of two different test instruments for the measurement of family relationships, it was found that maternal grandmothers of asthmatic boys had a highly positive relationship with the mothers of the boys and that the maternal grandfathers were perceived by the mothers as rejecting figures. Even though the correlation between the two tests was rather high, they showed differences in their sensitivity. There was a striking difference between the mothers of asthmatic boys and the mothers of asthmatic girls in both tests. This fact together with the established greater vulnerability of boys to asthma seem to justify studying the sexes separately. It could be assumed that the asthmatic and nonasthmatic children in this study had a similar constitutional-familial allergic predisposition and that the differences between these groups of children were mainly influenced by environmental factors. The mothers' perception of the family relationship with their parents was considered to be minimally influenced by the asthma of their children.

Asthma↗

Asthma predictors in infantile atopic dermatitis.

In a search for predictive factors in early childhood for later developing childhood asthma, sixty chidren who suffered in the first year of life from atopic dermatitis were examined at ages between 6-11 years. There were 40 boys and 20 girls, of whom 21 were asthmatic boys and 10 asthmatic girls. The non-asthma group was similar to the asthma group in age, sex and socio-economic background and familial-hereditary background. The psychosocial aspects of the study were not reported in this paper. The atopic dermatitis followed a different pattern in the asthmatic group than in the non-asthma group. A continuation of the atopic eczematous condition in infancy beyond two years appeared to be highly predictive for future childhood asthma. Severity of the eczema in infancy does not seem to be a strong predictor in boys and not at all in the small group of girls. Persistent eczema appeared twice as much in the asthmatic boys as in the asthmatic girls. There was no distinct difference between the asthmatic children and the non-asthmatic children in time of onset of the infantile eczema nor in the location of the atopic dermatitis.

Age Factors↗

The first international intercomparison of EPR-dosimetry with teeth: first results.

Intercomparison of EPR-dosimetric techniques using tooth enamel had been performed in order to check whether the results produced by different laboratories are consistent and accurate. Participants were supposed to evaluate doses applied to pulverized enamel samples, using routine techniques from their laboratories. The intercomparison has demonstrated a great variety of methods used for dose reconstruction. Peculiarities of experimental approaches are discussed systematically in terms of procedure for recording the EPR-spectra, determination of the amplitude of the radiation induced signal, determination of the dose, and error propagation.

Dental Enamel↗

Psychiatric problems of hemophilic boys and their families.

Some often described clinical observations on psychological problems of hemophilic boys and their families, were examined in a controlled study of twenty mothers of hemophilic boys and the same number of mothers of non-hemophilic healthy boys of the same age and similar socio-demographic background. The findings confirmed statistically the existence of considerable defiance and hostility of the boys and depressed mood of the mothers. The fathers showed a trend to provide little control and support. The defiance of hemophilic boys contrasts with the frequently described tendency towards compliance of asthmatic children. The differences between these two conditions are discussed. Therapeutic implications of the findings are outlined.

Adult↗

Idiopathic ventricular tachycardia--characterisation and radiofrequency ablation.

Forty patients (14 women and 26 men; mean age 40 +/- 13 years, range 7 to 60) diagnosed to have idiopathic ventricular tachycardia (right ventricular 28, left ventricular 12) underwent electrophysiologic study and radiofrequency catheter ablation. Echocardiography, signal averaging, magnetic resonance imaging and cardiac catheterisation with angiography were used as indicated to rule out identifiable underlying etiologies. Gross localisation of the area of origin of the ventricular tachycardia from the surface electrocardiogram could be made in all cases. Accurate localisation of the site of origin was done by activation mapping and pace mapping. Radiofrequency application was successful in achieving a cure in 34 (85%) patients, with a mean of 8.3 +/- 4.7 energy applications and a fluoroscopy time of 38 +/- 19 minutes. Unsuccessful cases were characterised by wide and slurred QRS complexes during ventricular tachycardia, possibly indicating a deeper intramyocardial or epicardial site of origin of the tachycardia. Radiofrequency ablation appears to be the treatment of choice for symptomatic idiopathic ventricular tachycardia, having a high success and safety rate.

Adult↗