Search PubMed⌕ Search

Biomedical subjects

A Mehta

Publications and source records attributed to A Mehta.

320 records · Page 18Linked to original sources
PubMedDate not supplied

Should androgen levels be measured in hirsute women with normal menstrual cycles?

In a study of 129 consecutively referred hirsute women, 40% had regular menstrual cycles. About one half of such individuals had elevated levels of one or more androgens (DHEAS, testosterone or free testosterone index), whereas a higher proportion (69%) of hirsute women with oligo-amenorrhea were abnormal. Mean androgen levels in regularly cycling hirsute women were higher than in controls, but lower than or equal to those in oligo-amenorrheic hirsutism. Thus, menstrual status does not predict androgen status in hirsute women.

Adult↗
PubMedDate not supplied

Tracheobronchopathia osteochondroplastica.

Tracheobronchopathia osteochondroplastica (TO) is a rare and benign disorder characterized by cartilagenous and/or osseous submucosal deposits projecting into the laryngotracheobronchial lumen. The disorder is usually asymptomatic and most of the cases have been diagnosed incidentally at autopsy or during bronchoscopy. A case of TO in association with bronchogenic carcinoma is being reported for its rarity.

Bronchial Diseases↗
PubMedDate not supplied

Controversies in the management of acute pancreatits.

INTRODUCTION: Acute pancreatitis accounts for three to five percent of admission to hospital for abdomen pain. Though most are of mild form, the severer form takes a toll of some ten percent. AIMS AND OBJECTIVES: This study aims to make a retrospective analysis of some fifty four admissions for acute pancreatitis admitted to Kathmandu Medical College Teaching Hospital in the past twenty four months. It also aims to highlight some of the controversies that have come up as to its management. RESULTS: Among the 54 admissions for acute pancreatitis, there were thirty nine patients. Sixteen (41%) of them were female and twenty three (51%) male. Their ages ranged from twenty one to ninety years, with an average of forty one years. Surprisingly no patients were between sixty to eighty years bracket. Thirteen (33%) of the patients had gall stones in ultrasound. Two (5%) of the patients were suffering from mumps and Eleven (28%) no causal factors were found. While thirteen (33%) patients suffered from alcoholic pancreatitis. All of them were male. Of the alcoholic group, five (38%) had recurrent attacks. Five (38%) from the biliary and two (18%) from the idiopathic group had recurrent attacks. Four patients were operated on emergency basis. Three with the diagnosis of peritonitis and another eighty four year old lady with features of associated cholangitis were found to have acute pancreatitis at operation. One of them underwent peritoneal toileting; two had cholecystectomy and peritoneal toileting while the eighty four year old lady underwent cholecystectomy, common bile duct exploration and peritoneal toileting. All fared well post-operatively.

Acute Disease↗
PubMedDate not supplied

Effect of antibiotics in controlling the production of cell wall degrading enzymes in vitro and disease development in vivo.

Production of cellulolytic, proteolytic and pectolytic enzymes by all the three isolates of A. niger was inhibited by all the tested antibiotics. Nystatin (500 ppm) could cause complete inhibition of PG enzyme production, whereas PMG production was checked by amoxicillin, nystatin, chloramphenicol and raficillin at 100 ppm concentration. All the antibiotics at 500 ppm concentration checked the cellulase production in all the three isolates of A. niger. Nystatin and raficillin (100 ppm) completely controlled the protease production in all the three isolates of A. niger. A positive correlation was observed with enzyme production and mycelial biomass in three isolates of A. niger, All the antibiotics at both the concentrations (100 and 500 ppm) could also check the rottening in all the three fruits in vivo conditions.

Anti-Bacterial Agents↗
PubMedDate not supplied

Medical termination of pregnancy and concurrent contraceptive adoption in rural India.

This study reports on 2,755 women seeking medical termination of pregnancy (MTP), and concurrent contraceptive acceptance, at a clinic in rural India from 1976 to 1987. The level of contraceptive acceptance among married women seeking MTP between 1976 and 1987 was 88.2 percent. Among married women seeking MTP in their first trimester of pregnancy, 43.4 percent accepted the IUD as a method of contraception and 41.8 percent accepted sterilization. By contrast, only 11.5 percent of women in their second trimester accepted the IUD, but 70.2 percent accepted sterilization. Seventy-two percent of the unmarried women and 43 percent of the married women seeking MTP were in their second trimester. Recommendations are made to: (1) combine contraceptive services and counseling with MTP whenever possible, (2) examine the consequences of policies that exclude unmarried women from contraceptive services, (3) investigate the reasons why so many women in this study sought MTP so late in pregnancy, and (4) obtain information on the determinants of contraceptive acceptance among women who seek MTP.

