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Biomedical subjects

A McMahon

Publications and source records attributed to A McMahon.

At least 109 records · Page 6Linked to original sources

Prevention and management of pressure sores.

Continuity of care is needed when transferring patients at risk of developing pressure sores. The tools used to assess such patients must be consistent. A turning clock system has been developed for use with the patient.

Aged↗

Chronic lead exposure effects in the cynomolgus monkey (Macaca fascicularis) testis.

Although reproductive consequences of high circulating blood lead levels (> or = 60 micrograms/dL) have been reported, potential adverse effects of chronic lead exposure in males that result in low to moderate blood lead levels (10-25 and 26-60 micrograms/dL, respectively) are unknown. Effects of chronic lead exposure to testis ultrastructure were determined in the cynomolgus monkey after oral administration of lead acetate (1500 micrograms/kg BW/day) in a vehicle in the following groups: from birth to 10 years (lifetime), postnatal day 300 to 10 years (postinfancy), and postnatal day 0-400 (infancy); monkeys in the control group received only the vehicle (95% glycerol and 5% distilled water). At age 10 years, circulating lead concentrations in lifetime and postinfancy-dosed monkeys were approximately 35 micrograms/dL, and in control and infancy animals the concentrations were < 1.0 microgram/dL. Sertoli and spermatogenic cells of dosed monkeys from the infancy and lifetime groups revealed injuries. Chronic exposure to lead that results in moderate blood lead concentrations induced persistent ultrastructural alterations in the cynomolgus monkey testis. Results of this study on the primate, following extrapolation to humans, could influence further refining of the impact of environmental lead contamination concentrations vis-à-vis the health of children, adults, and aged human beings.

Animals↗

Research & development co-ordinating centre.

This year the RCN launched its Research and Development Co-ordinating Centre, the main focus of which is a web site that allows nurses to access extensive R&D-related information on a range of topics. In this report, the authors explain the benefits for nurses and patients and how interacting with the site will shape its future development.

Academies and Institutes↗

Research funding.

The RCN Research and Development Co-ordinating Centre is striving to become the source of information on funding opportunities for nurses.

Clinical Nursing Research↗

The policy context.

Explore the source record for details and available documents.

Clinical Nursing Research↗

Supporting research.

Explore the source record for details and available documents.

Directories as Topic↗

Research ethics.

Explore the source record for details and available documents.

Ethics Committees↗

A force for the future.

Explore the source record for details and available documents.

Education, Nursing, Baccalaureate↗

Supporting R&D: the role of a professional organisation, Part 1.

The first of two articles describes how a professional organisation responded to external developments and tried to co-ordinate its research and development (R&D) activity. For the first time an attempt was made to develop a strategy by eliciting the views of stakeholders. The R&D agenda was examined from the perspective of research, management, education and practice and led to the development of an agreed strategy for the Royal College of Nursing. The suitability of this approach as a mechanism for strategy development and as a lever for change is examined and its potential pertinence to other organisations is discussed.

Attitude of Health Personnel↗

Supporting R&D: the role of a professional organisation, Pt 2.

This second of two articles describes how a professional organisation responded to external developments and tried to co-ordinate its nursing professions' response to research and development activity. For the first time an attempt was made to develop a strategy by eliciting the views of stakeholders. The R&D agenda was examined from the perspective of research, management, education and practice and led to the development of an agreed strategy for the RCN. The suitability of this approach as a mechanism for strategy development and as a lever for change is examined and its potential pertinence to other organisations is discussed.

Diffusion of Innovation↗

An ultrasound study of the effect of chronic lead exposure on endometrial cycle changes in the female cynomolgus monkey.

The effect of up to 10 years of lead (Pb) exposure (1500 micrograms/kg BW/day) on endometrial cycle changes in adult cynomolgus monkeys (n = 30) were examined by real-time ultrasound. Pb exposure had no effect on peak serum estradiol (E2) or progesterone (P4) concentrations, menstrual cycle length, and endometrial response to gonadal steroids as determined by ultrasound.

Animals↗