Search PubMed⌕ Search

Biomedical subjects

A McLaughlin

Publications and source records attributed to A McLaughlin.

43 records · Page 3Linked to original sources

Catheter patrols: a unique way to reduce the use of convenience urinary catheters.

The increased risk of infections among elders has been was documented. Elder patients often have atypical signs and symptoms that lead to delays in diagnosis and treatment of infection. Urinary incontinence is often overlooked as a sign of infection because of the stereotypical belief that urinary incontinence is a normal part of the aging process. This belief can lead to overuse of indwelling urinary catheters and place the elder patient at even greater risk for infection. The Centers for Disease Control and Prevention's "Guidelines for Prevention of Catheter-Associated Urinary Tract Infections" lists four criteria that are helpful in determining appropriate urinary catheter usage. These guidelines, along with ongoing nursing assessment of the patient's urinary catheter need, play an important role in protecting elder patients from unnecessary catheter-associated urinary tract infections.

Aged↗

Cerebral magnetic resonance image segmentation using data fusion.

OBJECTIVE: A semiautomated method is described for segmenting dual echo MR head scans into gray and white matter and CSF. The method is applied to brain scans of 80 healthy children and adolescents. MATERIALS AND METHODS: A probabilistic data fusion equation was used to combine simultaneously acquired T2-weighted and proton density head scans for tissue segmentation. The fusion equation optimizes the probability of a voxel being a particular tissue type, given the corresponding probabilities from both images. The algorithm accounts for the intensity inhomogeneities present in the images by fusion of local regions of the images. RESULTS: The method was validated using a phantom (agarose gel with iron oxide particles) and hand-segmented images. Gray and white matter volumes for subjects aged 20-30 years were close to those previously published. White matter and CSF volume increased and gray matter volume decreased significantly across ages 4-18 years. White matter, gray matter, and CSF volumes were larger for males than for females. Males and females showed similar change of gray and white matter volumes with age. CONCLUSION: This simple, reliable, and valid method can be employed in clinical research for quantification of gray and white matter and CSF volumes in MR head scans. Increase in white matter volume may reflect ongoing axonal growth and myelination, and gray matter reductions may reflect synaptic pruning or cell death in the age span of 4-18 years.

Adolescent↗