Abortion, Induced↗
PubMedDate not supplied

Role of radiation therapy in carcinoma of the gall bladder--a preliminary indian experience.

Carcinoma of the gall bladder has a poor prognosis despite surgical resection of the tumour. We prospectively enrolled 21 patients with histologically proven adenocarcinoma of the gall bladder, who were stage III or beyond for post operative radiotherapy. Six month survival was 67% (14 of 21 patients) while one year survival was 33% (7 out of 21 patients) and five year survival was 23% (5 of 21 patients). Those patients who had residual disease or were considered inoperable at surgery had no improvement in survival. The 1 year and 5 year survival in these patients was encouraging with radiotherapy in the present open labelled study of radiotherapy in patients with carcinoma of the gall bladder.

Adenocarcinoma↗
PubMedDate not supplied

Effects of drill speed on heat production and the rate and quality of bone formation in dental implant osteotomies. Part I: Relationship between drill speed and heat production.

The amount of heat produced by dental implant osteotomy (receptor site) preparation at different speeds and the effects of heat production on the prognosis of implant treatment are controversial. In Part I of this two-part study, heat production was measured in vivo during osteotomy preparation at low (maximum 2,000 rpm), intermediate (maximum 30,000 rpm), and high (maximum 400,000 rpm) speeds in the rabbit tibia, and an inverse relationship was observed between drill speed and heat production. For the measurement of heat production (Part I), a thermocouple probe was inserted into a prepared receptor site in the anteromedial aspect of the tibial metaphysis. Temperature was recorded while an osteotomy was drilled 1 mm from the thermocouple receptor site. Distilled water was used as coolant in conjunction with all drilling, and all osteotomies were prepared by a single researcher to eliminate the variable of interoperator difference in technique. An inverse relationship was observed between drill speed and heat production. An analysis of variance indicated significant differences in heat production among the three drilling speeds (P < 0.05). The results of Part 1 of this study indicate that for the configuration and material of bur used, the high-speed range minimizes heat production.

Analysis of Variance↗
PubMedDate not supplied

Effects of drill speed on heat production and the rate and quality of bone formation in dental implant osteotomies. Part II: Relationship between drill speed and healing.

In Part I of this two-part study, the authors investigated heat production during osteotomy drilling at three different speeds, and determined that high-speed drilling produced the least heat when using 700 XL carbide burs. Part II of the study histologically examines the rate and quality of healing after drilling osteotomies at the three speeds in the mandible. Osteotomies were histologically examined 2, 4, and 6 weeks postoperatively. Histologic findings suggested that in the initial 6 weeks, the rate of healing and quality of new bone formation were higher after high-speed drilling than after low- or intermediate-speed drilling. These results, when considered with the results reported in Part I in which a 4.3 degrees C difference in heat production was observed between the speeds, seem to imply a relationship between heat production and healing for osteotomy drilling.

Animals↗
PubMedDate not supplied

A pilot programme of MRSA surveillance in India. (MRSA Surveillance Study Group).

This surveillance study was conducted simultaneously at three centres across India. A total of 13,610 test samples from various sites were obtained. Microbiological methods employed were similar at the three centres. Identification of S aureus was based on the recognition of the production of coagulase with positive isolates being recorded as S aureus. Both tube coagulase tests and slide coagulase test were performed. Antimicrobial susceptibility testing of the isolated strains of staphylococcus aureus and staphylococcus epidermidis to various antimicrobial discs were carried out according to standardized disk diffusion method recommended by NCCLS. Of the total 739 cultures of S aureus, 235 (32%) were found to be multiply resistant with the individual figures for resistance being 27% (Bombay), 42.5% (Delhi) and 47% (Bangalore). MRSA is emerging to be a significant problem pathogen in the surgical setting with vancomycin probably the only reliable choice for these infections.

Cross Infection↗
PubMedDate not supplied

Right ventricular endocarditis due to infection of pacemaker apparatus.

This article describes an unusual case of endocarditis in a 73-year-old man with a permanent pacemaker. Echocardiography revealed vegetations in the right ventricle below the tricuspid valve only, and he required open heart surgery for removal of the pacemaker system. This case demonstrates the potentially protracted course of infective endocarditis many years after pacemaker insertion. It also emphasizes the importance of echocardiography in diagnosing right ventricular vegetations; and the need for total replacement of the endocardial pacing system whenever it becomes infected.

Aged↗